Research feed

Latest Diabetes Research

Recently published diabetes studies added to Dediabetes, summarized and organized by intervention and outcome.

Sorted by publication date. Some studies may have been added to Dediabetes later.

Last updated: Jul 22, 2026643 studies indexed

July 2026

Published Jul 22, 2026RCTs

Empagliflozin reduces liver fat in diabetes patients

The study investigated the effects of adding Empagliflozin to standard treatment in patients with Type 2 Diabetes, finding significant reductions in hepatic fat mass and BMI.

Interventions
Empagliflozin
Outcomes
Alanine Aminotransferase (ALT)BMIFIB-4 index+3 more
Added to Dediabetes Jul 22, 2026
Published Jul 22, 2026RCTs

Metronidazole may not improve insulin resistance in type 2 diabetes

This study evaluated the impact of metronidazole as an adjunct to scaling and root planing on insulin resistance in type 2 diabetes patients with periodontitis, finding significant changes in HOMA-IR at 6 months.

Interventions
Control Group Usual ActivityScaling and root planing with metronidazoleScaling and root planing without metronidazole
Outcomes
HOMA-IR measured at 3 monthsHomeostasis model assessment of insulin resistance (HOMA-IR) at 6 months
Added to Dediabetes Jul 22, 2026
Published Jul 22, 2026RCTs

Oral insulin may improve liver health in diabetes patients

This study evaluated the safety and potential therapeutic effects of orally delivered insulin in patients with metabolic dysfunction-associated steatohepatitis and type 2 diabetes mellitus, finding significant reductions in liver fat and fibrosis levels.

Interventions
Insulin therapy
Outcomes
Cardiovascular eventsLiver fat contentMean change in Hemoglobin A1c levels after 12 weeks+4 more
Added to Dediabetes Jul 22, 2026
Published Jul 22, 2026RCTs

Vildagliptin and Metformin Improve Glycemic Control in Type 2 Diabetes

This study investigated the effects of Vildagliptin and Metformin on hepatic steatosis in newly diagnosed Type 2 diabetes patients, showing significant improvements in various metabolic parameters.

Interventions
Dipeptidyl peptidase-4 inhibitorsMetformin
Outcomes
BMIBody weightChange in Hepatic Steatosis Index (HSI)+5 more
Added to Dediabetes Jul 22, 2026
Published Jul 22, 2026RCTs

Dapagliflozin improves liver health in metabolic dysfunction-associated steatohepatitis

This study evaluated the efficacy and safety of dapagliflozin in participants with metabolic dysfunction-associated steatohepatitis (MASH), finding significant improvements in liver health outcomes.

Interventions
Dapagliflozin
Outcomes
Fibrosis improvement without worsening of MASHMean difference in non-alcoholic fatty liver disease activity score (NAS)Resolution of Metabolic Dysfunction Associated Steatohepatitis (MASH)
Added to Dediabetes Jul 22, 2026
Published Jul 22, 2026RCTs

Ozone therapy may improve glycemic control in type 2 diabetes patients

This study investigated the impact of ozone therapy on glycated hemoglobin levels in type 2 diabetes patients, finding no significant reduction in HbA1c levels.

Interventions
Non-surgical periodontal treatment
Outcomes
Bleeding on probingClinical attachment levelHbA1c+2 more
Added to Dediabetes Jul 22, 2026
Published Jul 22, 2026RCTs

Pioglitazone may reduce liver fat more in women than men

This study investigated the efficacy of pioglitazone in treating NAFLD patients with abnormal glucose metabolism, revealing significant liver fat content reduction in women compared to men.

Interventions
Pioglitazone
Outcomes
Liver fat content
Added to Dediabetes Jul 22, 2026
Published Jul 22, 2026RCTs

Probiotics and Tetracycline Improve Periodontitis in Diabetics

This study evaluated the effectiveness of probiotics and tetracycline fibers as adjuncts to scaling and root planing in type 2 diabetic patients with periodontitis, finding significant reductions in inflammatory markers and periodontal indices.

Interventions
ProbioticsTetracycline fibers
Outcomes
Gingival Index (GI)Interleukin-1 beta levels changePeriodontal probing depth+1 more
Added to Dediabetes Jul 22, 2026
Published Jul 22, 2026RCTs

Saroglitazar improves liver health and glycemic control in type 2 diabetes

This study compared the effects of Saroglitazar and Pioglitazone on liver health and blood sugar control in patients with Type 2 Diabetes and liver disease, finding significant improvements in certain measures.

Interventions
PioglitazoneSaroglitazar 4 mg
Outcomes
BMIControlled attenuation parameterHbA1c+2 more
Added to Dediabetes Jul 22, 2026
Published Jul 22, 2026RCTs

Combination therapy improves hepatic steatosis in T2DM patients

This study evaluated the combination therapy of Tofogliflozin and Pioglitazone for treating hepatic steatosis in patients with NAFLD and T2DM, showing significant improvements in various metabolic parameters.

Interventions
Dapagliflozin plus linagliptin combination therapyPioglitazoneTofogliflozin
Outcomes
AdiponectinAlanine Aminotransferase (ALT)Change in ketone body levels after combination therapy+4 more
Added to Dediabetes Jul 22, 2026

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