Evidence Question

Do SGLT2 inhibitors improve systolic blood pressure?

Related to: Cardiometabolic Risk

Short answer

SGLT2 inhibitors may improve systolic blood pressure.

Evidence at a glance

Evidence strength
Moderate Evidence
Supporting research
2 studys
Randomized trials
2 trials

Why do we say this?

Across 2 randomized trials, findings are mixed and showed an effect on systolic blood pressure with SGLT2 inhibitors.

Context and limitations

Some evidence reported benefits while other evidence found little or no effect.

  • Only a small number of supporting studies are available.

Explore the evidence

Supporting research

2 published studys