Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Zinc supplementation shows little effect on glycemic control in Type 2 diabetes
Última actualización 10 de septiembre de 2026
Key finding
There were no significant differences before and after the intervention in the FBG between the two groups.
This study investigated the effects of zinc sulfate supplementation on glycemic control in patients with type 2 diabetes, finding no significant differences in key outcomes.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the effects of zinc sulfate supplementation on glycemic control in patients with type 2 diabetes, finding no significant differences in key outcomes.
Clinical relevance
Understanding the effectiveness of zinc supplementation in managing diabetes is crucial for developing comprehensive treatment plans. This study's findings suggest that zinc may not be a beneficial addition to diabetes management strategies, highlighting the need for further research into alternative interventions.
Keep in mind
Limited sample size may affect the generalizability of results. Short duration of the study may not capture long-term effects. Lack of significant findings raises questions about the intervention's efficacy.
Published in
Referencia de la Revista
Publication details and source links for this paper.
Mehrab S, Sara JN, Fatemeh BI, et al. Effects of Zinc Supplementation on Glycemic Control in Patients with Type 2 Diabetes: A Randomized Controlled Trial. Health Science Reports. 2025;8(1):e70375. doi:10.1002/hsr2.70375
Efectos Principales
No significant differences in fasting blood glucose between intervention and control groups.
No significant changes in glycated hemoglobin levels after zinc supplementation.
Zinc levels did not differ significantly between the two groups.
Body weight increased in the intervention group but not significantly compared to the control.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Zinc supplementation and Body weight, Diastolic blood pressure, Fasting Blood Glucose (FBG), and 4 more.
This study contributes evidence to
Primary intervention
Zinc supplementation
Primary outcomes
- Body weight
- Diastolic blood pressure
- Fasting Blood Glucose (FBG)
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
7
Evidence pairs
7
Relationships
4
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 72
4
Related topics
7
Evidence pairs
1263
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 7 evidence relationships
- Includes primary outcome data
- Linked to 4 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
Blood Pressure
matched_outcome
Evidencia relacionada
Tema de evidencia
Weight Loss
Guardar evidencia
Core evidence
Study findings
The primary outcomes reported in this study.
Diastolic blood pressure
Zinc supplementation → Diastolic blood pressure
Zinc supplementation → Diastolic blood pressure
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerFasting Blood Glucose (FBG)
Zinc supplementation → Fasting Blood Glucose (FBG)
Zinc supplementation → Fasting Blood Glucose (FBG)
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Estudios de apoyo: Basado en 2 estudios
Add to Evidence TrackerSystolic blood pressure
Zinc supplementation → Systolic blood pressure
Zinc supplementation → Systolic blood pressure
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerWaist circumference
Zinc supplementation → Waist circumference
Zinc supplementation → Waist circumference
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
La Evidencia Sugiere
- Zinc supplementation did not significantly alter fasting blood glucose levels.
- No significant changes in glycated hemoglobin were observed.
- Body weight increased in the intervention group, but not significantly.
A quién se aplica
- Adults diagnosed with type 2 diabetes.
- Patients seeking alternative treatments for glycemic control.
Tener en Cuenta
- Results may not apply to populations outside the study sample.
- Further research is needed to explore other potential benefits of zinc.
- The study's short duration limits understanding of long-term effects.
Entre Líneas
- Limited sample size may affect the generalizability of results.
- Short duration of the study may not capture long-term effects.
- Lack of significant findings raises questions about the intervention's efficacy.
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Zinc supplementation and HbA1c, Zinc supplementation and Body Weight.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Zinc supplementation → HbA1c
Supplements
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Estudios de apoyo: Basado en 2 estudios
View evidenceSupplements
Zinc supplementation → Body Weight
Supplements
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceSupplements
Zinc supplementation → Blood Pressure
Supplements
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
HbA1c Evidence Hub
All studies measuring HbA1c
2 studies
outcome_hubMeasures HbA1c as a key outcome.
Zinc supplementation Evidence Hub
All studies on Zinc supplementation
2 studies
intervention_hubContributes to Zinc supplementation evidence base.
Blood Pressure Evidence Hub
All studies measuring Blood Pressure
1 studies
outcome_hubMeasures Blood Pressure as a key outcome.
Body Weight Evidence Hub
All studies measuring Body Weight
1 studies
outcome_hubMeasures Body Weight as a key outcome.
Recent Diabetes Research
Latest published studies
recency_collection
Published within the last 2 years.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Zinc supplementation and HbA1c
Intervention: Zinc supplementationOutcome: HbA1c
2 results
All studies on Zinc supplementation and Body weight
Intervention: Zinc supplementationOutcome: Body weight
1 results
All studies on Zinc supplementation
Intervention: Zinc supplementation
2 results
All studies measuring HbA1c
Outcome: HbA1c
2 results
All studies measuring Body weight
Outcome: Body weight
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Zinc supplementation lower HbA1c?
Moderate Evidence
Zinc supplementation may lower HbA1c.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Evidence caveat: The available evidence reports mixed findings.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
- Only one supporting study is available.
Does Zinc supplementation affect body weight?
Emerging Evidence
Current evidence does not show a clear effect of Zinc supplementation on body weight.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Body weight
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Zinc supplementation improve diastolic blood pressure?
Emerging Evidence
Current evidence does not show a clear benefit of Zinc supplementation for diastolic blood pressure.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Diastolic blood pressure
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Zinc supplementation improve fasting blood glucose (FBG)?
Emerging Evidence
Current evidence does not show a clear benefit of Zinc supplementation for fasting blood glucose (FBG).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Fasting Blood Glucose (FBG)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Next steps
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Evidence topics
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