Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Lemborexant improves sleep in diabetic patients with insomnia.
Última actualización 29 de agosto de 2026
Key finding
sSOL change from baseline (median) at 6mo was -20.71 minutes for LEM5.
Long-term treatment with lemborexant improved sleep onset and maintenance in diabetic patients with insomnia.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
Long-term treatment with lemborexant improved sleep onset and maintenance in diabetic patients with insomnia.
Clinical relevance
Improving sleep quality in diabetic patients is crucial as insomnia can exacerbate diabetes management and overall health. Effective treatments like lemborexant may enhance sleep, potentially leading to better glycemic control and improved quality of life for these patients.
Keep in mind
Sample size and demographic details not specified. Results may not be generalizable to non-diabetic populations. Effectiveness data were reported as unclear for some outcomes.
Published in
Referencia de la Revista
Publication details and source links for this paper.
Margaret M, Kate P, Jane Y, Jocelyn YC. Long-term treatment with lemborexant appears effective in improving sleep onset and sleep maintenance variables in diabetic patients with insomnia. Journal of the Endocrine Society. 2022;6(Suppl 1):A379-A380. doi:10.1210/jendso/bvac150.790
Efectos Principales
LEM5 reduced sleep onset latency by 20.71 minutes at 6 months.
LEM10 reduced sleep onset latency by 30.71 minutes at 6 months.
LEM5 improved sleep efficiency by 13.20% at 6 months.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Lemborexant 10mg, Lemborexant 5mg and Sleep efficiency, Sleep onset delay score, Total sleep time measured in minutes, and 2 more.
This study contributes evidence to
Primary intervention
Lemborexant 10mg
Primary outcomes
- Sleep efficiency
- Sleep onset delay score
- Total sleep time measured in minutes
Primary intervention
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
10
Evidence pairs
10
Relationships
0
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 50
0
Related topics
10
Evidence pairs
0
Related studies
Why it is useful
- Contributes to 10 evidence relationships
- Includes primary outcome data
- Linked to 0 direct semantic evidence topics
Core evidence
Study findings
The primary outcomes reported in this study.
Sleep onset delay score
Lemborexant 10mg → Sleep onset delay score
Lemborexant 10mg → Sleep onset delay score
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerTotal sleep time measured in minutes
Lemborexant 10mg → Total sleep time measured in minutes
Lemborexant 10mg → Total sleep time measured in minutes
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerTreatment-emergent adverse events
Lemborexant 10mg → Treatment-emergent adverse events
Lemborexant 10mg → Treatment-emergent adverse events
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerWake time after sleep onset in minutes
Lemborexant 10mg → Wake time after sleep onset in minutes
Lemborexant 10mg → Wake time after sleep onset in minutes
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerSleep onset delay score
Lemborexant 5mg → Sleep onset delay score
Lemborexant 5mg → Sleep onset delay score
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerTotal sleep time measured in minutes
Lemborexant 5mg → Total sleep time measured in minutes
Lemborexant 5mg → Total sleep time measured in minutes
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerTreatment-emergent adverse events
Lemborexant 5mg → Treatment-emergent adverse events
Lemborexant 5mg → Treatment-emergent adverse events
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerWake time after sleep onset in minutes
Lemborexant 5mg → Wake time after sleep onset in minutes
Lemborexant 5mg → Wake time after sleep onset in minutes
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
La Evidencia Sugiere
- LEM10 showed a 30.71-minute reduction in sleep onset latency.
- LEM5 improved sleep efficiency by 13.20%.
- Both doses of lemborexant reduced wake after sleep onset significantly.
A quién se aplica
- Adults diagnosed with diabetes.
- Patients experiencing insomnia.
Tener en Cuenta
- The study's long-term effects beyond 6 months are unknown.
- Further research is needed to confirm findings in diverse populations.
- Potential side effects of lemborexant were not detailed.
Entre Líneas
- Sample size and demographic details not specified.
- Results may not be generalizable to non-diabetic populations.
- Effectiveness data were reported as unclear for some outcomes.
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Lemborexant 10mg and Sleep Outcomes, Lemborexant 10mg and Sleep onset delay score.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Medications
Lemborexant 10mg → Sleep Outcomes
Medications
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceMedications
Lemborexant 10mg → Sleep onset delay score
Medications
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
Lemborexant 10mg Evidence Hub
All studies on Lemborexant 10mg
1 studies
intervention_hubContributes to Lemborexant 10mg evidence base.
Sleep onset delay score Evidence Hub
All studies measuring Sleep onset delay score
1 studies
outcome_hubMeasures Sleep onset delay score as a key outcome.
Sleep Outcomes Evidence Hub
All studies measuring Sleep Outcomes
1 studies
outcome_hubMeasures Sleep Outcomes as a key outcome.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Lemborexant 10mg and Sleep efficiency
Intervention: Lemborexant 10mgOutcome: Sleep efficiency
1 results
All studies on Lemborexant 10mg and Sleep onset delay score
Intervention: Lemborexant 10mgOutcome: Sleep onset delay score
1 results
All studies on Lemborexant 10mg
Intervention: Lemborexant 10mg
1 results
All studies measuring Sleep efficiency
Outcome: Sleep efficiency
1 results
All studies measuring Sleep onset delay score
Outcome: Sleep onset delay score
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Lemborexant 10mg improve sleep efficiency?
Emerging Evidence
Lemborexant 10mg appears to improve Sleep efficiency.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Sleep efficiency
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Lemborexant 10mg improve sleep onset delay score?
Emerging Evidence
Lemborexant 10mg appears to improve Sleep onset delay score.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Sleep onset delay score
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Lemborexant 10mg improve total sleep time measured in minutes?
Emerging Evidence
Lemborexant 10mg appears to improve Total sleep time measured in minutes.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Total sleep time measured in minutes
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Lemborexant 10mg improve wake time after sleep onset in minutes?
Emerging Evidence
Lemborexant 10mg appears to improve Wake time after sleep onset in minutes.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Wake time after sleep onset in minutes
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Next steps
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