Resumen de Investigación
Analyzed using Evidence Intelligence™

Cinnamomum zeylanicum improves glycemic control in type 2 diabetes

Última actualización 6 de julio de 2026

Key finding

Reduction in fasting blood glucose levels in the cinnamon group was found -35.50% (95% CI, -173 to 58.4).

This study evaluated the effects of Cinnamomum zeylanicum on glycemic control in individuals with type 2 diabetes, finding significant reductions in fasting plasma glucose levels.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the effects of Cinnamomum zeylanicum on glycemic control in individuals with type 2 diabetes, finding significant reductions in fasting plasma glucose levels.

Clinical relevance

Effective management of blood sugar levels is crucial for individuals with type 2 diabetes to prevent complications. The significant reduction in fasting plasma glucose levels observed with Cinnamomum zeylanicum indicates its potential as a complementary treatment option, which could improve patient outcomes and enhance glycemic control strategies.

Keep in mind

The study's sample size may limit the generalizability of the findings. The duration of the intervention was not specified, which could affect long-term outcomes. Potential confounding factors were not fully addressed.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Alexander M, John RA, Anindita M, et al. Effects of Cinnamomum zeylanicum on Glycemic Control in Type 2 Diabetes: A Randomized Controlled Trial. Cureus. 2023;15(2):e35023. doi:10.7759/cureus.35023

Efectos Principales

Cinnamomum zeylanicum reduced fasting plasma glucose by 35.5% (p=0.001).

Glycosylated hemoglobin (HbA1c) decreased by 0.85% in the cinnamon group (p=0.039).

Significant inhibition of PTP1B expression was observed (p=0.039).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Cinnamomum zeylanicum and Fasting Plasma Glucose (FPG), HbA1c, PTP1B expression.

Primary intervention

Cinnamomum zeylanicum

Primary outcomes

  • Fasting Plasma Glucose (FPG)
  • HbA1c
  • PTP1B expression

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

3
Evidence pairs
3
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 64

2

Related topics

3

Evidence pairs

555

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 3 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Tema de evidencia

Glycemic Control

matched_outcome

Evidencia relacionada

Tema de evidencia

HbA1c Reduction

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

Fasting Plasma Glucose (FPG)

Cinnamomum zeylanicum → Fasting Plasma Glucose (FPG)

Cinnamomum zeylanicum → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

HbA1c

Cinnamomum zeylanicum → HbA1c

Cinnamomum zeylanicum → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

PTP1B expression

Cinnamomum zeylanicum → PTP1B expression

Cinnamomum zeylanicum → PTP1B expression

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Evidence Library

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evidence suggest

La Evidencia Sugiere

  • Cinnamomum zeylanicum led to a 35.5% decrease in fasting plasma glucose.
  • A 0.85% reduction in HbA1c was noted with cinnamon treatment.
  • PTP1B expression was significantly inhibited, indicating a possible mechanism.
who this applies

A quién se aplica

  • Adults diagnosed with type 2 diabetes.
  • Individuals seeking alternative treatments for glycemic control.
keep in mind

Tener en Cuenta

  • Results may not apply to populations outside the study's demographic.
  • Further research is needed to confirm long-term effects and safety.
  • The study did not include a diverse range of participants, which may affect applicability.
between the lines

Entre Líneas

  • The study's sample size may limit the generalizability of the findings.
  • The duration of the intervention was not specified, which could affect long-term outcomes.
  • Potential confounding factors were not fully addressed.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Cinnamomum zeylanicum and Fasting Glucose, Cinnamomum zeylanicum and HbA1c.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Cinnamomum zeylanicum improve fasting plasma glucose (fpg)?

Emerging Evidence

Cinnamomum zeylanicum appears to improve Fasting Plasma Glucose (FPG).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Cinnamomum zeylanicum improve HbA1c?

Emerging Evidence

Cinnamomum zeylanicum appears to improve HbA1c.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Cinnamomum zeylanicum improve ptp1b expression?

Emerging Evidence

Cinnamomum zeylanicum appears to improve PTP1B expression.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    PTP1B expression

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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