Supporting evidence

Semaglutide × Cardiovascular events

Authoritative support
3
Available studies
3
Unavailable support
0

Available supporting studies

Study 1 · Included

Oral semaglutide may improve cardiovascular event prevention in type 2 diabetes.

Rct

Comparison
Participants receiving oral semaglutide for primary prevention of cardiovascular events. · Participants receiving standard care for diabetes management.
Duration / follow-up
4 weeks
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Study 2 · Included

Semaglutide improves cardiovascular outcomes in high-risk patients

Rct

Comparison
Patients with type 2 diabetes and high risk chronic kidney disease receiving semaglutide. · Patients with type 2 diabetes and high risk chronic kidney disease receiving placebo.
Duration / follow-up
4 weeks

Relevant effects

Absolute change

42 · 0.029

Absolute change

52 · 0.01

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Study 3 · Included

Semaglutide may reduce cardiovascular events in non-diabetic patients.

Rct

Comparison
Participants received weekly injectable semaglutide 2.4 mg. · Participants received matching placebo.
Duration / follow-up
13 weeks

Relevant effect

Percent change

20

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