Resumen de Investigación
Analyzed using Evidence Intelligence™

Resistant starch shows little effect on glycemic control in type 2 diabetes

Última actualización 10 de septiembre de 2026

Key finding

HMS and NBS exhibited higher 24 h mean blood glucose values in comparison with DMS (p = 0.0001).

BL21 probiotic added to metformin in adults with type 2 diabetes.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Extended (5–20+ y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

BL21 probiotic added to metformin in adults with type 2 diabetes.

Clinical relevance

This study evaluated BL21 probiotic added to metformin in adults with type 2 diabetes.

Keep in mind

Limitations were not clearly described in the extracted text.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Yolanda A, Jorge LB, Carlos G, et al. Effects of Resistant Starch on Glycemic Control and Variability in Patients with Type 2 Diabetes. Nutrients. 2021;13(11):4052. doi:10.3390/nu13114052

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Digestible maize starch (DMS), High-amylose maize starch (HMS), Native banana starch (NBS) and Fasting Plasma Glucose (FPG), Indices of 24-hour glycemic variability, Blood glucose.

Primary intervention

Digestible maize starch (DMS)

Primary outcomes

  • Fasting Plasma Glucose (FPG)
  • Indices of 24-hour glycemic variability
  • Blood glucose

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

6
Evidence pairs
6
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 64

2

Related topics

6

Evidence pairs

886

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 6 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Tema de evidencia

Fasting Blood Glucose

matched_outcome

Evidencia relacionada

Tema de evidencia

Glycemic Control

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

Fasting Plasma Glucose (FPG)

Digestible maize starch (DMS) → Fasting Plasma Glucose (FPG)

Digestible maize starch (DMS) → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Indices of 24-hour glycemic variability

Digestible maize starch (DMS) → Indices of 24-hour glycemic variability

Digestible maize starch (DMS) → Indices of 24-hour glycemic variability

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Blood glucose

High-amylose maize starch (HMS) → Blood glucose

High-amylose maize starch (HMS) → Blood glucose

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
25
Negative
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Indices of 24-hour glycemic variability

High-amylose maize starch (HMS) → Indices of 24-hour glycemic variability

High-amylose maize starch (HMS) → Indices of 24-hour glycemic variability

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Blood glucose

Native banana starch (NBS) → Blood glucose

Native banana starch (NBS) → Blood glucose

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
25
Negative
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Indices of 24-hour glycemic variability

Native banana starch (NBS) → Indices of 24-hour glycemic variability

Native banana starch (NBS) → Indices of 24-hour glycemic variability

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Evidence Library

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Digestible maize starch (DMS) and Fasting Glucose, Digestible maize starch (DMS) and Indices of 24-hour glycemic variability.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Digestible maize starch (DMS) improve fasting plasma glucose (FPG)?

Emerging Evidence

Digestible maize starch (DMS) appears to improve fasting plasma glucose (FPG).

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Digestible maize starch (DMS) improve indices of 24-hour glycemic variability?

Emerging Evidence

Current evidence does not show a clear benefit of Digestible maize starch (DMS) for indices of 24-hour glycemic variability.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Indices of 24-hour glycemic variability

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does High-amylose maize starch (HMS) improve indices of 24-hour glycemic variability?

Emerging Evidence

Current evidence does not show a clear benefit of High-amylose maize starch (HMS) for indices of 24-hour glycemic variability.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Indices of 24-hour glycemic variability

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Native banana starch (NBS) improve indices of 24-hour glycemic variability?

Emerging Evidence

Current evidence does not show a clear benefit of Native banana starch (NBS) for indices of 24-hour glycemic variability.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Indices of 24-hour glycemic variability

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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