Resumen de Investigación
Lifestyle changes may improve diabetes remission rates
Moderate confidence
Low bias
Última actualización 15 de junio de 2026Conclusión Clave:
This study evaluated the effects of a one-year lifestyle intervention on type 2 diabetes patients who achieved remission, finding significant improvements in various metabolic parameters.
Estudio de un Vistazo
Participantes
Intervención
One-year lifestyle intervention program
Resultados
Oral Glucose Tolerance Test (OGTT) clearance, Weight change, Body Mass Index (BMI) change, HbA1c change, Fasting Insulin change, Fasting blood sugar (FBS), Post-Prandial Blood Sugar change, HOMA-IR change, HOMA-β change, Diabetic ketoacidosis incidence, Diabetic retinopathy incidence, Diabetic nephropathy incidence, Diabetic neuropathy incidence, Diabetic microvascular complication multimorbidity, Urinary albumin-to-creatinine ratio change, Waist-to-hip ratio change
Financiamiento
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Efectos Principales
52% of participants cleared the OGTT.
Weight decreased by an average of 12.9 kg.
HbA1c levels decreased by 17.1 mmol/mol.
Resumen de Evidencia
| Intervention | Outcome | Measured Change | Study Effect |
|---|---|---|---|
 Complex lifestyle intervention (Behavioral & Lifestyle) |  Body Mass Index (BMI) change (Weight & Anthropometrics) | Decrease | Strong |
Complex lifestyle intervention (Behavioral & Lifestyle) |  Diabetic ketoacidosis (Safety) | No Change | Unclear |
Complex lifestyle intervention (Behavioral & Lifestyle) |  Diabetic microvascular complication multimorbidity (Clinical Outcomes) | No Change | Unclear |
Complex lifestyle intervention (Behavioral & Lifestyle) | Diabetic nephropathy incidence (Clinical Outcomes) | No Change | Unclear |
Complex lifestyle intervention (Behavioral & Lifestyle) | Diabetic neuropathy incidence (Clinical Outcomes) | No Change | Unclear |
Complex lifestyle intervention (Behavioral & Lifestyle) | Diabetic retinopathy incidence (Clinical Outcomes) | No Change | Unclear |
Complex lifestyle intervention (Behavioral & Lifestyle) |  Fasting blood sugar (FBS) (Glycemic Control) | Decrease | Strong |
Complex lifestyle intervention (Behavioral & Lifestyle) |  Fasting insulin levels (Metabolic Health) | Decrease | Strong |
Complex lifestyle intervention (Behavioral & Lifestyle) | Glucose iAUC (OGTT) (Glycemic Control) | Increase | Strong |
Complex lifestyle intervention (Behavioral & Lifestyle) | HbA1c (Glycemic Control) | Decrease | Strong |
Complex lifestyle intervention (Behavioral & Lifestyle) | Homeostatic model assessment for insulin resistance (HOMA-IR) change (Clinical Outcomes) | Decrease | Strong |
Complex lifestyle intervention (Behavioral & Lifestyle) | Postprandial blood glucose (Glycemic Control) | Decrease | Strong |
Complex lifestyle intervention (Behavioral & Lifestyle) | Urinary albumin-to-creatinine ratio (Clinical Outcomes) | Decrease | Strong |
Complex lifestyle intervention (Behavioral & Lifestyle) | Waist-to-hip ratio (Weight & Anthropometrics) | Decrease | Strong |
Complex lifestyle intervention (Behavioral & Lifestyle) | Weight change (Weight & Anthropometrics) | Decrease | Strong |
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La Evidencia Sugiere
- 52% of participants cleared the OGTT.
- Weight decreased by an average of 12.9 kg.
- HbA1c levels decreased by 17.1 mmol/mol.
Tener en Cuenta
- Single-arm study design limits comparison to control groups.
- Results may not be generalizable to all type 2 diabetes patients.
- Potential for unmeasured confounders affecting outcomes.
Entre Líneas
- Single-arm study design limits comparison to control groups.
- Results may not be generalizable to all type 2 diabetes patients.
- Potential for unmeasured confounders affecting outcomes.
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Referencia de la Revista
Pramod T, Nidhi K, Diptika T, et al. Achieving diabetes remission through a structured lifestyle modification program: A quasi-experimental study. PLOS ONE. 2024. doi:10.1371/journal.pone.0302777
Connected Evidence
Discover how this study fits into the broader diabetes evidence landscape.
This study contributes to evidence on Lifestyle Programs and Body Weight, Lifestyle Programs and Glycemic Control.
Relaciones de evidencia relacionadas
Explore in Evidence ArchiveThis study contributes to the evidence on the following intervention–outcome relationships.
Incluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
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outcome_hubMeasures Body Weight as a key outcome.
Glycemic Control Evidence Hub
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outcome_hubMeasures Glycemic Control as a key outcome.
Lifestyle Programs Evidence Hub
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intervention_hubContributes to Lifestyle Programs evidence base.
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Preguntas que esta evidencia ayuda a responder
Key clinical and research questions this study contributes to.
Does complex lifestyle intervention improve Body Mass Index (BMI) change?
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