Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Glutamine supplementation may decrease glycaemia in type 2 diabetes.
Última actualización 5 de julio de 2026
Key finding
HbA1c decreased (P = 0.007)
Daily oral supplementation of glutamine with or without sitagliptin in well-controlled type 2 diabetes patients.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
Guarda investigacion, organiza estudios y vuelve a encontrar evidencia importante rapidamente.
Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
Daily oral supplementation of glutamine with or without sitagliptin in well-controlled type 2 diabetes patients.
Clinical relevance
This study evaluated Daily oral supplementation of glutamine with or without sitagliptin in well-controlled type 2 diabetes patients.
Keep in mind
Limitations were not clearly described in the extracted text.
Published in
Referencia de la Revista
Publication details and source links for this paper.
Dorit S, Donald JC, Fiona MG, et al. Daily oral supplementation of glutamine with or without sitagliptin decreases glycaemia in type 2 diabetes patients. PLoS ONE. 2014;9(11):e113366. doi:10.1371/journal.pone.0113366
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Glutamine with Sitagliptin and Albuminuria, Blood urea nitrogen (BUN), Body weight, and 8 more.
This study contributes evidence to
Primary intervention
Glutamine with Sitagliptin
Primary outcomes
- Albuminuria
- Blood urea nitrogen (BUN)
- Body weight
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
11
Evidence pairs
11
Relationships
3
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
3
Related topics
11
Evidence pairs
505
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 11 evidence relationships
- Includes primary outcome data
- Linked to 3 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Agrega evidencia relacionada a tu Evidence Tracker
Guarda estudios y paginas de evidencia, organiza tu Evidence Tracker y manten en un solo lugar la investigacion que te importa.
Evidencia principal
Relación de evidencia
DPP-4 Inhibitors and HbA1c
Evidencia relacionada
Relación de evidencia
DPP-4 Inhibitors and Body Weight
Guardar evidencia
Relación de evidencia
DPP-4 Inhibitors and Kidney Function
Guardar evidencia
Core evidence
Study findings
The primary outcomes reported in this study.
Blood urea nitrogen (BUN)
Glutamine with Sitagliptin → Blood urea nitrogen (BUN)
Glutamine with Sitagliptin → Blood urea nitrogen (BUN)
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEstimated glomerular filtration rate
Glutamine with Sitagliptin → Estimated glomerular filtration rate
Glutamine with Sitagliptin → Estimated glomerular filtration rate
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerPlasma Electrolytes
Glutamine with Sitagliptin → Plasma Electrolytes
Glutamine with Sitagliptin → Plasma Electrolytes
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerRed Blood Cells
Glutamine with Sitagliptin → Red Blood Cells
Glutamine with Sitagliptin → Red Blood Cells
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerSerum creatinine
Glutamine with Sitagliptin → Serum creatinine
Glutamine with Sitagliptin → Serum creatinine
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on DPP-4 Inhibitors and Kidney Function, DPP-4 Inhibitors and Blood urea nitrogen (BUN).
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Medications
DPP-4 Inhibitors → Kidney Function
Medications
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceMedications
DPP-4 Inhibitors → Blood urea nitrogen (BUN)
Medications
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceMedications
DPP-4 Inhibitors → Body Weight
Medications
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
Blood urea nitrogen (BUN) Evidence Hub
All studies measuring Blood urea nitrogen (BUN)
1 studies
outcome_hubMeasures Blood urea nitrogen (BUN) as a key outcome.
Body Weight Evidence Hub
All studies measuring Body Weight
1 studies
outcome_hubMeasures Body Weight as a key outcome.
DPP-4 Inhibitors Evidence Hub
All studies on DPP-4 Inhibitors
1 studies
intervention_hubContributes to DPP-4 Inhibitors evidence base.
Kidney Function Evidence Hub
All studies measuring Kidney Function
1 studies
outcome_hubMeasures Kidney Function as a key outcome.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Glutamine with Sitagliptin and Albuminuria
Intervention: Glutamine with SitagliptinOutcome: Albuminuria
1 results
All studies on Glutamine with Sitagliptin and Blood urea nitrogen (BUN)
Intervention: Glutamine with SitagliptinOutcome: Blood urea nitrogen (BUN)
1 results
All studies on Glutamine with Sitagliptin
Intervention: Glutamine with Sitagliptin
1 results
All studies measuring Albuminuria
Outcome: Albuminuria
1 results
All studies measuring Blood urea nitrogen (BUN)
Outcome: Blood urea nitrogen (BUN)
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does DPP-4 Inhibitors improve HbA1c?
Strong Evidence
DPP-4 Inhibitors appears to improve HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 10 supporting studies with consistent results and a positive effect signal.
Limitations
- Population details are unavailable.
Does DPP-4 Inhibitors affect body weight?
Strong Evidence
DPP-4 Inhibitors may improve Body Weight.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
Body weight
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 7 supporting studies with generally consistent results and a positive effect signal.
Limitations
- Population details are unavailable.
Does DPP-4 Inhibitors improve kidney function?
Moderate Evidence
DPP-4 Inhibitors appears to improve Kidney Function.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Evidence caveat: The available evidence reports mixed findings.
Ranked evidence signals
- 1
Albuminuria
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
- 2
Estimated glomerular filtration rate
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
- 3
Serum creatinine
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
- Only a small number of supporting studies are available.
- Population details are unavailable.
Does Glutamine with Sitagliptin improve fructosamine?
Emerging Evidence
Glutamine with Sitagliptin appears to improve Fructosamine.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Fructosamine
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Next steps
Continue your research
Choose a next path through related evidence topics, Evidence Explorer views, and research summaries.
Evidence topics
Follow the topics this study contributes to.
Explore in Evidence Explorer
Open broader Evidence Explorer views for this relationship.
Related research
Read related research summaries.
Dietary interventions improve glycemic control in pre-diabetic patientsEmpagliflozin improves heart function in type 2 diabetes patientsMediterranean ketogenic eating matched VLCKD for weight loss over 3 monthsMetabolomics score improves metabolic profiling in diabetesTime-Restricted Eating Improves Weight Loss in Type 2 Diabetes
Sin anuncios. Sin rastreo.
Centrada en la evidencia, no en la publicidad.
Segura y privada
Tus datos siempre están protegidos.
Siempre al día
Se agregan nuevos estudios todos los días.