Evidence Question

Does Semaglutide improve total daily insulin dose?

Related to: Adverse Events and Safety

Short answer

Semaglutide appears to improve total daily insulin dose.

Evidence at a glance

Evidence strength
Moderate Evidence
Supporting research
2 studys
Randomized trials
2 trials
Evidence updated
May 2026

Why do we say this?

Across 2 randomized trials, findings are consistent and showed an effect on total daily insulin dose with Semaglutide.

Context and limitations

  • Only a small number of supporting studies are available.

Explore the evidence

Supporting research

2 published studys