Resumen de Investigación
Analyzed using Evidence Intelligence™

Time-restricted eating may improve adherence in type 2 diabetes

Última actualización 17 de julio de 2026

Key finding

1,5-Anhydroglucitol levels increased significantly.

This pilot study investigated the effects of time-restricted eating on individuals with type 2 diabetes, revealing significant improvements in 1,5-Anhydroglucitol levels and hypoglycemia symptom recognition.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Long-Term (1–5 y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This pilot study investigated the effects of time-restricted eating on individuals with type 2 diabetes, revealing significant improvements in 1,5-Anhydroglucitol levels and hypoglycemia symptom recognition.

Clinical relevance

These findings suggest that time-restricted eating could be a beneficial dietary strategy for improving symptom awareness and certain metabolic markers in individuals with type 2 diabetes. Understanding these effects can help clinicians develop more effective dietary interventions for managing diabetes.

Keep in mind

Limited sample size may affect generalizability. Short duration of the study limits long-term conclusions. No significant changes in key metabolic outcomes.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Anne-Ditte T, Natasja B, Gitte SH, et al. Time-restricted eating in individuals with type 2 diabetes: a pilot study. Pilot and Feasibility Studies. 2025;11:135. doi:10.1186/s40814-025-01715-4

Efectos Principales

1,5-Anhydroglucitol levels increased significantly.

Participants showed improved recognition of hypoglycemia symptoms.

No significant change in 10-year ASCVD risk was observed.

No significant improvements in nocturnal glucose control were noted.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Time-Restricted Eating (TRE) and 1,5-Anhydroglucitol, 10-year ASCVD risk, Change in EsDQOL satisfaction score, and 11 more.

Primary intervention

Time-Restricted Eating (TRE)

Primary outcomes

  • 1,5-Anhydroglucitol
  • 10-year ASCVD risk
  • Change in EsDQOL satisfaction score

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

14
Evidence pairs
14
Relationships
5
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 72

5

Related topics

14

Evidence pairs

1065

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 14 evidence relationships
  • Includes primary outcome data
  • Linked to 5 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Tema de evidencia

Dietary Patterns

matched_intervention_and_outcome

Evidencia relacionada

Tema de evidencia

Glycemic Control

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

1,5-Anhydroglucitol

Time-Restricted Eating (TRE) → 1,5-Anhydroglucitol

Time-Restricted Eating (TRE) → 1,5-Anhydroglucitol

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

10-year ASCVD risk

Time-Restricted Eating (TRE) → 10-year ASCVD risk

Time-Restricted Eating (TRE) → 10-year ASCVD risk

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Change in EsDQOL satisfaction score

Time-Restricted Eating (TRE) → Change in EsDQOL satisfaction score

Time-Restricted Eating (TRE) → Change in EsDQOL satisfaction score

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Controlled attenuation parameter

Time-Restricted Eating (TRE) → Controlled attenuation parameter

Time-Restricted Eating (TRE) → Controlled attenuation parameter

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Depression score

Time-Restricted Eating (TRE) → Depression score

Time-Restricted Eating (TRE) → Depression score

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
50
Neutral
ConsistencyScore™
100
consistent
Estudios de apoyo: Basado en 2 estudios
Add to Evidence Tracker

Glucose iAUC (OGTT)

Time-Restricted Eating (TRE) → Glucose iAUC (OGTT)

Time-Restricted Eating (TRE) → Glucose iAUC (OGTT)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Glutathione (GSH)

Time-Restricted Eating (TRE) → Glutathione (GSH)

Time-Restricted Eating (TRE) → Glutathione (GSH)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

HbA1c

Time-Restricted Eating (TRE) → HbA1c

Time-Restricted Eating (TRE) → HbA1c

Evidence Intelligence™
EvidenceScore™
Strong
Score 79 · Based on 3 studies
ImpactScore™
67
Slightly Positive
ConsistencyScore™
67
generally_consistent
Estudios de apoyo: Basado en 3 estudios
Add to Evidence Tracker

Hypoglycemia symptom recognition ability

Time-Restricted Eating (TRE) → Hypoglycemia symptom recognition ability

Time-Restricted Eating (TRE) → Hypoglycemia symptom recognition ability

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Nocturnal glucose control

Time-Restricted Eating (TRE) → Nocturnal glucose control

Time-Restricted Eating (TRE) → Nocturnal glucose control

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Serum IL-8

Time-Restricted Eating (TRE) → Serum IL-8

Time-Restricted Eating (TRE) → Serum IL-8

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Serum MCP-1

Time-Restricted Eating (TRE) → Serum MCP-1

Time-Restricted Eating (TRE) → Serum MCP-1

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Time below range

Time-Restricted Eating (TRE) → Time below range

Time-Restricted Eating (TRE) → Time below range

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Time in range

Time-Restricted Eating (TRE) → Time in range

Time-Restricted Eating (TRE) → Time in range

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

evidence suggest

La Evidencia Sugiere

  • 1,5-Anhydroglucitol levels increased significantly.
  • Improved recognition of hypoglycemia symptoms was observed.
  • No significant changes in HbA1c or nocturnal glucose control.
who this applies

A quién se aplica

  • Adults diagnosed with type 2 diabetes.
  • Individuals interested in dietary interventions for diabetes management.
keep in mind

Tener en Cuenta

  • Results may not apply to all individuals with diabetes.
  • Further research is needed to confirm findings.
  • The study's short duration limits understanding of long-term effects.
between the lines

Entre Líneas

  • Limited sample size may affect generalizability.
  • Short duration of the study limits long-term conclusions.
  • No significant changes in key metabolic outcomes.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Time-Restricted Eating (TRE) and HbA1c, Time-Restricted Eating (TRE) and Mental Health.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Time-Restricted Eating (TRE) improve HbA1c?

Strong Evidence

Time-Restricted Eating (TRE) may improve HbA1c.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Strong | EvidenceScore™ 79.0 | weak positive | ConsistencyScore™ Generally Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Time-Restricted Eating (TRE) improve depression score?

Moderate Evidence

Current evidence does not show a clear benefit of Time-Restricted Eating (TRE) for Depression score.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Depression score

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | neutral | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Time-Restricted Eating (TRE) improve 1,5-anhydroglucitol?

Emerging Evidence

Time-Restricted Eating (TRE) appears to improve 1,5-Anhydroglucitol.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    1,5-Anhydroglucitol

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Time-Restricted Eating (TRE) affect hypoglycemia symptom recognition ability?

Emerging Evidence

Time-Restricted Eating (TRE) appears to improve Hypoglycemia symptom recognition ability.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Hypoglycemia symptom recognition ability

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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