Carob concentrate may improve blood sugar markers in prediabetes
Conclusión Clave:
This trial tested a carob-based liquid concentrate in people with confirmed prediabetes. After 90 days, the supplement group had better HbA1c, glucose responses, and insulin-related markers than the placebo group, with no adverse effects reported.
Estudio de un Vistazo
Qué se estudió
A carob-derived liquid concentrate for glucose metabolism in adults with prediabetes
Participantes
Young Adult (19–39), Middle Aged (40-64)
Male, Female
with Prediabeteswith Insulin Resistance
Intervención
Carob liquid concentrate
Resultados
HbA1c, Fasting blood sugar (FBS), Postprandial glucose, Glucose iAUC (OGTT), Fasting insulin levels, Insulin resistance, Insulin sensitivity, Adverse events incidence
Financiamiento
No Patrocinado por la Industria
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Efectos Principales
Carob concentrate ↓ HbA1c and glucose levels versus placebo
Carob concentrate ↓ fasting insulin and insulin resistance markers within the experimental group
Carob concentrate ↓ OGTT glucose AUC, insulin AUC, and glucose peak within the experimental group
Resumen de Evidencia
| Intervention | Outcome | Measured Change | Study Effect |
|---|---|---|---|
 Carob liquid concentrate (Supplements) |  Adverse events incidence (Safety) | Decrease | Limited |
Carob liquid concentrate (Supplements) |  Fasting blood sugar (FBS) (Glycemic Control) | Decrease | Mixed |
Carob liquid concentrate (Supplements) |  Fasting insulin levels (Metabolic Health) | Decrease | Limited |
Carob liquid concentrate (Supplements) | Glucose iAUC (OGTT) (Glycemic Control) | Decrease | Mixed |
Carob liquid concentrate (Supplements) | HbA1c (Glycemic Control) | Decrease | Mixed |
Carob liquid concentrate (Supplements) | Insulin resistance (Metabolic Health) | Decrease | Limited |
Carob liquid concentrate (Supplements) | Insulin sensitivity (Metabolic Health) | Increase | Limited |
Carob liquid concentrate (Supplements) | Postprandial blood glucose (Glycemic Control) | Decrease | Mixed |
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Tener en Cuenta
- Small sample size with 52 total participants Short intervention duration of 90 days Methods and results excerpts were limited in the prompt, so several details remain unclear Findings focus on surrogate metabolic markers rather than diabetes incidence
Entre Líneas
- Small sample size with 52 total participants Short intervention duration of 90 days Methods and results excerpts were limited in the prompt, so several details remain unclear Findings focus on surrogate metabolic markers rather than diabetes incidence
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