Evidence Question

Does Pentoxifylline improve estimated glomerular filtration rate?

Related to: Diabetic Kidney Disease

Short answer

Pentoxifylline may worsen estimated glomerular filtration rate or be associated with harm.

Evidence at a glance

Evidence strength
Emerging Evidence
Supporting research
1 study
Randomized trials
1 trial
Evidence updated
Jan 2026

Why do we say this?

Across 1 randomized trial, the evidence showed an effect on estimated glomerular filtration rate with Pentoxifylline.

Context and limitations

  • Only one supporting study is available.

Explore the evidence

Supporting research

1 published study