Última actualización 21 de agosto de 2026
Key finding
At both 8 and 12 weeks, diabetes remission was achieved in 79%.
A very-low-calorie diet led to short-term diabetes remission in obese Thai patients, with significant improvements in metabolic markers.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Short-Term (≤3 mo)
Risk of bias
Some Concerns
Guarda investigacion, organiza estudios y vuelve a encontrar evidencia importante rapidamente.
Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
A very-low-calorie diet led to short-term diabetes remission in obese Thai patients, with significant improvements in metabolic markers.
These findings highlight the potential of dietary interventions in managing obesity-related diabetes, suggesting that a very-low-calorie diet could be a viable option for achieving rapid metabolic improvements and diabetes remission in similar patient populations.
Single-arm study limits generalizability. Short follow-up period may not reflect long-term effects. Lack of control group reduces comparative analysis.
Published in
Publication details and source links for this paper.
Mongkontida U, Pornsawan P, Juntagan A, et al. Very-low-calorie diet induces short-term diabetes remission in obese Thai patients. Food Science & Nutrition. 2019;7(3):1113-1122. doi:10.1002/fsn3.956
79% of participants achieved diabetes remission at 8 and 12 weeks.
Fasting plasma glucose decreased by 3.8 mmol/L (from 10.1 to 6.3 mmol/L).
Body weight decreased by 9.5 kg (from 71.9 to 62.4 kg).
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Very-low-calorie ketogenic diet and Beta-cell function, Diabetes remission, Fasting Plasma Glucose (FPG), and 5 more.
This study contributes evidence to
Primary intervention
Very-low-calorie ketogenic diet
Primary outcomes
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
4
Related topics
8
Evidence pairs
1250
Related studies
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Guarda estudios y paginas de evidencia, organiza tu Evidence Tracker y manten en un solo lugar la investigacion que te importa.
Evidencia principal
Relación de evidencia
Evidencia relacionada
Relación de evidencia
Guardar evidencia
Relación de evidencia
Guardar evidencia
Core evidence
The primary outcomes reported in this study.
Very-low-calorie ketogenic diet → Beta-cell function
Very-low-calorie ketogenic diet → Beta-cell function
Very-low-calorie ketogenic diet → Diabetes remission
Very-low-calorie ketogenic diet → Diabetes remission
Very-low-calorie ketogenic diet → Fasting Plasma Glucose (FPG)
Very-low-calorie ketogenic diet → Fasting Plasma Glucose (FPG)
Very-low-calorie ketogenic diet → Insulin resistance
Very-low-calorie ketogenic diet → Insulin resistance
Very-low-calorie ketogenic diet → Quality of life
Very-low-calorie ketogenic diet → Quality of life
Very-low-calorie ketogenic diet → type 2 diabetes mellitus
Very-low-calorie ketogenic diet → type 2 diabetes mellitus
Very-low-calorie ketogenic diet → Weight loss dependent effect on HbA1c
Very-low-calorie ketogenic diet → Weight loss dependent effect on HbA1c
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Ketogenic Diets and Fasting Glucose, Ketogenic Diets and HbA1c.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies measuring Fasting Glucose
Measures Fasting Glucose as a key outcome.
All studies measuring HbA1c
Measures HbA1c as a key outcome.
All studies on Ketogenic Diets
Contributes to Ketogenic Diets evidence base.
All studies measuring Quality of Life Outcomes
Measures Quality of Life Outcomes as a key outcome.
Jump to pre-filtered views in Evidence Explorer.
3 results
3 results
3 results
3 results
3 results
Generated from the study's connected evidence using Evidence Intelligence™.
Ketogenic Diets may improve Insulin Resistance.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Insulin resistance
EvidenceScore™ Strong | EvidenceScore™ 76.8 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 5 supporting studies with consistent results and a positive effect signal.
Limitations
Ketogenic Diets may improve Fasting Glucose.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Fasting Plasma Glucose (FPG)
EvidenceScore™ Strong | EvidenceScore™ 79.0 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on 3 supporting studies with generally consistent results and a positive effect signal.
Limitations
Ketogenic Diets may improve HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 78.6 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on 4 supporting studies with consistent results and a positive effect signal.
Limitations
Ketogenic Diets appears to improve Quality of Life Outcomes.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Quality of life
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 3 supporting studies with consistent results and a positive effect signal.
Limitations
Next steps
Choose a next path through related evidence topics, Evidence Explorer views, and research summaries.
Follow the topics this study contributes to.
Open broader Evidence Explorer views for this relationship.
Read related research summaries.
Centrada en la evidencia, no en la publicidad.
Tus datos siempre están protegidos.
Se agregan nuevos estudios todos los días.
