Research Summary
Analyzed using Evidence Intelligence™

Chromium supplementation improves glycemic control in type 2 diabetes.

Key finding

HbA1c decreased significantly from 10.4 ± 2.4 to 7.2 ± 1.7 (p < 0.001)

This study evaluated the effects of chromium supplementation on glycemic control in patients with type 2 diabetes, finding significant improvements in HbA1c and fasting plasma glucose levels.

Evidence strength

Moderate confidence

Study type

RCTs

Follow-up

Extended (5–20+ y)

Some Concerns bias
Last updated July 6, 2026

Quick read

Study at a glance

The essential study design details in one scan.

Population

Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes

Intervention

Chromium supplementation

Study type

RCTs

Follow-up

Extended (5–20+ y)

Primary outcome

HbA1c

Comparator

Standard drug treatment

Plain-language summary

What this paper says

A plain-language read of the study's main message and where it applies.

Study focus

This study evaluated the effects of chromium supplementation on glycemic control in patients with type 2 diabetes, finding significant improvements in HbA1c and fasting plasma glucose levels.

Clinical relevance

These findings suggest that chromium supplementation could be a beneficial adjunct therapy for managing blood sugar levels and improving cholesterol profiles in patients with type 2 diabetes. This could lead to better overall health outcomes and reduced risk of diabetes-related complications.

Keep in mind

The study did not assess long-term effects of chromium supplementation. Sample size and demographic diversity were not specified. No placebo control group was mentioned.

Published in

Journal Reference

Publication details and source links for this paper.

Fatima A. The Impact of Chromium Supplementation on Glycemic Control in Patients with Type 2 Diabetes: A Randomized Controlled Trial. Journal of Medicine and Life. 2023;16(8):1178-1182. doi:10.25122/jml-2023-0081

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Main Effects

HbA1c decreased significantly from 10.4 ± 2.4 to 7.2 ± 1.7 (p < 0.001).

Fasting plasma glucose decreased significantly (p < 0.001).

Total cholesterol decreased significantly (p = 0.002).

HDL levels increased significantly (p = 0.006).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Chromium supplementation and Fasting Plasma Glucose (FPG), HDL cholesterol, HbA1c, and 2 more.

Primary intervention

Chromium supplementation

Primary outcomes

  • Fasting Plasma Glucose (FPG)
  • HDL cholesterol
  • HbA1c

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

5
Evidence pairs
5
Relationships
2
Evidence topics
contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 64

2

Related topics

5

Evidence pairs

270

Related studies

High relevance in at least one topic

Why it is useful

  • Contributes to 5 evidence relationships
  • Includes primary outcome data
  • Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Contributes evidence

Core evidence

Study findings

The primary outcomes reported in this study.

StrongDecrease

Fasting Plasma Glucose (FPG)

Chromium supplementation → Fasting Plasma Glucose (FPG)

Chromium supplementation → Fasting Plasma Glucose (FPG)

Evidence profile

StrongDecreaseGlycemic Control
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StrongDecrease

HbA1c

Chromium supplementation → HbA1c

Chromium supplementation → HbA1c

Evidence profile

StrongDecreaseGlycemic Control
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StrongIncrease

HDL cholesterol

Chromium supplementation → HDL cholesterol

Chromium supplementation → HDL cholesterol

Evidence profile

StrongIncreaseMetabolic Health
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StrongDecrease

Total cholesterol

Chromium supplementation → Total cholesterol

Chromium supplementation → Total cholesterol

Evidence profile

StrongDecreaseMetabolic Health
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NoneNo Change

Triglycerides

Chromium supplementation → Triglycerides

Chromium supplementation → Triglycerides

Evidence profile

NoneNo ChangeMetabolic Health
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evidence suggest

Evidence Suggest

  • HbA1c levels dropped by 3.2 percentage points (p < 0.001).
  • Fasting plasma glucose decreased by 20.9 mg/dL (p < 0.001).
  • Total cholesterol levels decreased by 29.8 mg/dL (p = 0.002).
who this applies

Who this applies to

  • Adults diagnosed with type 2 diabetes.
  • Patients seeking additional methods to manage blood sugar levels.
keep in mind

Keep in Mind

  • Results may not apply to populations outside the study demographics.
  • The study did not measure long-term outcomes or side effects.
  • Further research is needed to confirm these findings.
between the lines

Between the Lines

  • The study did not assess long-term effects of chromium supplementation.
  • Sample size and demographic diversity were not specified.
  • No placebo control group was mentioned.

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Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Chromium supplementation and Fasting Glucose, Chromium supplementation and HbA1c.

Related evidence relationships

Explore in Evidence Archive

This study contributes to the evidence on the following intervention-outcome relationships.

Questions answered by this study

Generated from the study's connected evidence using Evidence Intelligence™.

Does Chromium supplementation improve fasting plasma glucose (fpg)?

Emerging Evidence

Chromium supplementation appears to improve Fasting Plasma Glucose (FPG).

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Fasting Plasma Glucose (FPG)

    EvidenceScore™ Emerging | EvidenceScore™ 52.9 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Chromium supplementation improve hdl cholesterol?

Emerging Evidence

Chromium supplementation appears to improve HDL cholesterol.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    HDL cholesterol

    EvidenceScore™ Emerging | EvidenceScore™ 52.9 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Chromium supplementation improve HbA1c?

Emerging Evidence

Chromium supplementation appears to improve HbA1c.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    HbA1c

    EvidenceScore™ Emerging | EvidenceScore™ 52.9 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026

Does Chromium supplementation improve total cholesterol?

Emerging Evidence

Chromium supplementation appears to improve Total cholesterol.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

  1. 1

    Total cholesterol

    EvidenceScore™ Emerging | EvidenceScore™ 52.9 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

  • Only one supporting study is available.
  • Consistency cannot yet be determined.
  • Population details are unavailable.
1 supporting studyUpdated: Jul 2026
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