Inflammatory and Vascular MarkersVitamin D supplementation

Clinical evidence dossier

Vitamin D supplementation

Malondialdehyde (MDA)

Evidence signal

Authoritative evidence signal

strong

This is an authoritative evidence signal supplied by Clinical Reference. It is not a formal clinical grade, treatment recommendation, or pooled effect estimate.

Evidence snapshot

Authoritative support records
3
Supporting studies available for review
3
Randomized trials
3
Reported effects
7

Clinical conclusion

Vitamin D supplementation shows a moderate positive evidence signal for improving Malondialdehyde (MDA) across the studied comparisons.

The conclusion and evidence-signal classification are distinct authoritative fields and are reproduced as published.

Observed effects

Evidence composition

Non-randomized studies
0
Other designs
0
Unresolved designs
0
Magnitude-eligible effects
0

Consistency

Authoritative consistency classification

mostly_consistent

Positive
2
No effect
1
Mixed
0
Negative
0

Population and applicability

Structured population data were available for 3 of 3 supporting studies. 2 studies described participants with type 2 diabetes. 2 studies described adult participants.

This population information refers to the materialized supporting studies available for review. Omitted support records remain part of the authoritative support accounting and are available through the audit experience.

View reported population descriptions

These descriptions are reported across the supporting studies; they are not a single synthesized population.

  • Adults diagnosed with type 2 diabetes.
  • Patients experiencing oxidative stress related to diabetes.
  • Pregnant women diagnosed with gestational diabetes mellitus.
  • Women in the study were likely in their second or third trimester.
  • Adults diagnosed with Type 2 Diabetes.
  • Individuals seeking to manage inflammation related to diabetes.

Limitations

  • 3 of 3 studies with duration data have follow-up of 12 weeks or less.

Supporting evidence

Inspect the authoritative studies and omitted support records for this dossier.

View supporting evidence