Intensive lifestyle program was linked to diabetes remission in Indian adults
Key takeaway:
In a retrospective Indian cohort, 31.2% of adults with type 2 diabetes achieved remission after a one-year multidisciplinary lifestyle program.
Study at a glance
What was studied
A one-year online intensive lifestyle intervention for type 2 diabetes remission.
Study type
non-randomized clinical trial (non-RCT or NRCT)
duration
Medium-Term (3–12 mo)
Intervention
Multidisciplinary lifestyle intervention for type 2 diabetes remission
Outcomes
Diabetes remission, HbA1c, Body weight, BMI, Fasting insulin levels, Insulin resistance
Funding
Non-industry sponsored
Main effects
Diabetes remission ↑: 31.2% achieved remission after the one-year program
HbA1c ↓: remission participants had larger HbA1c reductions than non-remission participants
Body weight and insulin resistance ↓: larger reductions were seen in the remission group
Evidence Summary
| Intervention | Outcome | Measured Change | Study Effect |
|---|---|---|---|
 Multidisciplinary lifestyle intervention for type 2 diabetes remission (Behavioral & Lifestyle) |  BMI (Weight & Anthropometrics) | Decrease | Mixed |
Multidisciplinary lifestyle intervention for type 2 diabetes remission (Behavioral & Lifestyle) | Body weight (Weight & Anthropometrics) | Decrease | Mixed |
Multidisciplinary lifestyle intervention for type 2 diabetes remission (Behavioral & Lifestyle) |  Diabetes remission (Glycemic Control) | Increase | Mixed |
Multidisciplinary lifestyle intervention for type 2 diabetes remission (Behavioral & Lifestyle) |  Fasting insulin levels (Metabolic Health) | Decrease | Mixed |
Multidisciplinary lifestyle intervention for type 2 diabetes remission (Behavioral & Lifestyle) | HbA1c (Glycemic Control) | Decrease | Mixed |
Multidisciplinary lifestyle intervention for type 2 diabetes remission (Behavioral & Lifestyle) | Insulin resistance (Metabolic Health) | Decrease | Mixed |
Unlock Full Evidence Analysis
Create a free account to access effectiveness ratings, evidence strength and depth scores, consistency analysis, and direct links to all supporting studies.
Evidence Suggest
- The cohort included 2,384 adults with type 2 diabetes from an online intervention program in India.
- Remission occurred in 744 participants, or 31.2% of the analyzed cohort.
- The study itself states that its retrospective design and lack of control group limit attribution to the intervention.
Who this applies to
Adults aged 30–75 with type 2 diabetes in India
Keep in Mind
This was not a randomized trial.
Between the Lines
- Retrospective design with no parallel control group.
- Subscription-based program may select for higher socioeconomic status or motivation.
- Participants with limited follow-up or missing data were excluded.
- Adherence was supported but not objectively measured.
Unlock Full Analysis
Create a free account to unlock the bias score, detailed effectiveness analysis, and clinical outcomes for this study.
Journal Reference
Tripathi P, Kadam N, Kathrikolly T, et al. Type 2 diabetes remission and its predictors in an Indian cohort: A retrospective analysis of an intensive lifestyle intervention program. PLOS One. 2025. doi:10.1371/journal.pone.0333114
Connected Evidence
Discover how this study fits into the broader diabetes evidence landscape.
This study contributes to evidence on Multidisciplinary lifestyle intervention for type 2 diabetes remission and BMI, Multidisciplinary lifestyle intervention for type 2 diabetes remission and Body weight.
Related evidence relationships
Explore in Evidence ArchiveThis study contributes to the evidence on the following intervention–outcome relationships.
Included in these evidence collections
Curated evidence collections and hubs this study is part of.
BMI Evidence Hub
All studies measuring BMI
Measures BMI as a key outcome.
Body weight Evidence Hub
All studies measuring Body weight
Measures Body weight as a key outcome.
Multidisciplinary lifestyle intervention for type 2 diabetes remission Evidence Hub
All studies on Multidisciplinary lifestyle intervention for type 2 diabetes remission
Contributes to Multidisciplinary lifestyle intervention for type 2 diabetes remission evidence base.
Explore more in the evidence archive
Jump to pre-filtered views in the evidence archive.
All studies on Multidisciplinary lifestyle intervention for type 2 diabetes remission and BMI
2 results
All studies on Multidisciplinary lifestyle intervention for type 2 diabetes remission and Body weight
2 results
All studies on Multidisciplinary lifestyle intervention for type 2 diabetes remission
2 results
All studies measuring BMI
2 results
All studies measuring Body weight
2 results
Questions this evidence helps answer
Key clinical and research questions this study contributes to.
Does multidisciplinary lifestyle intervention for type 2 diabetes remission improve BMI?
Based on connected evidence for Multidisciplinary lifestyle intervention for type 2 diabetes remission and BMI.
Does multidisciplinary lifestyle intervention for type 2 diabetes remission affect Body weight in people with diabetes?
Exploring evidence on Multidisciplinary lifestyle intervention for type 2 diabetes remission and Body weight outcomes.
No ads. No tracking.
Focused on evidence, not advertising.
Secure & private
Your data is always protected.
Always up to date
New studies added every day.