Research Summary
Analyzed using Evidence Intelligence™

Linkage Program Improves Blood Glucose Management in Elderly Diabetes Patients

Key finding

The linkage program group demonstrated significant reductions in the average number of hypoglycemic events (3.81 vs. 4.13, P = 0.015).

A value-based hospital-community-family linkage program improved blood glucose management in elderly patients with type 2 diabetes compared to conventional management.

Evidence strength

Moderate confidence

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Some Concerns bias
Last updated July 8, 2026

Quick read

Study at a glance

The essential study design details in one scan.

Population

Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes

Intervention

Hospital-community-family linkage program, Conventional management

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Primary outcome

Incidence of hypoglycemic events

Comparator

Conventional Management Group

Plain-language summary

What this paper says

A plain-language read of the study's main message and where it applies.

Study focus

A value-based hospital-community-family linkage program improved blood glucose management in elderly patients with type 2 diabetes compared to conventional management.

Clinical relevance

Improving blood glucose management in elderly patients is crucial to prevent complications associated with diabetes. The findings suggest that integrating community and family support into diabetes care can lead to better health outcomes, potentially reducing healthcare costs and improving quality of life for patients.

Keep in mind

The study's effectiveness remains unclear due to limited evidence on some outcomes. Results may not be generalizable beyond the studied population. Sample size and demographic diversity were not specified.

Published in

Journal Reference

Publication details and source links for this paper.

Xiaojing Z, Haiyan D, Fafa Y, Maoying W, Yuan C, Jiong W. Value-Based Hospital-Community-Family Linkage Program Improves Blood Glucose Management in Elderly Patients with Type 2 Diabetes. Frontiers in Medicine. 2025;12:1656364. doi:10.3389/fmed.2025.1656364

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Main Effects

The linkage program group showed a decrease in hypoglycemic events by 0.32 events (P = 0.015).

Fasting plasma glucose improved by 0.53 mmol/L in the linkage program group (P = 0.013).

Anxiety levels decreased by 15.13% in the linkage program group (P = 0.005).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Structured multidisciplinary case management and Anxiety score, Average daily dose of antidiabetic medications required by participants, Fasting Plasma Glucose (FPG), and 1 more.

Primary intervention

Structured multidisciplinary case management

Primary outcomes

  • Anxiety score
  • Average daily dose of antidiabetic medications required by participants
  • Fasting Plasma Glucose (FPG)

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

4
Evidence pairs
4
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

2

Related topics

4

Evidence pairs

152

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 4 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Core evidence

Study findings

The primary outcomes reported in this study.

StrongDecrease

Anxiety score

Structured multidisciplinary case management → Anxiety score

Structured multidisciplinary case management → Anxiety score

Evidence profile

StrongDecreasePatient-Reported
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StrongDecrease

Average daily dose of antidiabetic medications required by participants

Structured multidisciplinary case management → Average daily dose of antidiabetic medications required by participants

Structured multidisciplinary case management → Average daily dose of antidiabetic medications required by participants

Evidence profile

StrongDecreaseGlycemic Control
Unlock full evidence details
StrongDecrease

Fasting Plasma Glucose (FPG)

Structured multidisciplinary case management → Fasting Plasma Glucose (FPG)

Structured multidisciplinary case management → Fasting Plasma Glucose (FPG)

Evidence profile

StrongDecreaseGlycemic Control
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StrongDecrease

Hypoglycemia events

Structured multidisciplinary case management → Hypoglycemia events

Structured multidisciplinary case management → Hypoglycemia events

Evidence profile

StrongDecreaseSafety
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evidence suggest

Evidence Suggest

  • Linkage program reduced hypoglycemic events by 0.32 events.
  • Fasting plasma glucose improved by 0.53 mmol/L.
  • Anxiety levels decreased by 15.13%.
who this applies

Who this applies to

  • Elderly patients aged 65 and older.
  • Individuals diagnosed with type 2 diabetes.
keep in mind

Keep in Mind

  • Findings may not apply to younger populations or those with type 1 diabetes.
  • Further research is needed to confirm long-term benefits.
  • The study's specific population characteristics may limit broader applicability.
between the lines

Between the Lines

  • The study's effectiveness remains unclear due to limited evidence on some outcomes.
  • Results may not be generalizable beyond the studied population.
  • Sample size and demographic diversity were not specified.

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Diabetes Self-Management Education and Support (DSMES) Programs and Fasting Glucose, Diabetes Self-Management Education and Support (DSMES) Programs and Mental Health.

Related evidence relationships

Explore in Evidence Archive

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Diabetes Self-Management Education and Support (DSMES) Programs affect hypoglycemia?

Emerging Evidence

Diabetes Self-Management Education and Support (DSMES) Programs appears to improve Hypoglycemia.

ConsensusScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Hypoglycemia events

    EvidenceScore™ Emerging | EvidenceScore™ 53.0 | strong positive | ConsensusScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Diabetes Self-Management Education and Support (DSMES) Programs improve mental health?

Emerging Evidence

Diabetes Self-Management Education and Support (DSMES) Programs appears to improve Mental Health.

ConsensusScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Anxiety score

    EvidenceScore™ Emerging | EvidenceScore™ 53.0 | strong positive | ConsensusScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Diabetes Self-Management Education and Support (DSMES) Programs improve fasting glucose?

Emerging Evidence

Diabetes Self-Management Education and Support (DSMES) Programs appears to improve Fasting Glucose.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 57.1 | strong positive | ConsensusScore™ Generally Consistent | 1 study

Why this answer: This answer is based on 7 supporting studies and existing graph evidence signals.

Limitations

  • Consistency cannot yet be determined.
  • Population details are unavailable.
7 supporting studiesUpdated: Jul 2026

Does Structured multidisciplinary case management improve average daily dose of antidiabetic medications required by participants?

Emerging Evidence

Structured multidisciplinary case management appears to improve Average daily dose of antidiabetic medications required by participants.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Average daily dose of antidiabetic medications required by participants

    EvidenceScore™ Emerging | EvidenceScore™ 53.0 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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