Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 3 studies
- ImpactScore™
- 83
- Positive
- ConsistencyScore™
- 67
- generally_consistent
Estudios de apoyo: Basado en 3 estudios
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Exercise improves insulin resistance and diabetes risk
Última actualización 12 de septiembre de 2026
Key finding
LP-IR improved by -4.4 ± 8.2.
This study evaluated the effects of multiple exercise interventions on lipoprotein insulin resistance and diabetes risk indices, finding improvements across various interventions.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Extended (5–20+ y)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the effects of multiple exercise interventions on lipoprotein insulin resistance and diabetes risk indices, finding improvements across various interventions.
Clinical relevance
These findings highlight the importance of exercise in reducing diabetes risk and improving metabolic health. As diabetes prevalence continues to rise, understanding effective interventions like exercise can aid healthcare providers in developing strategies to combat this public health issue. Encouraging physical activity may lead to better health outcomes for individuals at risk of diabetes.
Keep in mind
Effectiveness of each intervention remains unclear. Sample size and demographic details not specified. Potential confounding factors not measured.
Published in
Referencia de la Revista
Publication details and source links for this paper.
Leanna MR, Cris AS, Alyssa MZ, et al. Multiple Exercise Interventions Improve Lipoprotein Insulin Resistance Index and Diabetes Risk Index. Frontiers in Physiology. 2021;12:626142. doi:10.3389/fphys.2021.626142
Efectos Principales
LP-IR improved by -4.4 ± 8.2 following one intervention.
LP-IR improved by -12.4 ± 14.1 following another intervention.
Diabetes Risk Index improved by -2.8 ± 8.2.
Diabetes Risk Index improved by -8.3 ± 10.4.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Aerobic exercise, Lifestyle intervention for prediabetes, Resistance training and Insulin resistance, Diabetes Risk Index.
This study contributes evidence to
Primary intervention
Aerobic exercise
Primary outcomes
- Insulin resistance
- Diabetes Risk Index
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
3
Evidence pairs
3
Relationships
3
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
3
Related topics
3
Evidence pairs
825
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 3 evidence relationships
- Includes primary outcome data
- Linked to 3 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Relación de evidencia
Aerobic Exercise and Insulin Resistance
Evidencia relacionada
Tema de evidencia
Prediabetes
Guardar evidencia
Tema de evidencia
Insulin Resistance
Guardar evidencia
Core evidence
Study findings
The primary outcomes reported in this study.
Diabetes Risk Index
Lifestyle intervention for prediabetes → Diabetes Risk Index
Lifestyle intervention for prediabetes → Diabetes Risk Index
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerDiabetes Risk Index
Resistance training → Diabetes Risk Index
Resistance training → Diabetes Risk Index
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Library
Build your evidence library
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La Evidencia Sugiere
- LP-IR decreased by -4.4 and -12.4 units.
- Diabetes Risk Index decreased by -2.8 and -8.3 units.
- Multiple exercise types showed potential benefits for metabolic health.
A quién se aplica
- Adults at risk of developing diabetes.
- Individuals seeking to improve metabolic health through exercise.
Tener en Cuenta
- Results may not be generalizable to all populations.
- Further research needed to clarify effectiveness of interventions.
- Study design limits understanding of long-term impacts.
Entre Líneas
- Effectiveness of each intervention remains unclear.
- Sample size and demographic details not specified.
- Potential confounding factors not measured.
Evidence Library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Lifestyle intervention for prediabetes and Insulin Resistance, Aerobic Exercise and Insulin Resistance.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Behavioral & Lifestyle
Lifestyle intervention for prediabetes → Insulin Resistance
Behavioral & Lifestyle
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 4 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 75
- consistent
Estudios de apoyo: Basado en 4 estudios
View evidencePhysical Activity
Aerobic Exercise → Insulin Resistance
Physical Activity
Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 3 studies
- ImpactScore™
- 83
- Positive
- ConsistencyScore™
- 67
- generally_consistent
Estudios de apoyo: Basado en 3 estudios
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
Insulin Resistance Evidence Hub
All studies measuring Insulin Resistance
4 studies
outcome_hubMeasures Insulin Resistance as a key outcome.
Lifestyle intervention for prediabetes Evidence Hub
All studies on Lifestyle intervention for prediabetes
4 studies
intervention_hubContributes to Lifestyle intervention for prediabetes evidence base.
Aerobic Exercise Evidence Hub
All studies on Aerobic Exercise
3 studies
intervention_hubContributes to Aerobic Exercise evidence base.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Lifestyle intervention for prediabetes and Insulin resistance
Intervention: Lifestyle intervention for prediabetesOutcome: Insulin resistance
4 results
All studies on Aerobic exercise and Insulin resistance
Intervention: Aerobic exerciseOutcome: Insulin resistance
3 results
All studies on Lifestyle intervention for prediabetes
Intervention: Lifestyle intervention for prediabetes
4 results
All studies on Aerobic exercise
Intervention: Aerobic exercise
3 results
All studies measuring Insulin resistance
Outcome: Insulin resistance
4 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Aerobic Exercise improve insulin resistance?
Strong Evidence
Aerobic Exercise may improve insulin resistance.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Insulin resistance
EvidenceScore™ Strong | EvidenceScore™ 79.0 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on 5 supporting studies with consistent results and a positive effect signal.
Does Lifestyle intervention for prediabetes reduce diabetes risk index?
Emerging Evidence
Lifestyle intervention for prediabetes appears to reduce diabetes risk index.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Diabetes Risk Index
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Resistance training reduce diabetes risk index?
Emerging Evidence
Resistance training appears to reduce diabetes risk index.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Diabetes Risk Index
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Next steps
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Evidence topics
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Related research
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