Última actualización 12 de julio de 2026
Key finding
Taurine supplementation significantly improved baPWV.
This study investigated the effects of taurine supplementation on blood pressure and vascular function in patients with type 2 diabetes, finding significant improvements in several key measures.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the effects of taurine supplementation on blood pressure and vascular function in patients with type 2 diabetes, finding significant improvements in several key measures.
These findings are clinically significant as they suggest that taurine supplementation may offer a simple and effective strategy for improving cardiovascular health in patients with type 2 diabetes, potentially reducing the risk of complications associated with the disease.
The study's sample size may limit the generalizability of the findings. The duration of supplementation was not specified, which could affect outcomes. The study did not assess long-term effects of taurine supplementation.
Published in
Publication details and source links for this paper.
Yingsha L, Qianran W, Yi L, et al. Taurine supplementation improves blood pressure and vascular dysfunction in patients with type 2 diabetes. iScience. 2025;28(6):112719. doi:10.1016/j.isci.2025.112719
Taurine supplementation reduced systolic blood pressure by 10 mmHg (p=0.001).
Brachial-ankle pulse wave velocity improved by 0.5 m/s (p=0.01).
Plasma hydrogen sulfide levels increased by 45 μmol/L (p=0.001).
Evidence network
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This study contributes evidence to Berberine and Brachial-ankle pulse wave velocity (baPWV), Change in plasma hydrogen sulfide levels after taurine supplementation, Change in plasma taurine levels after taurine supplementation, and 1 more.
This study contributes evidence to
Primary intervention
Berberine
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
4
Evidence pairs
196
Related studies
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
matched_outcome
Evidencia relacionada
Tema de evidencia
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Core evidence
The primary outcomes reported in this study.
Berberine → Brachial-ankle pulse wave velocity (baPWV)
Berberine → Brachial-ankle pulse wave velocity (baPWV)
Berberine → Change in plasma hydrogen sulfide levels after taurine supplementation
Berberine → Change in plasma hydrogen sulfide levels after taurine supplementation
Berberine → Change in plasma taurine levels after taurine supplementation
Berberine → Change in plasma taurine levels after taurine supplementation
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Berberine and Cardiovascular Outcomes, Berberine and Change in plasma hydrogen sulfide levels after taurine supplementation.
This study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Supplements
Curated evidence collections and hubs this study is part of.
All studies on Berberine
Contributes to Berberine evidence base.
All studies measuring Blood Pressure
Measures Blood Pressure as a key outcome.
All studies measuring Cardiovascular Outcomes
Measures Cardiovascular Outcomes as a key outcome.
All studies measuring Change in plasma hydrogen sulfide levels after taurine supplementation
Measures Change in plasma hydrogen sulfide levels after taurine supplementation as a key outcome.
Latest published studies
Published within the last 2 years.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Berberine appears to improve brachial-ankle pulse wave velocity (BAPWV).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Brachial-ankle pulse wave velocity (baPWV)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Berberine appears to improve change in plasma hydrogen sulfide levels after taurine supplementation.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Change in plasma hydrogen sulfide levels after taurine supplementation
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Berberine appears to improve change in plasma taurine levels after taurine supplementation.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Change in plasma taurine levels after taurine supplementation
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Berberine appears to improve systolic blood pressure.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Systolic blood pressure
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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