Weekly evidence changelog

What Changed This Week

Week of June 15-21, 2026Generated Jun 20, 2026

A weekly summary of studies, interventions, outcomes, and evidence relationships added to Dediabetes.

Changes reflect content added to Dediabetes during this week and may include studies published earlier.

14
New Studies
124
New Evidence Relationships
9
New Interventions
35
New Outcomes
0
Evidence Upgrades
0
Evidence Downgrades

Featured

Notable Changes

The most notable evidence graph changes detected in this weekly snapshot.

Notable Change

Acarbose -> 24-hour glucose

MedicationsGlycemic Control

Medications · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
Notable Change

Acarbose -> Glucose area under the curve (AUC)

MedicationsGlycemic Control

Medications · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
Notable Change

Acarbose -> Mean amplitude of glycemic excursions (MAGE)

MedicationsGlycemic Control

Medications · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence

New relationships

New Evidence Relationships

Showing the top 10 relationships first from content added to Dediabetes during this week.

New Evidence Relationship

Acarbose -> 24-hour glucose

MedicationsGlycemic Control

Medications · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
New Evidence Relationship

Acarbose -> Glucose area under the curve (AUC)

MedicationsGlycemic Control

Medications · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
New Evidence Relationship

Acarbose -> Mean amplitude of glycemic excursions (MAGE)

MedicationsGlycemic Control

Medications · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
New Evidence Relationship

Acarbose -> Postprandial blood glucose

MedicationsGlycemic Control

Medications · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
New Evidence Relationship

Acarbose -> Postprandial hypoglycemia incidence

MedicationsSafety

Medications · Safety

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
New Evidence Relationship

Arm Rotation with Walking Exercise -> Glucose iAUC (OGTT)

Physical ActivityGlycemic Control

Physical Activity · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
New Evidence Relationship

Arm Rotation with Walking Exercise -> HbA1c

Physical ActivityGlycemic Control

Physical Activity · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
New Evidence Relationship

Bifidobacterium longum subsp. longum BL21 -> Fasting blood sugar (FBS)

SupplementsGlycemic Control

Supplements · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
New Evidence Relationship

Bifidobacterium longum subsp. longum BL21 -> gut microbiota composition

SupplementsMetabolic Health

Supplements · Metabolic Health

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence
New Evidence Relationship

Bifidobacterium longum subsp. longum BL21 -> HbA1c

SupplementsGlycemic Control

Supplements · Glycemic Control

New evidence relationship detected from studies added this week.

1 new supporting study1 total supporting study
View evidence

Studies

New Studies Added

Studies added to the Dediabetes evidence system during this weekly snapshot.

RCTsAdded Jun 17, 2026

DSNF-Pro improves glycemic control in prediabetes

The study evaluated the effects of a diabetes-specific nutritional formula (DSNF-Pro) on postprandial glycemic control in prediabetic participants, finding significant reductions in glucose and c-peptide levels compared to a standard formula.

Diabetes-specific nutritional formula-pro (DSNF-Pro)C-peptide incremental area under the curve (iAUC)Glucose iAUC (OGTT)+1 more
RCTsAdded Jun 17, 2026

Semaglutide with Insulin Improves Diabetes Control and Kidney Health

This study evaluated the effects of semaglutide combined with insulin therapy on glycemic control and renal function in elderly patients with type 2 diabetes, finding significant improvements in several metabolic parameters.

Insulin therapy24-Hour Urinary Protein (24hUpr)Adverse events incidence+10 more
RCTsAdded Jun 19, 2026

BL21 probiotic improves glycemic control in type 2 diabetes patients

This study evaluated the efficacy and safety of Bifidobacterium longum subsp. longum BL21 as an adjunctive therapy to metformin in patients with type 2 diabetes, finding a significant reduction in HbA1c levels.

Bifidobacterium longum subsp. longum BL21PlaceboFasting blood sugar (FBS)+5 more
RCTsAdded Jun 19, 2026

Taichi training improves lung function and blood sugar control in diabetes

This study investigated the impact of 24-week Taichi training on pulmonary diffusion capacity and glycemic control in patients with Type 2 Diabetes Mellitus, finding significant improvements in several health markers.

Taichi plus resistance band trainingTaichi trainingEndothelial Nitric Oxide Synthase (eNOS)+10 more
RCTsAdded Jun 20, 2026

High-dose vitamin D3 does not improve insulin resistance in type 2 diabetes

This study investigated the effects of high-dose Vitamin D3 supplementation on insulin resistance and glycaemic control in adult males with type 2 diabetes. It found no significant differences in key metabolic outcomes between the intervention and placebo groups.

Vitamin D supplementationBMIFasting Plasma Glucose (FPG)+5 more

Entities

New Interventions & Outcomes

New intervention and outcome entities created during this weekly snapshot.

New Interventions

Acarbose plus voglibose therapyLow glycemic index treatment (LGIT)VogliboseDiabetes-specific nutritional formula-pro (DSNF-Pro)Arm Rotation with Walking ExerciseControl (Usual Activity)Standard nutritional formula (STNF)Bifidobacterium longum subsp. longum BL21Magnesium citrate

New Outcomes

Coefficient of variation24-hour glucoseGlucose area under the curve (AUC)C-peptide incremental area under the curve (iAUC)24-Hour Urinary Protein (24hUpr)Endothelin-1 (ET-1)Fasting Plasma Glucose (FPG)Homeostatic Model Assessment of Beta-cell function (HOMA-β)Nitric Oxide (NO)HbA1c levels (Placebo)gut microbiota compositionlipid profilesAnxiety (Placebo)Depression (Placebo)Stress (Placebo)Alanine Aminotransferase (ALT)Tumor Necrosis Factor-alpha (TNF-α)von Willebrand Factor (vWF)Endothelial Nitric Oxide Synthase (eNOS)Intercellular Adhesion Molecule-1 (ICAM-1)Interleukin-6 (IL-6)24-h urine magnesium excretionAbnormal stool frequencyCalciprotein crystallization (T 50)CalciumCarotid-femoral pulse wave velocity (cfPWV)Gastrointestinal symptoms frequencyHard or lumpy stoolsIncidence of macrosomiaMalondialdehyde (MDA)Neonatal birth weightOxidative stress markers (GSH)Retinol-Binding Protein 4 (RBP4)Serum 25-hydroxyvitamin DSerum magnesium

Evidence strength

Evidence Strength Changes

No evidence strength changes were detected this week.

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