Resumen de Investigación
Analyzed using Evidence Intelligence™

Dietary supplement may decrease fasting plasma glucose in prediabetic adults

Última actualización 18 de julio de 2026

Key finding

FPG decreased compared to placebo (-0.24±0.50 vs +0.12±0.59 mmol/L, respectively, p = 0.02)

This study examined the effects of a dietary supplement containing cinnamon, chromium, and carnosine on fasting plasma glucose in prediabetic individuals, finding a significant reduction in fasting plasma glucose levels compared to placebo.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Extended (5–20+ y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study examined the effects of a dietary supplement containing cinnamon, chromium, and carnosine on fasting plasma glucose in prediabetic individuals, finding a significant reduction in fasting plasma glucose levels compared to placebo.

Clinical relevance

These findings are clinically significant as they suggest that dietary supplementation may be a viable strategy for managing fasting plasma glucose levels in prediabetic individuals, potentially reducing the risk of progression to type 2 diabetes. Understanding the impact of such supplements can help healthcare providers offer more comprehensive dietary recommendations to patients at risk.

Keep in mind

The study did not report on long-term effects of the dietary supplement. Sample size and demographic characteristics may limit generalizability. No significant changes in HbA1c raise questions about clinical relevance.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Yuejun L, Aurélie C, Camille V, et al. Effects of a Dietary Supplement Containing Cinnamon, Chromium, and Carnosine on Fasting Plasma Glucose in Prediabetic Subjects. PLOS ONE. 2015;10(9):e0138646. doi:10.1371/journal.pone.0138646

Efectos Principales

Fasting plasma glucose decreased by -0.24 mmol/L in the supplement group compared to placebo (p = 0.02).

Fat-free mass (%) increased with the dietary supplement compared to placebo (p = 0.02).

No significant changes were observed in HbA1c levels.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Dietary supplement containing cinnamon, chromium and carnosine and Fasting Plasma Glucose (FPG), HbA1c, Lean body mass.

Primary intervention

Dietary supplement containing cinnamon, chromium and carnosine

Primary outcomes

  • Fasting Plasma Glucose (FPG)
  • HbA1c
  • Lean body mass

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

3
Evidence pairs
3
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

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Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

3

Related topics

3

Evidence pairs

732

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 3 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Tema de evidencia

Glycemic Control

matched_outcome

Evidencia relacionada

Tema de evidencia

HbA1c Reduction

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

Fasting Plasma Glucose (FPG)

Dietary supplement containing cinnamon, chromium and carnosine → Fasting Plasma Glucose (FPG)

Dietary supplement containing cinnamon, chromium and carnosine → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

HbA1c

Dietary supplement containing cinnamon, chromium and carnosine → HbA1c

Dietary supplement containing cinnamon, chromium and carnosine → HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Lean body mass

Dietary supplement containing cinnamon, chromium and carnosine → Lean body mass

Dietary supplement containing cinnamon, chromium and carnosine → Lean body mass

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Evidence Library

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evidence suggest

La Evidencia Sugiere

  • Fasting plasma glucose decreased by -0.24 mmol/L with the dietary supplement.
  • Fat-free mass increased significantly with the supplement (p = 0.02).
  • No significant changes in HbA1c were detected.
who this applies

A quién se aplica

  • Adults diagnosed with prediabetes.
  • Individuals looking to manage fasting plasma glucose levels.
keep in mind

Tener en Cuenta

  • The study's findings are based on a specific dietary supplement formulation.
  • Results may not be applicable to all populations or dietary contexts.
  • Further research is needed to confirm long-term effects and benefits.
between the lines

Entre Líneas

  • The study did not report on long-term effects of the dietary supplement.
  • Sample size and demographic characteristics may limit generalizability.
  • No significant changes in HbA1c raise questions about clinical relevance.

Evidence Library

Build your evidence library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Dietary supplement containing cinnamon, chromium and carnosine and Fasting Glucose, Dietary supplement containing cinnamon, chromium and carnosine and HbA1c.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Dietary supplement containing cinnamon, chromium and carnosine improve fasting plasma glucose (fpg)?

Emerging Evidence

Dietary supplement containing cinnamon, chromium and carnosine appears to improve Fasting Plasma Glucose (FPG).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Dietary supplement containing cinnamon, chromium and carnosine affect lean body mass?

Emerging Evidence

Dietary supplement containing cinnamon, chromium and carnosine appears to improve Lean body mass.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Lean body mass

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Dietary supplement containing cinnamon, chromium and carnosine improve HbA1c?

Emerging Evidence

Current evidence does not show a clear benefit of Dietary supplement containing cinnamon, chromium and carnosine for HbA1c.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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