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Cardiovascular Risk

Choose an intervention dossier to evaluate the supplied synthesis and supporting evidence.

This is an authoritative evidence signal supplied by Clinical Reference. It is not a formal clinical grade, treatment recommendation, or pooled effect estimate.

5 dossiers37 included studies7 limited studies

5 of 5 dossiers shown

Clinical Reference

Semaglutide

Semaglutide → Composite cardiovascular events (CV death, MI, stroke, HF hospitalization)

Semaglutide shows a strong positive evidence signal for improving Composite cardiovascular events (CV death, MI, stroke, HF hospitalization) across the studied comparisons.

ConsistencyScore™
mostly_consistent
Supporting studies: 7 supporting studies
Open dossier
Clinical Reference

Semaglutide

Semaglutide → Nonfatal stroke

Semaglutide does not show benefit for Nonfatal stroke in the available evidence and may be associated with worse results.

ConsistencyScore™
mixed
Supporting studies: 4 supporting studies
Open dossier
Clinical Reference

Semaglutide

Semaglutide → Cardiovascular events

Semaglutide shows a strong positive evidence signal for improving Cardiovascular events across the studied comparisons.

ConsistencyScore™
consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Semaglutide

Semaglutide → All-cause mortality

Semaglutide has a small positive evidence signal for All-cause mortality, but the clinical interpretation is limited.

ConsistencyScore™
mixed
Supporting studies: 6 supporting studies
Open dossier
Clinical Reference

Semaglutide

Semaglutide → Cardiovascular death

Semaglutide does not show benefit for Cardiovascular death in the available evidence and may be associated with worse results.

ConsistencyScore™
mostly_consistent
Supporting studies: 3 supporting studies
Open dossier