Last updated May 29, 2026
Key finding
In a retrospective Indian cohort, 31.2% of adults with type 2 diabetes achieved remission after a one-year multidisciplinary lifestyle program.
This study reviewed records from adults with type 2 diabetes who joined a one-year online lifestyle program in India. About one-third achieved diabetes remission, but the study had no control group, so the results show association rather than definitive proof that the program caused remission.
Quick read
The essential study design details in one scan.
EvidenceScore™
Low
Study type
non-randomized clinical trial (non-RCT or NRCT)
Follow-up
Medium-Term (3–12 mo)
Risk of bias
High Risk
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
In a retrospective Indian cohort, 31.2% of adults with type 2 diabetes achieved remission after a one-year multidisciplinary lifestyle program.
Published in
Publication details and source links for this paper.
Tripathi P, Kadam N, Kathrikolly T, et al. Type 2 diabetes remission and its predictors in an Indian cohort: A retrospective analysis of an intensive lifestyle intervention program. PLOS One. 2025. doi:10.1371/journal.pone.0333114
Diabetes remission ↑: 31.2% achieved remission after the one-year program
HbA1c ↓: remission participants had larger HbA1c reductions than non-remission participants
Body weight and insulin resistance ↓: larger reductions were seen in the remission group
Evidence network
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This study contributes evidence to Intensive lifestyle intervention for type 2 diabetes remission and BMI, Body weight, Diabetes remission, and 3 more.
This study contributes evidence to
Primary intervention
Intensive lifestyle intervention for type 2 diabetes remission
Primary outcomes
Evidence topics
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
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Related topics
6
Evidence pairs
510
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Contributes evidence
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Contributes evidence
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Contributes evidence
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Contributes evidence
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Primary evidence
Evidence relationship
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Evidence relationship
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Core evidence
The primary outcomes reported in this study.
Intensive lifestyle intervention for type 2 diabetes remission → BMI
Intensive lifestyle intervention for type 2 diabetes remission → BMI
Intensive lifestyle intervention for type 2 diabetes remission → Body weight
Intensive lifestyle intervention for type 2 diabetes remission → Body weight
Intensive lifestyle intervention for type 2 diabetes remission → Diabetes remission
Intensive lifestyle intervention for type 2 diabetes remission → Diabetes remission
Intensive lifestyle intervention for type 2 diabetes remission → Fasting insulin levels
Intensive lifestyle intervention for type 2 diabetes remission → Fasting insulin levels
Intensive lifestyle intervention for type 2 diabetes remission → HbA1c
Intensive lifestyle intervention for type 2 diabetes remission → HbA1c
Intensive lifestyle intervention for type 2 diabetes remission → Insulin resistance
Intensive lifestyle intervention for type 2 diabetes remission → Insulin resistance
Evidence Library
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Adults aged 30–75 with type 2 diabetes in India
This was not a randomized trial.
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Diabetes Self-Management Education and Support (DSMES) Programs and HbA1c, Diabetes Self-Management Education and Support (DSMES) Programs and Body Mass Index.
This study contributes to the evidence on the following intervention-outcome relationships.
Behavioral & Lifestyle
Behavioral & Lifestyle
Behavioral & Lifestyle
Curated evidence collections and hubs this study is part of.
All studies on Diabetes Self-Management Education and Support (DSMES) Programs
Contributes to Diabetes Self-Management Education and Support (DSMES) Programs evidence base.
All studies measuring HbA1c
Measures HbA1c as a key outcome.
All studies measuring Body Mass Index
Measures Body Mass Index as a key outcome.
All studies measuring Body Weight
Measures Body Weight as a key outcome.
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4 results
3 results
4 results
4 results
3 results
Generated from the study's connected evidence using Evidence Intelligence™.
Diabetes Self-Management Education and Support (DSMES) Programs may improve HbA1c.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Moderate | EvidenceScore™ 73.2 | weak positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 30 supporting studies with generally consistent results and a positive effect signal.
Limitations
Diabetes Self-Management Education and Support (DSMES) Programs may improve Body Mass Index.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Ranked evidence signals
BMI
EvidenceScore™ Moderate | EvidenceScore™ 69.7 | moderate positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
Diabetes Self-Management Education and Support (DSMES) Programs appears to improve Body Weight.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Body weight
EvidenceScore™ Moderate | EvidenceScore™ 60.2 | moderate positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 6 supporting studies with consistent results and a positive effect signal.
Limitations
Diabetes Self-Management Education and Support (DSMES) Programs may improve Insulin Resistance.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Fasting insulin levels
EvidenceScore™ Moderate | EvidenceScore™ 60.2 | neutral | ConsistencyScore™ Mixed | 1 study
Insulin resistance
EvidenceScore™ Emerging | EvidenceScore™ 56.8 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 4 supporting studies with consistent results and a positive effect signal.
Limitations
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