Research Summary
Analyzed using Evidence Intelligence™

CBTI improves sleep regularity and reduces anxiety in T2D patients

Last updated July 11, 2026

Key finding

CBTI group had significantly improved sleep regularity compared to the HE group (mean difference -21.84 minutes (95% CI -41.64, -2.05, p=0.031).

This study evaluated the impact of Cognitive Behavioral Therapy for Insomnia (CBTI) on sleep regularity and anxiety in individuals with Type 2 Diabetes. CBTI showed significant improvements in sleep regularity and anxiety symptoms compared to Health Education (HE).

Quick read

Study at a glance

The essential study design details in one scan.

EvidenceScore™

Moderate

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Risk of bias

Some Concerns

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Plain-language summary

What this paper says

A plain-language read of the study’s main message and where it applies.

Study focus

This study evaluated the impact of Cognitive Behavioral Therapy for Insomnia (CBTI) on sleep regularity and anxiety in individuals with Type 2 Diabetes. CBTI showed significant improvements in sleep regularity and anxiety symptoms compared to Health Education (HE).

Clinical relevance

Improving sleep regularity and reducing anxiety are crucial for managing Type 2 Diabetes effectively. This study suggests that CBTI could be a beneficial intervention for this population, potentially leading to better overall health outcomes and quality of life.

Keep in mind

Self-reported sleep quality did not differ between groups. The study may have limited generalizability due to specific population characteristics. Effectiveness of interventions beyond the 8-week period remains unclear.

Published in

Journal Reference

Publication details and source links for this paper.

Similan K, Sirimon R, Chutintorn S, et al. Cognitive Behavioral Therapy for Insomnia Improves Sleep Regularity and Reduces Anxiety in Type 2 Diabetes. Journal of the Endocrine Society. 2025;9(Suppl 1):bvaf149.1237. doi:10.1210/jendso/bvaf149.1237

Main Effects

CBTI group showed significantly improved sleep regularity compared to HE group.

CBTI group had a greater reduction in anxiety symptoms than HE group.

CBTI group experienced a greater reduction in fasting plasma glucose levels compared to HE group.

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Behavioral counseling, Remote nutrition education on low-carbohydrate diet and Anxiety score, Fasting Plasma Glucose (FPG), Sleep quality, and 1 more.

Primary intervention

Behavioral counseling

Primary outcomes

  • Anxiety score
  • Fasting Plasma Glucose (FPG)
  • Sleep quality

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

8
Evidence pairs
8
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

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Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 68

2

Related topics

8

Evidence pairs

463

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 8 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Add related evidence to your Evidence Tracker

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Primary evidence

Evidence relationship

Diabetes Self-Management Education and Support (DSMES) Programs and Fasting Glucose

Related evidence

Evidence relationship

Diabetes Self-Management Education and Support (DSMES) Programs and Quality of Life Outcomes

Save evidence

Evidence relationship

Diabetes Self-Management Education and Support (DSMES) Programs and Mental Health

Save evidence

Core evidence

Study findings

The primary outcomes reported in this study.

Anxiety score

Behavioral counseling → Anxiety score

Behavioral counseling → Anxiety score

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
100
Very Positive
ConsistencyScore™
100
consistent
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Fasting Plasma Glucose (FPG)

Behavioral counseling → Fasting Plasma Glucose (FPG)

Behavioral counseling → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Sleep quality

Behavioral counseling → Sleep quality

Behavioral counseling → Sleep quality

Evidence Intelligence™
EvidenceScore™
Moderate
Score 69 · Based on 2 studies
ImpactScore™
75
Positive
ConsistencyScore™
35
mixed
Supporting studies: Based on 2 studies
Add to Evidence Tracker

Sleep regularity

Behavioral counseling → Sleep regularity

Behavioral counseling → Sleep regularity

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
100
Very Positive
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Anxiety score

Remote nutrition education on low-carbohydrate diet → Anxiety score

Remote nutrition education on low-carbohydrate diet → Anxiety score

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Fasting Plasma Glucose (FPG)

Remote nutrition education on low-carbohydrate diet → Fasting Plasma Glucose (FPG)

Remote nutrition education on low-carbohydrate diet → Fasting Plasma Glucose (FPG)

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Sleep quality

Remote nutrition education on low-carbohydrate diet → Sleep quality

Remote nutrition education on low-carbohydrate diet → Sleep quality

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Sleep regularity

Remote nutrition education on low-carbohydrate diet → Sleep regularity

Remote nutrition education on low-carbohydrate diet → Sleep regularity

Evidence Intelligence™
EvidenceScore™
Emerging
Score 59 · Based on 1 study
ImpactScore™
50
Neutral
ConsistencyScore™
unclear
Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence Tracker

Evidence Library

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evidence suggest

Evidence Suggest

  • CBTI improved sleep regularity by 21.84 minutes (p=0.031).
  • CBTI reduced anxiety symptoms significantly compared to HE.
  • CBTI led to a decrease in fasting plasma glucose levels by 34.27 mg/dL (p=0.001).
who this applies

Who this applies to

  • Adults diagnosed with Type 2 Diabetes.
  • Individuals experiencing insomnia and anxiety.
keep in mind

Keep in Mind

  • Results are specific to the 8-week intervention period.
  • Findings may not apply to individuals outside the study demographics.
  • Further research is needed to assess long-term effects of CBTI.
between the lines

Between the Lines

  • Self-reported sleep quality did not differ between groups.
  • The study may have limited generalizability due to specific population characteristics.
  • Effectiveness of interventions beyond the 8-week period remains unclear.

Evidence Library

Build your evidence library

Save research, organize studies, and quickly find important evidence again.

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Diabetes Self-Management Education and Support (DSMES) Programs and Mental Health, Diabetes Self-Management Education and Support (DSMES) Programs and Quality of Life Outcomes.

Related evidence relationships

Explore in Evidence Explorer

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Diabetes Self-Management Education and Support (DSMES) Programs improve fasting glucose?

Strong Evidence

Diabetes Self-Management Education and Support (DSMES) Programs may improve Fasting Glucose.

ConsistencyScore™: Results are mixed and should be interpreted cautiously.

Evidence caveat: The available evidence reports mixed findings.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is cautious because the available studies report mixed findings.

Limitations

  • Population details are unavailable.
20 supporting studiesUpdated: Aug 2026

Does Diabetes Self-Management Education and Support (DSMES) Programs improve quality of life outcomes?

Strong Evidence

Diabetes Self-Management Education and Support (DSMES) Programs may improve Quality of Life Outcomes.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    Sleep quality

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study

Why this answer: This answer is based on 13 supporting studies with generally consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
13 supporting studiesUpdated: Aug 2026

Does Diabetes Self-Management Education and Support (DSMES) Programs improve mental health?

Strong Evidence

Diabetes Self-Management Education and Support (DSMES) Programs may improve Mental Health.

ConsistencyScore™: Results are generally consistent across studies.

Ranked evidence signals

  1. 1

    Anxiety score

    EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study

Why this answer: This answer is based on 12 supporting studies with generally consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
12 supporting studiesUpdated: Aug 2026

Does Low-Carbohydrate Diet Education improve fasting glucose?

Strong Evidence

Low-Carbohydrate Diet Education appears to improve Fasting Glucose.

ConsistencyScore™: Results are consistent across studies.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study

Why this answer: This answer is based on 9 supporting studies with consistent results and a positive effect signal.

Limitations

  • Population details are unavailable.
9 supporting studiesUpdated: Aug 2026
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