Resumen de Investigación
Analyzed using Evidence Intelligence™

CPAP therapy shows little effect on glycaemic control in type 2 diabetes

Última actualización 11 de julio de 2026

Key finding

Fasting blood glucose increased by 0.2 mmol/L (P = .02) in the CPAP group.

This study investigated the impact of CPAP therapy on glycaemic control in patients with type 2 diabetes and obstructive sleep apnoea, finding no significant changes in most glucose metrics.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study investigated the impact of CPAP therapy on glycaemic control in patients with type 2 diabetes and obstructive sleep apnoea, finding no significant changes in most glucose metrics.

Clinical relevance

Understanding the effects of CPAP therapy on glycaemic control is crucial for managing patients with both obstructive sleep apnoea and type 2 diabetes. The findings suggest that while CPAP may have some benefits, it does not significantly improve overall blood sugar control, which is essential for preventing diabetes-related complications.

Keep in mind

Limited sample size may affect generalizability. Short duration of the study may not capture long-term effects. Only one intervention (CPAP) was tested, limiting comparative analysis.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Anne MB, Christoffer K, Peter LK, et al. The effect of continuous positive airway pressure therapy on glycaemic control in patients with type 2 diabetes and obstructive sleep apnoea: A randomized controlled trial. Endocrinology, Diabetes & Metabolism. 2020;4(2):e00148. doi:10.1002/edm2.148

Efectos Principales

HbA1c decreased by 0.7 mmol/mol (0.07%; P = .8) in the CPAP group.

Fasting plasma glucose increased by 0.2 mmol/L (P = .02) in the CPAP group.

No significant changes were found in average glucose levels.

No significant changes were found in time in glucose range.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Continuous Positive Airway Pressure (CPAP) and Average glucose levels measured over 24 hours, Coefficient of variation, Fasting Plasma Glucose (FPG), and 4 more.

Primary intervention

Continuous Positive Airway Pressure (CPAP)

Primary outcomes

  • Average glucose levels measured over 24 hours
  • Coefficient of variation
  • Fasting Plasma Glucose (FPG)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 64

2

Related topics

7

Evidence pairs

376

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Tema de evidencia

Glycemic Control

matched_outcome

Evidencia relacionada

Tema de evidencia

HbA1c Reduction

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

Average glucose levels measured over 24 hours

Continuous Positive Airway Pressure (CPAP) → Average glucose levels measured over 24 hours

Continuous Positive Airway Pressure (CPAP) → Average glucose levels measured over 24 hours

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Coefficient of variation

Continuous Positive Airway Pressure (CPAP) → Coefficient of variation

Continuous Positive Airway Pressure (CPAP) → Coefficient of variation

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting Plasma Glucose (FPG)

Continuous Positive Airway Pressure (CPAP) → Fasting Plasma Glucose (FPG)

Continuous Positive Airway Pressure (CPAP) → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
25
Negative
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

HbA1c

Continuous Positive Airway Pressure (CPAP) → HbA1c

Continuous Positive Airway Pressure (CPAP) → HbA1c

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Time in range

Continuous Positive Airway Pressure (CPAP) → Time in range

Continuous Positive Airway Pressure (CPAP) → Time in range

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Time spent in hyperglycaemic range

Continuous Positive Airway Pressure (CPAP) → Time spent in hyperglycaemic range

Continuous Positive Airway Pressure (CPAP) → Time spent in hyperglycaemic range

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Time spent in hypoglycaemic range

Continuous Positive Airway Pressure (CPAP) → Time spent in hypoglycaemic range

Continuous Positive Airway Pressure (CPAP) → Time spent in hypoglycaemic range

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

La Evidencia Sugiere

  • HbA1c showed a minor decrease of 0.7 mmol/mol in the CPAP group.
  • Fasting plasma glucose increased by 0.2 mmol/L, indicating a potential concern.
  • Most other glycaemic control measures showed no significant changes.
who this applies

A quién se aplica

  • Adults diagnosed with type 2 diabetes.
  • Patients experiencing obstructive sleep apnoea.
keep in mind

Tener en Cuenta

  • Results may not apply to populations outside the study sample.
  • The study did not assess long-term effects of CPAP therapy.
  • Further research is needed to explore the relationship between CPAP and glycaemic control.
between the lines

Entre Líneas

  • Limited sample size may affect generalizability.
  • Short duration of the study may not capture long-term effects.
  • Only one intervention (CPAP) was tested, limiting comparative analysis.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Continuous Positive Airway Pressure (CPAP) and HbA1c, Continuous Positive Airway Pressure (CPAP) and CGM Time in Range.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Continuous Positive Airway Pressure (CPAP) improve HbA1c?

Moderate Evidence

Continuous Positive Airway Pressure (CPAP) may improve HbA1c.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Continuous Positive Airway Pressure (CPAP) improve time in range?

Moderate Evidence

Continuous Positive Airway Pressure (CPAP) may improve Time in range.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Time in range

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Continuous Positive Airway Pressure (CPAP) improve average glucose levels measured over 24 hours?

Emerging Evidence

Current evidence does not show a clear benefit of Continuous Positive Airway Pressure (CPAP) for Average glucose levels measured over 24 hours.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Average glucose levels measured over 24 hours

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Continuous Positive Airway Pressure (CPAP) improve coefficient of variation?

Emerging Evidence

Current evidence does not show a clear benefit of Continuous Positive Airway Pressure (CPAP) for Coefficient of variation.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Coefficient of variation

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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