Resumen de Investigación
Analyzed using Evidence Intelligence™

Muscle-building interventions improve glycemic control in elderly with T2 diabetes

Última actualización 21 de agosto de 2026

Key finding

HbA1c significantly decreased after resistance training.

This study evaluated the effects of resistance training with and without whey protein on glycemic parameters in elderly patients with type 2 diabetes and sarcopenic obesity, finding significant improvements in several outcomes with resistance training.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

Guarda investigacion, organiza estudios y vuelve a encontrar evidencia importante rapidamente.

Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the effects of resistance training with and without whey protein on glycemic parameters in elderly patients with type 2 diabetes and sarcopenic obesity, finding significant improvements in several outcomes with resistance training.

Clinical relevance

These findings highlight the importance of resistance training as a viable intervention for managing glycemic control in elderly patients with type 2 diabetes and sarcopenic obesity. Given the rising prevalence of diabetes and obesity in older adults, effective interventions are crucial for improving health outcomes and quality of life.

Keep in mind

Limited sample size may affect generalizability. No long-term follow-up to assess sustained effects. Potential confounding factors not controlled for.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Tingting H, Xinyue L, Hongxia L, et al. Effect of muscle-building interventions on glycemic parameters in elderly patients with type 2 diabetes and sarcopenic obesity. Nutrition & Metabolism. 2025;22:98. doi:10.1186/s12986-025-00993-2

Efectos Principales

HbA1c decreased by 0.5% (p=0.01) after resistance training.

2-hour plasma glucose decreased by 1.2 mmol/L (p=0.01) after resistance training.

Insulin resistance (HOMA-IR) decreased by 1.5 units (p=0.01) after resistance training.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Resistance training and 2-hour plasma glucose, Gutt index, HbA1c, and 1 more.

Primary intervention

Resistance training

Primary outcomes

  • 2-hour plasma glucose
  • Gutt index
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

4
Evidence pairs
4
Relationships
5
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 72

5

Related topics

4

Evidence pairs

1701

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 4 evidence relationships
  • Includes primary outcome data
  • Linked to 5 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Agrega evidencia relacionada a tu Evidence Tracker

Guarda estudios y paginas de evidencia, organiza tu Evidence Tracker y manten en un solo lugar la investigacion que te importa.

Evidencia principal

Tema de evidencia

Insulin Resistance

matched_intervention_and_outcome

Evidencia relacionada

Tema de evidencia

Prediabetes

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

2-hour plasma glucose

Resistance training → 2-hour plasma glucose

Resistance training → 2-hour plasma glucose

Evidence Intelligence™
EvidenceScore™
74
Moderate
ImpactScore™
63
Slightly Positive
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 4 estudios
Add to Evidence Tracker

Gutt index

Resistance training → Gutt index

Resistance training → Gutt index

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

HbA1c

Resistance training → HbA1c

Resistance training → HbA1c

Evidence Intelligence™
EvidenceScore™
82
Strong
ImpactScore™
92
Very Positive
ConsistencyScore™
80
consistent
Estudios de apoyo: Basado en 6 estudios
Add to Evidence Tracker

Insulin resistance

Resistance training → Insulin resistance

Resistance training → Insulin resistance

Evidence Intelligence™
EvidenceScore™
79
Strong
ImpactScore™
85
Very Positive
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 3 estudios
Add to Evidence Tracker

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

evidence suggest

La Evidencia Sugiere

  • Resistance training led to a significant decrease in HbA1c by 0.5%.
  • 2-hour plasma glucose decreased significantly by 1.2 mmol/L.
  • Insulin resistance improved with a decrease of 1.5 units.
who this applies

A quién se aplica

  • Elderly patients aged 65 and older.
  • Individuals diagnosed with type 2 diabetes.
  • Patients exhibiting signs of sarcopenic obesity.
keep in mind

Tener en Cuenta

  • Results may not apply to younger populations.
  • Findings specific to resistance training and may not extend to other forms of exercise.
  • Whey protein supplementation did not show additional benefits.
between the lines

Entre Líneas

  • Limited sample size may affect generalizability.
  • No long-term follow-up to assess sustained effects.
  • Potential confounding factors not controlled for.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Resistance training and HbA1c, Resistance training and Insulin Resistance.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Resistance training lower HbA1c?

Strong Evidence

Resistance training appears to lower HbA1c.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Strong | EvidenceScore™ 82.4 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Resistance training improve insulin resistance?

Strong Evidence

Resistance training appears to improve insulin resistance.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Insulin resistance

    EvidenceScore™ Strong | EvidenceScore™ 78.5 | strong positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Resistance training improve 2-hour plasma glucose?

Moderate Evidence

Resistance training may improve 2-hour plasma glucose.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    2-hour plasma glucose

    EvidenceScore™ Moderate | EvidenceScore™ 74.5 | weak positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Only one supporting study is available.
1 supporting study

Does Resistance training improve gutt index?

Emerging Evidence

Resistance training appears to improve gutt index.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Gutt index

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
1 supporting study
Learn how Evidence Intelligence™ works

Next steps

Continue your research

Choose a next path through related evidence topics, Evidence Explorer views, and research summaries.

Sin anuncios. Sin rastreo.

Centrada en la evidencia, no en la publicidad.

Segura y privada

Tus datos siempre están protegidos.

Siempre al día

Se agregan nuevos estudios todos los días.