Evidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 4 studies
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 4 estudios
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Subgingival scaling may improve glycemic control in diabetes
Última actualización 18 de julio de 2026
Key finding
An 0.12 ± 0.08 increase of CD4+/CD8+ ratio was observed in SRP + OHI group when HbA1c ≥ 7.5%, which was significantly different to the control group (P = 0.040).
This study investigated the impact of subgingival scaling and root planing (SRP) combined with oral hygiene instruction (OHI) on glycemic control in type 2 diabetes patients with periodontitis, finding significant improvements in certain clinical measures.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the impact of subgingival scaling and root planing (SRP) combined with oral hygiene instruction (OHI) on glycemic control in type 2 diabetes patients with periodontitis, finding significant improvements in certain clinical measures.
Clinical relevance
Improving periodontal health is crucial for patients with diabetes, as it can influence overall health and glycemic control. This study highlights the potential benefits of dental interventions in managing diabetes-related complications, although further research is needed to clarify the relationship between periodontal treatment and glycemic control.
Keep in mind
The study's sample size may limit the generalizability of the findings. The lack of significant changes in HbA1c raises questions about the effectiveness of the interventions on glycemic control. The follow-up period of 6 months may not capture long-term effects.
Published in
Referencia de la Revista
Publication details and source links for this paper.
Yadan F, Zhikai L, Lan C, Linhua G. The effect of subgingival scaling and root planing on glycemic control in patients with type 2 diabetes and periodontitis. BMC Oral Health. 2025;25:1065. doi:10.1186/s12903-025-06462-9
Efectos Principales
SRP + OHI group showed a reduction in HbA1c of 0.22% compared to 0.07% in OHI group (P = 0.592).
CD4+/CD8+ ratio increased by 0.12 in SRP + OHI group when HbA1c ≥ 7.5% (P = 0.040).
BOP% significantly improved after treatment (P = 0.006).
Pocket depth significantly improved after treatment (P = 0.001).
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to SRP + OHI and Bleeding on probing, Change in CD4+/CD8+ Ratio, Clinical attachment level, and 3 more.
This study contributes evidence to
Primary intervention
SRP + OHI
Primary outcomes
- Bleeding on probing
- Change in CD4+/CD8+ Ratio
- Clinical attachment level
Evidence topics
Primary intervention
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
6
Evidence pairs
6
Relationships
1
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 63
1
Related topics
6
Evidence pairs
310
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 6 evidence relationships
- Includes primary outcome data
- Linked to 1 direct semantic evidence topic
Topic contributions
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
HbA1c Reduction
matched_outcome
Core evidence
Study findings
The primary outcomes reported in this study.
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- 84
- Strong
- ImpactScore™
- 83
- Positive
- ConsistencyScore™
- 67
- generally_consistent
Estudios de apoyo: Basado en 6 estudios
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 4 studies
- ImpactScore™
- 63
- Slightly Positive
- ConsistencyScore™
- 35
- mixed
Estudios de apoyo: Basado en 4 estudios
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- 83
- Strong
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 7 estudios
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 4 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Estudios de apoyo: Basado en 4 estudios
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
La Evidencia Sugiere
- SRP + OHI showed a 0.22% reduction in HbA1c, but not statistically significant.
- Significant improvement in CD4+/CD8+ ratio with SRP + OHI (P = 0.040).
- BOP% improved by 16.92% and pocket depth by 0.61 mm after treatment.
A quién se aplica
- Adults aged 30-65 with type 2 diabetes.
- Patients diagnosed with periodontitis.
Tener en Cuenta
- Results may not be applicable to populations outside the study demographics.
- The study did not measure long-term effects beyond 6 months.
- Further research is needed to establish a clear link between periodontal treatment and glycemic control.
Entre Líneas
- The study's sample size may limit the generalizability of the findings.
- The lack of significant changes in HbA1c raises questions about the effectiveness of the interventions on glycemic control.
- The follow-up period of 6 months may not capture long-term effects.
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on SRP + OHI and Clinical attachment level, SRP + OHI and Periodontal probing depth.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Procedures
SRP + OHI → Clinical attachment level
Procedures
Evidence Intelligence™
- EvidenceScore™
- 84
- Strong
- ImpactScore™
- 83
- Positive
- ConsistencyScore™
- 67
- generally_consistent
Estudios de apoyo: Basado en 6 estudios
View evidenceProcedures
SRP + OHI → Periodontal probing depth
Procedures
Evidence Intelligence™
- EvidenceScore™
- 83
- Strong
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 7 estudios
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
Periodontal probing depth Evidence Hub
All studies measuring Periodontal probing depth
7 studies
outcome_hubMeasures Periodontal probing depth as a key outcome.
Clinical attachment level Evidence Hub
All studies measuring Clinical attachment level
6 studies
outcome_hubMeasures Clinical attachment level as a key outcome.
SRP + OHI Evidence Hub
All studies on SRP + OHI
6 studies
intervention_hubContributes to SRP + OHI evidence base.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on SRP + OHI and Clinical attachment level
Intervention: SRP + OHIOutcome: Clinical attachment level
6 results
All studies on SRP + OHI and Periodontal probing depth
Intervention: SRP + OHIOutcome: Periodontal probing depth
7 results
All studies on SRP + OHI
Intervention: SRP + OHI
6 results
All studies measuring Clinical attachment level
Outcome: Clinical attachment level
6 results
All studies measuring Periodontal probing depth
Outcome: Periodontal probing depth
7 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does SRP + OHI improve clinical attachment level?
Strong Evidence
SRP + OHI may improve Clinical attachment level.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
- 1
Clinical attachment level
EvidenceScore™ Strong | EvidenceScore™ 83.6 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
Does SRP + OHI improve periodontal probing depth?
Strong Evidence
SRP + OHI appears to improve Periodontal probing depth.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Periodontal probing depth
EvidenceScore™ Strong | EvidenceScore™ 83.5 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
Does SRP + OHI improve bleeding on probing?
Strong Evidence
SRP + OHI appears to improve Bleeding on probing.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Bleeding on probing
EvidenceScore™ Strong | EvidenceScore™ 79.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
Does SRP + OHI improve plaque index (pi)?
Strong Evidence
SRP + OHI may improve Plaque Index (PI).
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Evidence caveat: The available evidence reports mixed findings.
Ranked evidence signals
- 1
Plaque Index (PI)
EvidenceScore™ Strong | EvidenceScore™ 79.0 | moderate positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
Next steps
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Related research
Read related research summaries.
Scaling and root planing improves glycemic control in T2DMAdditional toothbrushing improves oral health in type 2 diabetes patientsNSPT improves plaque index and glycemic control in diabetes.Adjunctive therapy improves periodontal outcomes in diabetes patientsCoenzyme Q10 improves periodontal health in diabetic patients
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