Browse by outcome

Glycemic Control

Choose an intervention dossier to evaluate the supplied synthesis and supporting evidence.

This is an authoritative evidence signal supplied by Clinical Reference. It is not a formal clinical grade, treatment recommendation, or pooled effect estimate.

23 dossiers112 included studies32 limited studies

23 of 23 dossiers shown

Clinical Reference

Insulin therapy

Insulin therapy → Glucose iAUC (OGTT)

Insulin therapy shows a moderate positive evidence signal for improving Glucose iAUC (OGTT) across the studied comparisons.

ConsistencyScore™
mostly_consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Empagliflozin

Empagliflozin → Fasting Plasma Glucose (FPG)

Empagliflozin shows a moderate positive evidence signal for improving Fasting Plasma Glucose (FPG) across the studied comparisons.

ConsistencyScore™
consistent
Supporting studies: 4 supporting studies
Open dossier
Clinical Reference

Structured multidisciplinary case management

Structured multidisciplinary case management → Fasting Plasma Glucose (FPG)

Structured multidisciplinary case management shows a strong positive evidence signal for improving Fasting Plasma Glucose (FPG) across the studied comparisons.

ConsistencyScore™
consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Continuous glucose monitoring

Continuous glucose monitoring → Time above range

Continuous glucose monitoring does not show benefit for Time above range in the available evidence and may be associated with worse results.

ConsistencyScore™
mixed
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Insulin therapy

Insulin therapy → Blood glucose

Insulin therapy has a small positive evidence signal for Blood glucose, but the clinical interpretation is limited.

ConsistencyScore™
mixed
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Continuous glucose monitoring

Continuous glucose monitoring → Time below range

Continuous glucose monitoring has a small positive evidence signal for Time below range, but the clinical interpretation is limited.

ConsistencyScore™
mostly_consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Dipeptidyl peptidase-4 inhibitors

Dipeptidyl peptidase-4 inhibitors → Fasting Plasma Glucose (FPG)

Dipeptidyl peptidase-4 inhibitors shows a moderate positive evidence signal for improving Fasting Plasma Glucose (FPG) across the studied comparisons.

ConsistencyScore™
consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Metformin

Metformin → Fasting blood sugar (FBS)

Metformin shows a moderate positive evidence signal for improving Fasting blood sugar (FBS) across the studied comparisons.

ConsistencyScore™
mostly_consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Hybrid closed-loop system

Hybrid closed-loop system → Glucose variability

Hybrid closed-loop system has a small positive evidence signal for Glucose variability, but the clinical interpretation is limited.

ConsistencyScore™
mostly_consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Dapagliflozin

Dapagliflozin → Fasting Plasma Glucose (FPG)

Dapagliflozin shows a moderate positive evidence signal for improving Fasting Plasma Glucose (FPG) across the studied comparisons.

ConsistencyScore™
consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Lifestyle intervention for prediabetes

Lifestyle intervention for prediabetes → Fasting blood sugar (FBS)

Lifestyle intervention for prediabetes has a small positive evidence signal for Fasting blood sugar (FBS), but the clinical interpretation is limited.

ConsistencyScore™
mostly_consistent
Supporting studies: 4 supporting studies
Open dossier
Clinical Reference

Usual care

Usual care → Fasting Plasma Glucose (FPG)

Usual care has not shown a clear effect on Fasting Plasma Glucose (FPG) in the available evidence.

ConsistencyScore™
consistent
Supporting studies: 4 supporting studies
Open dossier
Clinical Reference

Resistance training

Resistance training → 2-hour plasma glucose

Resistance training has not shown a clear effect on 2-hour plasma glucose in the available evidence.

ConsistencyScore™
mixed
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Hybrid closed-loop system

Hybrid closed-loop system → Time above range

Hybrid closed-loop system shows a moderate positive evidence signal for improving Time above range across the studied comparisons.

ConsistencyScore™
consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Vitamin D supplementation

Vitamin D supplementation → Blood glucose

Vitamin D supplementation has a small positive evidence signal for Blood glucose, but the clinical interpretation is limited.

ConsistencyScore™
mostly_consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Continuous glucose monitoring

Continuous glucose monitoring → Time in range

Continuous glucose monitoring shows a moderate positive evidence signal for improving Time in range across the studied comparisons.

ConsistencyScore™
consistent
Supporting studies: 6 supporting studies
Open dossier
Clinical Reference

Metformin

Metformin → Glucose iAUC (OGTT)

Metformin shows a moderate positive evidence signal for improving Glucose iAUC (OGTT) across the studied comparisons.

ConsistencyScore™
consistent
Supporting studies: 4 supporting studies
Open dossier
Clinical Reference

Insulin therapy

Insulin therapy → Time in range

Insulin therapy has a small positive evidence signal for Time in range, but the clinical interpretation is limited.

ConsistencyScore™
mixed
Supporting studies: 4 supporting studies
Open dossier
Clinical Reference

Metformin

Metformin → Fasting Plasma Glucose (FPG)

Metformin shows a moderate positive evidence signal for improving Fasting Plasma Glucose (FPG) across the studied comparisons.

ConsistencyScore™
mostly_consistent
Supporting studies: 7 supporting studies
Open dossier
Clinical Reference

Lifestyle intervention for prediabetes

Lifestyle intervention for prediabetes → 2-hour plasma glucose

Lifestyle intervention for prediabetes has a small positive evidence signal for 2-hour plasma glucose, but the clinical interpretation is limited.

ConsistencyScore™
mostly_consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Vitamin D supplementation

Vitamin D supplementation → Fasting Plasma Glucose (FPG)

Vitamin D supplementation has not shown a clear effect on Fasting Plasma Glucose (FPG) in the available evidence.

ConsistencyScore™
consistent
Supporting studies: 3 supporting studies
Open dossier
Clinical Reference

Hybrid closed-loop system

Hybrid closed-loop system → Time in range

Hybrid closed-loop system shows a moderate positive evidence signal for improving Time in range across the studied comparisons.

ConsistencyScore™
consistent
Supporting studies: 9 supporting studies
Open dossier
Clinical Reference

Multi-species synbiotic (12 probiotic strains + FOS prebiotic)

Multi-species synbiotic (12 probiotic strains + FOS prebiotic) → Fasting Plasma Glucose (FPG)

Multi-species synbiotic (12 probiotic strains + FOS prebiotic) shows a strong positive evidence signal for improving Fasting Plasma Glucose (FPG) across the studied comparisons.

ConsistencyScore™
consistent
Supporting studies: 4 supporting studies
Open dossier