Evidence Intelligence™
- EvidenceScore™
- 86
- Strong
- ImpactScore™
- 82
- Positive
- ConsistencyScore™
- 65
- generally_consistent
Estudios de apoyo: Basado en 24 estudios
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Low-Carbohydrate Diet May Help Weight Loss in Pre-Diabetes
Última actualización 22 de agosto de 2026
Key finding
Mean weight loss in kilogram was 4.3 (SD 4.8) at 6 months.
This study evaluated the feasibility and effectiveness of a Very Low-Carbohydrate Diet (VLCD) for weight loss in individuals with pre-diabetes.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Long-Term (1–5 y)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the feasibility and effectiveness of a Very Low-Carbohydrate Diet (VLCD) for weight loss in individuals with pre-diabetes.
Clinical relevance
Weight management is crucial for individuals with pre-diabetes to prevent progression to type 2 diabetes. This study suggests that a VLCD could be an effective dietary approach, potentially leading to significant weight loss and improved health outcomes.
Keep in mind
Small sample size may limit generalizability. Lack of long-term follow-up data. Unclear effectiveness due to insufficient statistical analysis.
Published in
Referencia de la Revista
Publication details and source links for this paper.
Dina HG, Laura S, Kaitlyn P, et al. An LC-DPP is feasible, acceptable and may be an effective option to help individuals with pre-diabetes to lose weight. BMJ Open. 2020;10(1):e033397. doi:10.1136/bmjopen-2019-033397
Efectos Principales
Participants lost an average of 4.3 kg at 6 months and 4.9 kg at 12 months.
38% of participants achieved ≥5% weight loss at 12 months.
Mean attendance was 10.3 out of 16 weekly sessions.
HbA1c levels changed by -0.1% at 6 months and 0.06% at 12 months.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Low-carbohydrate diet and HbA1c, Mean attendance at lifestyle change program sessions, Proportion of participants achieving weight loss of 15% or more at 52 weeks, and 1 more.
This study contributes evidence to
Primary intervention
Low-carbohydrate diet
Primary outcomes
- HbA1c
- Mean attendance at lifestyle change program sessions
- Proportion of participants achieving weight loss of 15% or more at 52 weeks
Evidence topics
Primary intervention
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
4
Evidence pairs
4
Relationships
3
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
3
Related topics
4
Evidence pairs
1787
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 4 evidence relationships
- Includes primary outcome data
- Linked to 3 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Relación de evidencia
Low-Carbohydrate Diet Education and Body Weight
Evidencia relacionada
Relación de evidencia
Low-Carbohydrate Diet Education and HbA1c
Guardar evidencia
Relación de evidencia
Low-Carbohydrate Diet Education and Weight Loss Outcomes
Guardar evidencia
Core evidence
Study findings
The primary outcomes reported in this study.
Mean attendance at lifestyle change program sessions
Low-carbohydrate diet → Mean attendance at lifestyle change program sessions
Low-carbohydrate diet → Mean attendance at lifestyle change program sessions
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerProportion of participants achieving weight loss of 15% or more at 52 weeks
Low-carbohydrate diet → Proportion of participants achieving weight loss of 15% or more at 52 weeks
Low-carbohydrate diet → Proportion of participants achieving weight loss of 15% or more at 52 weeks
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 25
- Negative
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 2 estudios
Add to Evidence TrackerEvidence Library
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La Evidencia Sugiere
- Average weight loss of 4.3 kg at 6 months.
- 38% of participants lost ≥5% of their body weight.
- High attendance rates indicate good program acceptance.
A quién se aplica
- Adults diagnosed with pre-diabetes.
- Individuals seeking dietary interventions for weight loss.
Tener en Cuenta
- Results may not apply to larger or more diverse populations.
- Further research is needed to confirm long-term effectiveness.
- The study did not assess the impact of other lifestyle factors.
Entre Líneas
- Small sample size may limit generalizability.
- Lack of long-term follow-up data.
- Unclear effectiveness due to insufficient statistical analysis.
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Low-Carbohydrate Diet Education and HbA1c, Low-Carbohydrate Diet Education and Body Weight.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Low-Carbohydrate Diet Education → HbA1c
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- 86
- Strong
- ImpactScore™
- 82
- Positive
- ConsistencyScore™
- 65
- generally_consistent
Estudios de apoyo: Basado en 24 estudios
View evidenceDiet and Nutrition
Low-Carbohydrate Diet Education → Body Weight
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 2 estudios
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
HbA1c Evidence Hub
All studies measuring HbA1c
24 studies
outcome_hubMeasures HbA1c as a key outcome.
Low-Carbohydrate Diet Education Evidence Hub
All studies on Low-Carbohydrate Diet Education
24 studies
intervention_hubContributes to Low-Carbohydrate Diet Education evidence base.
Body Weight Evidence Hub
All studies measuring Body Weight
2 studies
outcome_hubMeasures Body Weight as a key outcome.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Low-carbohydrate diet and HbA1c
Intervention: Low-carbohydrate dietOutcome: HbA1c
24 results
All studies on Low-carbohydrate diet and Weight change
Intervention: Low-carbohydrate dietOutcome: Weight change
2 results
All studies on Low-carbohydrate diet
Intervention: Low-carbohydrate diet
24 results
All studies measuring HbA1c
Outcome: HbA1c
24 results
All studies measuring Weight change
Outcome: Weight change
2 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Low-Carbohydrate Diet Education affect body weight?
Strong Evidence
Low-Carbohydrate Diet Education appears to affect body weight.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Weight change
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 17 supporting studies with consistent results and a positive effect signal.
Does Low-Carbohydrate Diet Education lower HbA1c?
Strong Evidence
Low-Carbohydrate Diet Education may lower HbA1c.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 86.0 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on 28 supporting studies with generally consistent results and a positive effect signal.
Does Low-Carbohydrate Diet Education affect weight loss outcomes?
Emerging Evidence
Low-Carbohydrate Diet Education may have an unfavorable effect on weight loss outcomes or be associated with harm.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Proportion of participants achieving weight loss of 15% or more at 52 weeks
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | moderate negative | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Low-carbohydrate diet improve mean attendance at lifestyle change program sessions?
Emerging Evidence
Low-carbohydrate diet appears to improve mean attendance at lifestyle change program sessions.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Mean attendance at lifestyle change program sessions
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Next steps
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Evidence topics
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Explore in Evidence Explorer
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All studies on Low-carbohydrate diet and Weight changeAll studies on Low-carbohydrate diet and Proportion of participants achieving weight loss of 15% or more at 52 weeksAll studies on Low-carbohydrate diet and HbA1cAll studies on Low-carbohydrate diet and Mean attendance at lifestyle change program sessions
Related research
Read related research summaries.
Carbohydrate restriction lowers HbA1c but not β-cell function in T2DFood-based diet improves weight and glycaemic control in type 2 diabetesModerate Carbohydrate Diet Improves Glycemic Control in Type 1 DiabetesKetogenic diet improves weight and blood glucose control in type 2 diabetesLow-Carbohydrate Diet Improves Glycemic Control in Adolescents with Type 1 Diabetes
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