Resumen de Investigación
Mediterranean diet may improve insulin response in type 2 diabetes
Moderate confidence
Low bias
Última actualización 12 de junio de 2026Conclusión Clave:
This study evaluated the postprandial effects of three diets in patients with type 2 diabetes, finding significant differences in insulin and glucose responses.
Estudio de un Vistazo
Participantes
Intervención
Low-carbohydrate diet, Low-fat diet, Mediterranean-style diet
Resultados
Insulin response, Postprandial glucose, Glucose excursions
Financiamiento
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Efectos Principales
The low-carbohydrate diet induced lower insulin excursions compared to the low-fat diet (-0.87 pmol/l, p<0.0005).
The low-carbohydrate diet induced lower glucose excursions compared to the low-fat diet (-0.87 mmol/l, p<0.0005).
The insulin-response following the Mediterranean-style diet was more pronounced than during the low-fat diet lunch (4.35 pmol/l, p=0.001).
Resumen de Evidencia
| Intervention | Outcome | Measured Change | Study Effect |
|---|---|---|---|
 Low-carbohydrate diet (Diet and Nutrition) |  Postprandial blood glucose (Glycemic Control) | Decrease | Strong |
Low-carbohydrate diet (Diet and Nutrition) | Postprandial insulin AUC (Glycemic Control) | Decrease | Strong |
Low-fat diet (Diet and Nutrition) | Postprandial blood glucose (Glycemic Control) | No Change | Unclear |
Low-fat diet (Diet and Nutrition) | Postprandial insulin AUC (Glycemic Control) | Decrease | Strong |
Mediterranean diet (Diet and Nutrition) | Postprandial blood glucose (Glycemic Control) | No Change | Unclear |
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La Evidencia Sugiere
- The low-carbohydrate diet induced lower insulin excursions compared to the low-fat diet (-0.87 pmol/l, p<0.0005).
- The low-carbohydrate diet induced lower glucose excursions compared to the low-fat diet (-0.87 mmol/l, p<0.0005).
- The insulin-response following the Mediterranean-style diet was more pronounced than during the low-fat diet lunch (4.35 pmol/l, p=0.001).
Tener en Cuenta
- Unclear effectiveness of the Mediterranean-style diet compared to the low-fat diet.
- Limited generalizability due to specific population studied.
- Potential unmeasured confounders affecting outcomes.
Entre Líneas
- Unclear effectiveness of the Mediterranean-style diet compared to the low-fat diet.
- Limited generalizability due to specific population studied.
- Potential unmeasured confounders affecting outcomes.
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Referencia de la Revista
Hanna F, Christine J, Bekim B, et al. Postprandial Effects of Low-Fat, Low-Carbohydrate, and Mediterranean Diets in Type 2 Diabetes. PLoS ONE. 2013. doi:10.1371/journal.pone.0079324
Connected Evidence
Discover how this study fits into the broader diabetes evidence landscape.
This study contributes to evidence on Low-Carbohydrate Diets and Glycemic Control, Low-Carbohydrate Diets and Insulin Resistance.
Relaciones de evidencia relacionadas
Explore in Evidence ArchiveThis study contributes to the evidence on the following intervention–outcome relationships.
Incluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
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Preguntas que esta evidencia ayuda a responder
Key clinical and research questions this study contributes to.
Does low-carbohydrate diet improve Postprandial blood glucose?
Based on connected evidence for Low-carbohydrate diet and Postprandial blood glucose.
Does low-carbohydrate diet affect Postprandial insulin AUC in people with diabetes?
Exploring evidence on Low-carbohydrate diet and Postprandial insulin AUC outcomes.
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