- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Whey protein may lower blood glucose in type 2 diabetes
Última actualización 2 de septiembre de 2026
Key finding
WP stimulated insulin secretion (p<0.05)
This study investigated the effects of whey protein supplementation on glycemia in type 2 diabetes patients, finding significant improvements in insulin and GLP-1 secretion.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the effects of whey protein supplementation on glycemia in type 2 diabetes patients, finding significant improvements in insulin and GLP-1 secretion.
Clinical relevance
These findings are significant as they suggest that dietary interventions, such as whey protein supplementation, could be a valuable strategy for improving glycemic control in individuals with type 2 diabetes. This could lead to better management of diabetes and potentially reduce the risk of complications associated with poor glycemic control.
Keep in mind
The study's sample size may limit the generalizability of the findings. Effects of whey protein on glucose response varied based on individual baseline characteristics. No significant difference was found between whey protein and placebo on glucose response (p=0.097).
Published in
Referencia de la Revista
Publication details and source links for this paper.
Rogelio UA, Wendy MB, David MR, Sidika EK. Whey protein supplementation reduces glycemia in patients with type 2 diabetes: a randomized controlled trial. BMJ Open Diabetes Research & Care. 2017;5(1):e000420. doi:10.1136/bmjdrc-2017-000420
Efectos Principales
Whey protein increased insulin secretion levels (1 pmol/L, p<0.05).
Whey protein stimulated GLP-1 secretion (1 pmol/L, p<0.05).
Whey protein suppressed ghrelin levels (-1 pmol/L, p<0.05).
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Whey protein and BMI, GLP-1, GLP-1 secretion stimulated by whey protein, and 4 more.
This study contributes evidence to
Primary intervention
Whey protein
Primary outcomes
- BMI
- GLP-1
- GLP-1 secretion stimulated by whey protein
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
1
Related topics
7
Evidence pairs
376
Related studies
Why it is useful
- Contributes to 7 evidence relationships
- Includes primary outcome data
- Linked to 1 direct semantic evidence topic
Topic contributions
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
Weight Loss
matched_outcome
Core evidence
Study findings
The primary outcomes reported in this study.
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
GLP-1 secretion stimulated by whey protein
Whey protein → GLP-1 secretion stimulated by whey protein
Whey protein → GLP-1 secretion stimulated by whey protein
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Insulin secretion levels after Roux-en-Y gastric bypass surgery
Whey protein → Insulin secretion levels after Roux-en-Y gastric bypass surgery
Whey protein → Insulin secretion levels after Roux-en-Y gastric bypass surgery
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Second-phase insulin response during intravenous glucose tolerance test
Whey protein → Second-phase insulin response during intravenous glucose tolerance test
Whey protein → Second-phase insulin response during intravenous glucose tolerance test
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
La Evidencia Sugiere
- Whey protein significantly increased insulin and GLP-1 secretion.
- Lower BMI and triglycerides predicted decreased glucose levels on whey protein.
- No significant difference in glucose response between whey protein and placebo.
A quién se aplica
- Adults diagnosed with type 2 diabetes.
- Individuals seeking dietary interventions for glycemic control.
Tener en Cuenta
- The findings may not apply to all populations with diabetes.
- Long-term effects of whey protein supplementation were not assessed.
- Individual responses to whey protein may vary based on baseline metabolic characteristics.
Entre Líneas
- The study's sample size may limit the generalizability of the findings.
- Effects of whey protein on glucose response varied based on individual baseline characteristics.
- No significant difference was found between whey protein and placebo on glucose response (p=0.097).
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Whey protein and Body Mass Index, Whey protein and Ghrelin.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Whey protein → Body Mass Index
Diet and Nutrition
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Whey protein → Ghrelin
Diet and Nutrition
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Incluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
Body Mass Index Evidence Hub
All studies measuring Body Mass Index
Measures Body Mass Index as a key outcome.
Ghrelin Evidence Hub
All studies measuring Ghrelin
Measures Ghrelin as a key outcome.
Whey protein Evidence Hub
All studies on Whey protein
Contributes to Whey protein evidence base.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Whey protein and BMI
1 results
All studies on Whey protein and Ghrelin
1 results
All studies on Whey protein
1 results
All studies measuring BMI
1 results
All studies measuring Ghrelin
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Whey protein improve glp-1 secretion stimulated by whey protein?
Whey protein appears to improve glp-1 secretion stimulated by whey protein.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
GLP-1 secretion stimulated by whey protein
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Whey protein improve ghrelin?
Whey protein appears to improve ghrelin.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Ghrelin
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Whey protein improve insulin secretion levels after roux-en-y gastric bypass surgery?
Whey protein appears to improve insulin secretion levels after roux-en-y gastric bypass surgery.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Insulin secretion levels after Roux-en-Y gastric bypass surgery
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Whey protein affect BMI?
Current evidence does not show a clear effect of Whey protein on BMI.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
BMI
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Next steps
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