Evidence Question

Do SGLT2 inhibitors lower Systolic blood pressure?

Related to: Cardiometabolic Risk

Short answer

SGLT2 inhibitors may lower Systolic blood pressure.

How the evidence connects

Each connection shows the published evidence classification for that intervention and outcome relationship.

Intervention

SGLT2 inhibitors

Intervention

Moderate
Positive
Mixed

2 studies · 2 RCTs

Outcome

Systolic blood pressure

Outcome

Why do we say this?

Some supporting studies report the observed direction, while others do not show the same pattern.

Explore the evidence