Resumen de Investigación
Analyzed using Evidence Intelligence™

Dulaglutide may improve weight loss in obese patients with diabetes

Última actualización 4 de julio de 2026

Key finding

The patient achieved a weight loss of 40 kg (−21%) over 6 months.

This study evaluated the effects of Dulaglutide on weight loss in a morbidly obese patient with type 2 diabetes, resulting in significant weight reduction and improved glycemic control.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

Non-randomized CT

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the effects of Dulaglutide on weight loss in a morbidly obese patient with type 2 diabetes, resulting in significant weight reduction and improved glycemic control.

Clinical relevance

This study highlights the potential of Dulaglutide as a therapeutic option for weight management in patients with type 2 diabetes, addressing a critical aspect of diabetes care. Effective weight loss can lead to improved health outcomes and reduced complications associated with obesity and diabetes.

Keep in mind

Single participant limits generalizability. Non-randomized design may introduce bias. No long-term follow-up data available.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Sohail B, Sahil B, Grishma S, et al. Dulaglutide for Weight Loss in a Morbidly Obese Patient with Type 2 Diabetes. Clinical Case Reports. 2024;12(9):e9403. doi:10.1002/ccr3.9403

Efectos Principales

Weight loss of 40 kg (−21%) over 6 months.

BMI decreased by 10.3 kg/m² over 6 months.

Daily caloric intake reduced from 6924 to 2538.9 calories.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Dulaglutide and BMI, Body weight, Caloric intake, and 2 more.

Primary intervention

Dulaglutide

Primary outcomes

  • BMI
  • Body weight
  • Caloric intake

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

5
Evidence pairs
5
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

3

Related topics

5

Evidence pairs

481

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 5 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Relación de evidencia

GLP-1 Receptor Agonists and Body Weight

Evidencia relacionada

Relación de evidencia

GLP-1 Receptor Agonists and Body Mass Index

Guardar evidencia

Relación de evidencia

GLP-1 Receptor Agonists and Gastrointestinal Adverse Events

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

BMI

Dulaglutide → BMI

Dulaglutide → BMI

Evidence Intelligence™
EvidenceScore™
75
Strong
ImpactScore™
65
Slightly Positive
ConsistencyScore™
67
generally_consistent
Estudios de apoyo: Basado en 3 estudios
Add to Evidence Tracker

Body weight

Dulaglutide → Body weight

Dulaglutide → Body weight

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
76
Positive
ConsistencyScore™
100
consistent
Estudios de apoyo: Basado en 2 estudios
Add to Evidence Tracker

Caloric intake

Dulaglutide → Caloric intake

Dulaglutide → Caloric intake

Evidence Intelligence™
EvidenceScore™
58
Emerging
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Gastrointestinal disorders incidence

Dulaglutide → Gastrointestinal disorders incidence

Dulaglutide → Gastrointestinal disorders incidence

Evidence Intelligence™
EvidenceScore™
58
Emerging
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Time to glycemic target

Dulaglutide → Time to glycemic target

Dulaglutide → Time to glycemic target

Evidence Intelligence™
EvidenceScore™
58
Emerging
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Evidence Library

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evidence suggest

La Evidencia Sugiere

  • 40 kg weight loss observed in 6 months.
  • 10.3 kg/m² reduction in BMI recorded.
  • Daily caloric intake decreased by 4385.1 calories.
who this applies

A quién se aplica

  • Morbidly obese adults with type 2 diabetes.
  • Patients seeking pharmacological weight loss options.
keep in mind

Tener en Cuenta

  • Results are based on a single case study.
  • Further research needed to confirm findings.
  • Effectiveness in broader populations remains unclear.
between the lines

Entre Líneas

  • Single participant limits generalizability.
  • Non-randomized design may introduce bias.
  • No long-term follow-up data available.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on GLP-1 Receptor Agonists and Body Mass Index, GLP-1 Receptor Agonists and Body Weight.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does GLP-1 Receptor Agonists affect body weight?

Strong Evidence

GLP-1 Receptor Agonists appears to improve Body Weight.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Body weight

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on 30 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
30 supporting studiesUpdated: Jul 2026

Does GLP-1 Receptor Agonists affect body mass index?

Strong Evidence

GLP-1 Receptor Agonists may improve Body Mass Index.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    BMI

    EvidenceScore™ Strong | EvidenceScore™ 75.4 | weak positive | ConsistencyScore™ Generally Consistent | 1 study

Why this answer: This answer is based on 15 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
15 supporting studiesUpdated: Jul 2026

Does GLP-1 Receptor Agonists affect gastrointestinal adverse events?

Strong Evidence

GLP-1 Receptor Agonists may worsen Gastrointestinal Adverse Events or be associated with harm.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    Gastrointestinal disorders incidence

    EvidenceScore™ Emerging | EvidenceScore™ 58.5 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 6 supporting studies and existing graph evidence signals.

Limitations

  • Population details are unavailable.
6 supporting studiesUpdated: Jul 2026

Does GLP-1 Receptor Agonists improve cgm time in range?

Moderate Evidence

GLP-1 Receptor Agonists may improve CGM Time in Range.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Time to glycemic target

    EvidenceScore™ Emerging | EvidenceScore™ 58.5 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 3 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
3 supporting studiesUpdated: Jul 2026
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