Evidence Intelligence™
- EvidenceScore™
- 82
- Strong
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Estudios de apoyo: Basado en 6 estudios
Add to Evidence TrackerResumen de Investigación
Analyzed using Evidence Intelligence™
Time-Restricted Eating Improves Weight Loss in Type 2 Diabetes
Última actualización 18 de julio de 2026
Key finding
Body weight decreased significantly in the TRE group (−3.56% [95% CI, −5.92% to −1.20%]; P = .004).
This study compared Time-Restricted Eating (TRE) and Daily Calorie Restriction (CR) for weight loss in adults with Type 2 Diabetes, finding TRE to be more effective.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study compared Time-Restricted Eating (TRE) and Daily Calorie Restriction (CR) for weight loss in adults with Type 2 Diabetes, finding TRE to be more effective.
Clinical relevance
This study highlights the potential of Time-Restricted Eating as a more effective dietary strategy for weight management in adults with Type 2 Diabetes. Given the challenges of weight loss in this population, identifying effective interventions is crucial for improving health outcomes and managing diabetes.
Keep in mind
Limited sample size may affect generalizability. Short duration of the study may not reflect long-term effects. No assessment of adherence to dietary interventions.
Published in
Referencia de la Revista
Publication details and source links for this paper.
Vasiliki P, Sofia C, Shuhao L, et al. Is Time-Restricted Eating More Effective Than Daily Calorie Restriction for Weight Loss in Adults With Type 2 Diabetes?. JAMA Network Open. 2023;6(10):e2339337. doi:10.1001/jamanetworkopen.2023.39337
Efectos Principales
TRE group demonstrated a significant weight loss of −3.56% (P = .004).
CR group showed a non-significant weight loss of −1.78% (P = .06).
No significant differences in HbA1c changes between TRE (−0.91%) and CR (−0.94%).
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Calorie restriction, Time-Restricted Eating (TRE) and Body weight, HbA1c.
This study contributes evidence to
Primary intervention
Calorie restriction
Primary outcomes
- Body weight
- HbA1c
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
4
Evidence pairs
4
Relationships
3
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
3
Related topics
4
Evidence pairs
1787
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 4 evidence relationships
- Includes primary outcome data
- Linked to 3 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Tema de evidencia
Dietary Patterns
matched_intervention_and_outcome
Evidencia relacionada
Tema de evidencia
HbA1c Reduction
Guardar evidencia
Core evidence
Study findings
The primary outcomes reported in this study.
Evidence Intelligence™
- EvidenceScore™
- 83
- Strong
- ImpactScore™
- 90
- Very Positive
- ConsistencyScore™
- 80
- consistent
Estudios de apoyo: Basado en 5 estudios
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- 83
- Strong
- ImpactScore™
- 80
- Positive
- ConsistencyScore™
- 80
- consistent
Estudios de apoyo: Basado en 5 estudios
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Strong
- Score 79 · Based on 4 studies
- ImpactScore™
- 63
- Slightly Positive
- ConsistencyScore™
- 75
- consistent
Estudios de apoyo: Basado en 4 estudios
Add to Evidence TrackerEvidence Library
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La Evidencia Sugiere
- TRE led to a significant weight reduction of −3.56%.
- CR resulted in a non-significant weight change of −1.78%.
- HbA1c levels remained similar between TRE and CR groups.
A quién se aplica
- Adults aged 18-65 with Type 2 Diabetes.
- Individuals seeking weight loss strategies.
Tener en Cuenta
- Results may not apply to older adults or those with other health conditions.
- Long-term effects of TRE and CR were not evaluated.
- Individual responses to dietary interventions can vary.
Entre Líneas
- Limited sample size may affect generalizability.
- Short duration of the study may not reflect long-term effects.
- No assessment of adherence to dietary interventions.
Evidence Library
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Calorie restriction and HbA1c, Time-Restricted Eating (TRE) and Body Weight.
Relaciones de evidencia relacionadas
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Calorie restriction → HbA1c
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- 83
- Strong
- ImpactScore™
- 90
- Very Positive
- ConsistencyScore™
- 80
- consistent
Estudios de apoyo: Basado en 5 estudios
View evidenceDiet and Nutrition
Time-Restricted Eating (TRE) → Body Weight
Diet and Nutrition
Evidence Intelligence™
- EvidenceScore™
- 83
- Strong
- ImpactScore™
- 80
- Positive
- ConsistencyScore™
- 80
- consistent
Estudios de apoyo: Basado en 5 estudios
View evidenceIncluido en estas colecciones de evidencia
Curated evidence collections and hubs this study is part of.
Body Weight Evidence Hub
All studies measuring Body Weight
5 studies
outcome_hubMeasures Body Weight as a key outcome.
Calorie restriction Evidence Hub
All studies on Calorie restriction
5 studies
intervention_hubContributes to Calorie restriction evidence base.
HbA1c Evidence Hub
All studies measuring HbA1c
5 studies
outcome_hubMeasures HbA1c as a key outcome.
Time-Restricted Eating (TRE) Evidence Hub
All studies on Time-Restricted Eating (TRE)
5 studies
intervention_hubContributes to Time-Restricted Eating (TRE) evidence base.
Explora más en Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Calorie restriction and HbA1c
Intervention: Calorie restrictionOutcome: HbA1c
5 results
All studies on Time-Restricted Eating (TRE) and Body weight
Intervention: Time-Restricted Eating (TRE)Outcome: Body weight
5 results
All studies on Calorie restriction
Intervention: Calorie restriction
5 results
All studies on Time-Restricted Eating (TRE)
Intervention: Time-Restricted Eating (TRE)
5 results
All studies measuring HbA1c
Outcome: HbA1c
5 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Calorie restriction lower HbA1c?
Strong Evidence
Calorie restriction appears to lower HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 83.4 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Time-Restricted Eating (TRE) affect body weight?
Strong Evidence
Time-Restricted Eating (TRE) may affect body weight.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
Body weight
EvidenceScore™ Strong | EvidenceScore™ 82.7 | moderate positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Does Calorie restriction affect body weight?
Strong Evidence
Calorie restriction may affect body weight.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Evidence caveat: The available evidence reports mixed findings.
Ranked evidence signals
- 1
Body weight
EvidenceScore™ Strong | EvidenceScore™ 82.3 | moderate positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
- Only one supporting study is available.
Does Time-Restricted Eating (TRE) lower HbA1c?
Strong Evidence
Time-Restricted Eating (TRE) may lower HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 79.0 | weak positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
Next steps
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Related research
Read related research summaries.
Time-restricted eating may improve adherence in type 2 diabetesTime-Restricted Eating Shows No Effect on Mood or Quality of Life in DiabetesTime-restricted feeding improves blood glucose and weight in type 2 diabetesEarly time-restricted eating may improve glucose profiles in adults with obesityTime-restricted diet aids glucose control in diabetes
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