Resumen de Investigación
Analyzed using Evidence Intelligence™

Normal weight obesity linked to higher diabetes risk in South India

Última actualización 27 de agosto de 2026

Key finding

The proportion with NWO was 32% (n = 364; 95% CI: 29.1 to 34.5%)

This study assessed the prevalence of Normal Weight Obesity (NWO) and its cardiometabolic profile in a high diabetes risk population in South India, finding a 32% prevalence of NWO.

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Extended (5–20+ y)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study assessed the prevalence of Normal Weight Obesity (NWO) and its cardiometabolic profile in a high diabetes risk population in South India, finding a 32% prevalence of NWO.

Clinical relevance

Understanding the prevalence of Normal Weight Obesity in populations at high risk for diabetes is crucial for early intervention and management strategies. The high rates of dyslipidemia and elevated blood pressure among those with NWO suggest that even individuals with normal weight can have significant cardiometabolic risks, necessitating targeted health strategies.

Keep in mind

Single-arm study limits comparison with control groups. Findings may not be generalizable beyond the South Indian population. Lack of significant differences in diabetes incidence may limit conclusions.

Published in

Referencia de la Revista

Publication details and source links for this paper.

Nitin K, Mojtaba L, Thirunavukkarasu S, et al. Prevalence of Normal Weight Obesity and Its Cardiometabolic Profile in a High Diabetes Risk Population in South India. PLOS ONE. 2020;15(8):e0237974. doi:10.1371/journal.pone.0237974

Efectos Principales

32% prevalence of Normal Weight Obesity (NWO) in the population studied.

Mean systolic blood pressure among those with NWO was 129 ± 20 mmHg.

Dyslipidemia was present in 89.2% of individuals with NWO.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Peer-support lifestyle program and Adrenocorticotropic hormone (ACTH) levels following RYGB, Diastolic blood pressure, Dyslipidemia prevalence, and 4 more.

Primary intervention

Peer-support lifestyle program

Primary outcomes

  • Adrenocorticotropic hormone (ACTH) levels following RYGB
  • Diastolic blood pressure
  • Dyslipidemia prevalence

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

7
Evidence pairs
7
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 65

2

Related topics

7

Evidence pairs

367

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 7 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

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Evidencia principal

Relación de evidencia

Diabetes Self-Management Education and Support (DSMES) Programs and Blood Pressure

Evidencia relacionada

Relación de evidencia

Diabetes Self-Management Education and Support (DSMES) Programs and Adipokine and Angiogenic Markers

Guardar evidencia

Relación de evidencia

Diabetes Self-Management Education and Support (DSMES) Programs and Diabetes Incidence and Prevention

Guardar evidencia

Core evidence

Study findings

The primary outcomes reported in this study.

Adrenocorticotropic hormone (ACTH) levels following RYGB

Peer-support lifestyle program → Adrenocorticotropic hormone (ACTH) levels following RYGB

Peer-support lifestyle program → Adrenocorticotropic hormone (ACTH) levels following RYGB

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Diastolic blood pressure

Peer-support lifestyle program → Diastolic blood pressure

Peer-support lifestyle program → Diastolic blood pressure

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Dyslipidemia prevalence

Peer-support lifestyle program → Dyslipidemia prevalence

Peer-support lifestyle program → Dyslipidemia prevalence

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

LDL cholesterol

Peer-support lifestyle program → LDL cholesterol

Peer-support lifestyle program → LDL cholesterol

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Systolic blood pressure

Peer-support lifestyle program → Systolic blood pressure

Peer-support lifestyle program → Systolic blood pressure

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Triglycerides

Peer-support lifestyle program → Triglycerides

Peer-support lifestyle program → Triglycerides

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence Tracker

Type 2 diabetes incidence

Peer-support lifestyle program → Type 2 diabetes incidence

Peer-support lifestyle program → Type 2 diabetes incidence

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
53
Neutral
ConsistencyScore™
35
mixed
Estudios de apoyo: Basado en 2 estudios
Add to Evidence Tracker

Evidence Library

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evidence suggest

La Evidencia Sugiere

  • 32% of participants had Normal Weight Obesity.
  • Mean LDL cholesterol was 158.6 mg/dl in those with NWO.
  • Dyslipidemia was present in 89.2% of individuals with NWO.
who this applies

A quién se aplica

  • Adults at high risk for diabetes in South India.
  • Individuals with normal weight but potential metabolic risks.
keep in mind

Tener en Cuenta

  • The study's single-arm design limits causal inferences.
  • Results may not apply to populations outside South India.
  • Further research is needed to explore long-term health outcomes.
between the lines

Entre Líneas

  • Single-arm study limits comparison with control groups.
  • Findings may not be generalizable beyond the South Indian population.
  • Lack of significant differences in diabetes incidence may limit conclusions.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Diabetes Self-Management Education and Support (DSMES) Programs and Diabetes Incidence and Prevention, Diabetes Self-Management Education and Support (DSMES) Programs and Adrenocorticotropic hormone (ACTH) levels following RYGB.

Relaciones de evidencia relacionadas

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Incluido en estas colecciones de evidencia

Curated evidence collections and hubs this study is part of.

Explora más en Evidence Explorer

Jump to pre-filtered views in Evidence Explorer.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Diabetes Self-Management Education and Support (DSMES) Programs improve blood pressure?

Strong Evidence

Diabetes Self-Management Education and Support (DSMES) Programs may improve Blood Pressure.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Diastolic blood pressure

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

  2. 2

    Systolic blood pressure

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Population details are unavailable.
11 supporting studiesUpdated: Aug 2026

Does Diabetes Self-Management Education and Support (DSMES) Programs improve adipokine and angiogenic markers?

Strong Evidence

Diabetes Self-Management Education and Support (DSMES) Programs may improve Adipokine and Angiogenic Markers.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    LDL cholesterol

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

  2. 2

    Triglycerides

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 11 supporting studies with generally consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
11 supporting studiesUpdated: Aug 2026

Does Diabetes Self-Management Education and Support (DSMES) Programs improve diabetes incidence and prevention?

Strong Evidence

Diabetes Self-Management Education and Support (DSMES) Programs may improve Diabetes Incidence and Prevention.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Type 2 diabetes incidence

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | neutral | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is based on 4 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
4 supporting studiesUpdated: Aug 2026

Does Peer-support lifestyle program improve adrenocorticotropic hormone (acth) levels following rygb?

Emerging Evidence

Peer-support lifestyle program appears to improve Adrenocorticotropic hormone (ACTH) levels following RYGB.

ConsistencyScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Adrenocorticotropic hormone (ACTH) levels following RYGB

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Aug 2026
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