Última actualización 15 de agosto de 2026
Key finding
FLI significantly decreased from 62.0 at baseline to 53.0 at follow-up.
This study investigated the effects of Low-Volume High-Intensity Interval Training on liver and kidney function in patients with Type 2 Diabetes, finding significant improvements in several health markers.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Extended (5–20+ y)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the effects of Low-Volume High-Intensity Interval Training on liver and kidney function in patients with Type 2 Diabetes, finding significant improvements in several health markers.
These findings highlight the potential of Low-Volume High-Intensity Interval Training as an effective intervention for improving metabolic health in patients with Type 2 Diabetes. By reducing liver fat and enhancing kidney function, this exercise regimen may help mitigate complications associated with diabetes, ultimately improving patient outcomes.
Sample size not specified, limiting generalizability Short duration of intervention may not reflect long-term effects Lack of diversity in participant characteristics could affect applicability
Published in
Publication details and source links for this paper.
Rasoul R, Saeid K, Abbas AG, Maryam HGK, Khadijeh T. The Effect of Low-Volume High-Intensity Interval Training on Fatty Liver Index and Glomerular Filtration Rate in Patients with Type 2 Diabetes Mellitus. Current Diabetes Reviews. 2024;21(10):E15733998320832. doi:10.2174/0115733998320832240805113238
Fatty Liver Index decreased by 9 units (P < 0.001)
Estimated Glomerular Filtration Rate increased by 2.6 mL/min/1.73m² (P < 0.001)
Fasting Blood Sugar decreased by 8 mg/dL (P < 0.001)
Alanine Aminotransferase decreased by 6 IU/L (P < 0.001)
Gamma-Glutamyl Transferase decreased by 3 IU/L (P < 0.001)
Evidence network
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This study contributes evidence to High-intensity interval exercise and Alanine Aminotransferase (ALT), Change in liver enzymes (GGT), Estimated glomerular filtration rate, and 2 more.
This study contributes evidence to
Primary intervention
High-intensity interval exercise
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
5
Evidence pairs
886
Related studies
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
matched_outcome
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Core evidence
The primary outcomes reported in this study.
High-intensity interval exercise → Alanine Aminotransferase (ALT)
High-intensity interval exercise → Alanine Aminotransferase (ALT)
High-intensity interval exercise → Change in liver enzymes (GGT)
High-intensity interval exercise → Change in liver enzymes (GGT)
High-intensity interval exercise → Estimated glomerular filtration rate
High-intensity interval exercise → Estimated glomerular filtration rate
High-intensity interval exercise → Fasting blood sugar (FBS)
High-intensity interval exercise → Fasting blood sugar (FBS)
High-intensity interval exercise → Fatty liver index
High-intensity interval exercise → Fatty liver index
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on High-intensity interval exercise and Adipokine and Angiogenic Markers, High-intensity interval exercise and Kidney Function.
This study contributes to the evidence on the following intervention-outcome relationships.
Physical Activity
Physical Activity
Curated evidence collections and hubs this study is part of.
All studies measuring Adipokine and Angiogenic Markers
Measures Adipokine and Angiogenic Markers as a key outcome.
All studies on High-intensity interval exercise
Contributes to High-intensity interval exercise evidence base.
All studies measuring Kidney Function
Measures Kidney Function as a key outcome.
Latest published studies
Published within the last 2 years.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
High-intensity interval exercise appears to improve alanine aminotransferase (ALT).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Alanine Aminotransferase (ALT)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
High-intensity interval exercise appears to improve change in liver enzymes (GGT).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Change in liver enzymes (GGT)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
High-intensity interval exercise appears to improve estimated glomerular filtration rate.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Estimated glomerular filtration rate
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
High-intensity interval exercise appears to improve fasting blood sugar (FBS).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Fasting blood sugar (FBS)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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