Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Prebiotics may improve insulin resistance in elderly adults
Última actualización 2 de septiembre de 2026
Key finding
There was a significant difference over time in blood glucose (p = 0.0301) in ELD adults who consumed MSPrebiotic compared to placebo.
Dietary supplementation with MSPrebiotic digestion resistant starch improved insulin resistance in elderly adults.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
Dietary supplementation with MSPrebiotic digestion resistant starch improved insulin resistance in elderly adults.
Clinical relevance
Improving insulin resistance is crucial for preventing type 2 diabetes and other metabolic disorders, especially in the elderly who are at higher risk. These findings suggest that dietary interventions, such as prebiotic supplementation, could be a practical approach to enhance metabolic health in this population.
Keep in mind
The study's findings may not be generalizable to younger populations. No significant changes were observed in mid-age adults, limiting broader applicability. The sample size and demographic characteristics were not detailed.
Published in
Referencia de la Revista
Publication details and source links for this paper.
Michelle JA, David S, Paramjit ST, et al. Dietary Supplementation with Prebiotics Improves Insulin Resistance in Elderly Adults. Frontiers in Medicine. 2018;4:260. doi:10.3389/fmed.2017.00260
Efectos Principales
Blood glucose levels decreased by 0.5 mmol/L (p = 0.0301) in elderly adults consuming MSPrebiotic.
Insulin levels decreased by 1 µIU/mL (p = 0.009) in elderly adults consuming MSPrebiotic.
Insulin resistance (HOMA-IR) decreased by 0.5 units (p = 0.009) in elderly adults consuming MSPrebiotic.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Resistant starch (HAM-RS2) and Blood glucose, Insulin, Insulin levels in middle-aged adults, and 1 more.
This study contributes evidence to
Primary intervention
Resistant starch (HAM-RS2)
Primary outcomes
- Blood glucose
- Insulin
- Insulin levels in middle-aged adults
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
4
Evidence pairs
4
Relationships
2
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 64
2
Related topics
4
Evidence pairs
886
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 4 evidence relationships
- Includes primary outcome data
- Linked to 2 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
Fasting Blood Glucose
matched_outcome
Evidencia relacionada
Tema de evidencia
Glycemic Control
Guardar evidencia
Core evidence
Study findings
The primary outcomes reported in this study.
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 2 estudios
Add to Evidence TrackerInsulin levels in middle-aged adults
Resistant starch (HAM-RS2) → Insulin levels in middle-aged adults
Resistant starch (HAM-RS2) → Insulin levels in middle-aged adults
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerInsulin resistance
Resistant starch (HAM-RS2) → Insulin resistance
Resistant starch (HAM-RS2) → Insulin resistance
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
La Evidencia Sugiere
- Elderly adults showed significant reductions in blood glucose and insulin levels.
- Insulin resistance improved significantly with MSPrebiotic supplementation.
- No significant effects were observed in mid-age adults.
A quién se aplica
- Elderly adults at risk for insulin resistance or type 2 diabetes.
- Individuals seeking dietary interventions to improve metabolic health.
Tener en Cuenta
- Results may not apply to younger individuals or those with different health conditions.
- Further research is needed to confirm long-term effects and mechanisms.
- The study did not explore the effects of MSPrebiotic on other age groups.
Entre Líneas
- The study's findings may not be generalizable to younger populations.
- No significant changes were observed in mid-age adults, limiting broader applicability.
- The sample size and demographic characteristics were not detailed.
Evidence Library
Build your evidence library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Resistant starch (HAM-RS2) and Insulin Resistance, Resistant starch (HAM-RS2) and Fasting Glucose.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Resistant starch (HAM-RS2) → Insulin Resistance
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- 100
- consistent
Estudios de apoyo: Basado en 2 estudios
View evidenceDiet and Nutrition
Resistant starch (HAM-RS2) → Fasting Glucose
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Estudios de apoyo: Basado en 1 estudio
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
Insulin Resistance Evidence Hub
All studies measuring Insulin Resistance
2 studies
outcome_hubMeasures Insulin Resistance as a key outcome.
Resistant starch (HAM-RS2) Evidence Hub
All studies on Resistant starch (HAM-RS2)
2 studies
intervention_hubContributes to Resistant starch (HAM-RS2) evidence base.
Fasting Glucose Evidence Hub
All studies measuring Fasting Glucose
1 studies
outcome_hubMeasures Fasting Glucose as a key outcome.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Resistant starch (HAM-RS2) and Insulin
Intervention: Resistant starch (HAM-RS2)Outcome: Insulin
2 results
All studies on Resistant starch (HAM-RS2) and Blood glucose
Intervention: Resistant starch (HAM-RS2)Outcome: Blood glucose
1 results
All studies on Resistant starch (HAM-RS2)
Intervention: Resistant starch (HAM-RS2)
2 results
All studies measuring Insulin
Outcome: Insulin
2 results
All studies measuring Blood glucose
Outcome: Blood glucose
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Resistant starch (HAM-RS2) improve insulin?
Moderate Evidence
Resistant starch (HAM-RS2) appears to improve insulin.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Insulin
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Resistant starch (HAM-RS2) improve blood glucose?
Emerging Evidence
Resistant starch (HAM-RS2) appears to improve blood glucose.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Blood glucose
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Resistant starch (HAM-RS2) improve insulin resistance?
Emerging Evidence
Resistant starch (HAM-RS2) appears to improve insulin resistance.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Insulin resistance
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Resistant starch (HAM-RS2) improve insulin levels in middle-aged adults?
Emerging Evidence
Current evidence does not show a clear benefit of Resistant starch (HAM-RS2) for insulin levels in middle-aged adults.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Insulin levels in middle-aged adults
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Next steps
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