Resumen de Investigación
Analyzed using Evidence Intelligence™

High protein diet improves fat loss and lowers blood pressure in obese women

Última actualización 2 de septiembre de 2026

Key finding

Diastolic blood pressure decreased more on HP (-3.7 mm Hg [95% CI: -6.2, -1.1; p = 0.005])

A high protein weight-reducing diet led to greater fat loss and lower blood pressure compared to a high carbohydrate, high fiber diet in overweight and obese women.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Short-Term (≤3 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

A high protein weight-reducing diet led to greater fat loss and lower blood pressure compared to a high carbohydrate, high fiber diet in overweight and obese women.

Clinical relevance

These findings are significant for clinicians and patients as they highlight the potential benefits of a high protein diet for weight loss and cardiovascular health in overweight and obese women. With obesity being a major risk factor for various health issues, effective dietary strategies are essential for improving health outcomes in this population.

Keep in mind

Study focused only on women, limiting generalizability to men. Sample size and demographic characteristics may affect broader applicability. Effectiveness of diets may vary based on individual adherence and lifestyle factors.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Lisa ATM, Megan TL, Sheila MW, Rachel CB, Jim M. A realistic high protein weight-reducing diet was associated with greater fat loss and lower blood pressure when compared with a high carbohydrate, high fiber diet in high risk overweight and obese women. Nutrition Journal. 2011;10:40-40. doi:10.1186/1475-2891-10-40

Efectos Principales

Moderate-protein diet resulted in a weight loss of -4.5 kg [95% CI: -3.7, -5.4 kg].

Total body fat loss was -4.0 kg [95% CI: -4.6, -3.4 kg] with the moderate-protein diet.

Diastolic blood pressure decreased by -3.7 mm Hg [95% CI: -6.2, -1.1; p = 0.005] with the moderate-protein diet.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to High-fiber diet, Low-protein diet and Body fat mass, Diastolic blood pressure, Waist circumference, and 1 more.

Primary intervention

High-fiber diet

Primary outcomes

  • Body fat mass
  • Diastolic blood pressure
  • Waist circumference

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

8
Evidence pairs
8
Relationships
3
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

3

Related topics

8

Evidence pairs

660

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 8 evidence relationships
  • Includes primary outcome data
  • Linked to 3 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Tema de evidencia

Body Composition

matched_outcome

Evidencia relacionada

Tema de evidencia

Weight Loss

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

Body fat mass

High-fiber diet → Body fat mass

High-fiber diet → Body fat mass

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Diastolic blood pressure

High-fiber diet → Diastolic blood pressure

High-fiber diet → Diastolic blood pressure

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Waist circumference

High-fiber diet → Waist circumference

High-fiber diet → Waist circumference

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Weight loss dependent effect on HbA1c

High-fiber diet → Weight loss dependent effect on HbA1c

High-fiber diet → Weight loss dependent effect on HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Body fat mass

Low-protein diet → Body fat mass

Low-protein diet → Body fat mass

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 2 estudios
Add to Evidence Tracker

Diastolic blood pressure

Low-protein diet → Diastolic blood pressure

Low-protein diet → Diastolic blood pressure

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Waist circumference

Low-protein diet → Waist circumference

Low-protein diet → Waist circumference

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Weight loss dependent effect on HbA1c

Low-protein diet → Weight loss dependent effect on HbA1c

Low-protein diet → Weight loss dependent effect on HbA1c

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Evidence Library

Build your evidence library

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evidence suggest

La Evidencia Sugiere

  • High protein diet led to a weight loss of -4.5 kg compared to -3.3 kg for the high fiber diet.
  • Total body fat loss was significantly greater with the moderate-protein diet (-4.0 kg vs -2.5 kg).
  • Diastolic blood pressure reduction was more significant in the high protein group (-3.7 mm Hg).
who this applies

A quién se aplica

  • Overweight and obese women at high risk for health complications.
  • Individuals seeking effective dietary strategies for weight loss.
keep in mind

Tener en Cuenta

  • Results may not apply to men or younger populations.
  • Dietary adherence and lifestyle factors can influence outcomes.
  • Further research is needed to explore long-term effects and sustainability of diets.
between the lines

Entre Líneas

  • Study focused only on women, limiting generalizability to men.
  • Sample size and demographic characteristics may affect broader applicability.
  • Effectiveness of diets may vary based on individual adherence and lifestyle factors.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Low-protein diet and Body Composition, High-fiber diet and Body Composition.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Low-protein diet improve body fat mass?

Moderate Evidence

Low-protein diet may improve body fat mass.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Body fat mass

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
1 supporting study

Does High-fiber diet improve body fat mass?

Emerging Evidence

High-fiber diet appears to improve body fat mass.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Body fat mass

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does High-fiber diet affect waist circumference?

Emerging Evidence

High-fiber diet appears to affect waist circumference.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Waist circumference

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does High-fiber diet affect weight loss dependent effect on HbA1c?

Emerging Evidence

High-fiber diet appears to affect weight loss dependent effect on HbA1c.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Weight loss dependent effect on HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
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