Last updated May 4, 2026
Key finding
A 12-week study in 332 type 2 diabetes patients found that Boscisucrophage (BSP), a natural Boscia senegalensis seed extract, significantly lowered blood glucose and HbA1c when added to existing therapy.
This study tested Boscisucrophage (BSP), a supplement made from Boscia senegalensis seeds, in 332 people with type 2 diabetes who still had high blood sugar despite medication. After 12 weeks of taking 350 mg capsules three times daily, most patients had lower blood glucose and HbA1c, along with increased urine glucose excretion.
Quick read
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EvidenceScore™
Moderate
Study type
non-randomized clinical trial (non-RCT or NRCT)
Follow-up
Short-Term (≤3 mo)
Risk of bias
High Risk
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Plain-language summary
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Study focus
A 12-week study in 332 type 2 diabetes patients found that Boscisucrophage (BSP), a natural Boscia senegalensis seed extract, significantly lowered blood glucose and HbA1c when added to existing therapy.
Published in
Publication details and source links for this paper.
Eto B, Elrherabi A, Nasr FA, et al. Boscisucrophage: A Natural SGLT1/2 Inhibitor From Boscia senegalensis for Managing Type 2 Diabetes. Food Sci Nutr. 2026;14(3):e71621.
↓ Blood glucose (significant reduction observed after 1 week of treatment)
↓ HbA1c (below 7% after 60 days of treatment)
↑ Urine glucose excretion via SGLT1/SGLT2 inhibition
Evidence network
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This study contributes evidence to Boscisucrophage (Boscia senegalensis extract) and Blood glucose, Body weight, HbA1c, and 1 more.
This study contributes evidence to
Primary intervention
Boscisucrophage (Boscia senegalensis extract)
Primary outcomes
Evidence topics
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
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Evidence network role
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Contributes evidence
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Contributes evidence
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Contributes evidence
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Primary evidence
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matched_outcome
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Core evidence
The primary outcomes reported in this study.
Boscisucrophage (Boscia senegalensis extract) → Blood glucose
Boscisucrophage (Boscia senegalensis extract) → Blood glucose
Boscisucrophage (Boscia senegalensis extract) → Body weight
Boscisucrophage (Boscia senegalensis extract) → Body weight
Boscisucrophage (Boscia senegalensis extract) → HbA1c
Boscisucrophage (Boscia senegalensis extract) → HbA1c
Boscisucrophage (Boscia senegalensis extract) → Urine glucose excretion (UGE)
Boscisucrophage (Boscia senegalensis extract) → Urine glucose excretion (UGE)
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People with type 2 diabetes who have difficulty controlling blood sugar with oral medications alone, particularly in regions where Boscia senegalensis is traditionally used as a food and medicine source.
This was a preliminary single-arm study without a control group, so the results may be influenced by other factors like increased attention or natural disease changes. Randomized controlled trials are needed before firm conclusions can be drawn about BSP's effectiveness compared to standard treatments.
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Boscisucrophage (Boscia senegalensis extract) and Fasting Glucose, Boscisucrophage (Boscia senegalensis extract) and Body Weight.
This study contributes to the evidence on the following intervention-outcome relationships.
Curated evidence collections and hubs this study is part of.
All studies measuring Body Weight
Measures Body Weight as a key outcome.
All studies on Boscisucrophage (Boscia senegalensis extract)
Contributes to Boscisucrophage (Boscia senegalensis extract) evidence base.
All studies measuring Fasting Glucose
Measures Fasting Glucose as a key outcome.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Boscisucrophage (Boscia senegalensis extract) appears to improve Blood glucose.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Blood glucose
EvidenceScore™ Emerging | EvidenceScore™ 52.6 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Boscisucrophage (Boscia senegalensis extract) appears to improve HbA1c.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 52.6 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Boscisucrophage (Boscia senegalensis extract) appears to improve Urine glucose excretion (UGE).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Urine glucose excretion (UGE)
EvidenceScore™ Emerging | EvidenceScore™ 52.6 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Boscisucrophage (Boscia senegalensis extract) may improve Body weight.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Body weight
EvidenceScore™ Emerging | EvidenceScore™ 52.6 | weak positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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