Last updated July 6, 2026
Key finding
HbA1c levels decreased below prediabetes thresholds.
This study evaluated the impact of a dietary fiber supplement (YMETA) on gut health and metabolic function in prediabetic adults, finding improvements in gut microbiota diversity.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
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Study focus
This study evaluated the impact of a dietary fiber supplement (YMETA) on gut health and metabolic function in prediabetic adults, finding improvements in gut microbiota diversity.
Understanding the effects of dietary fiber on gut health is crucial for managing prediabetes. Improved gut microbiota diversity may contribute to better metabolic health, potentially reducing the risk of progressing to type 2 diabetes. However, the lack of significant changes in blood sugar levels suggests that more research is needed to determine the full benefits of dietary fiber supplementation in this population.
The study's sample size may limit the generalizability of the findings. No significant changes were observed in key metabolic markers like HbA1c and FPG. The trial duration may not have been long enough to capture long-term effects.
Published in
Publication details and source links for this paper.
Beyda B, Monica B, Silvia T, et al. The Effects of a Dietary Fiber Supplement on Gut Health and Metabolic Function in Prediabetic Adults: A Randomized Controlled Trial. Nutrients. 2024;16(14):2205. doi:10.3390/nu16142205
Alpha diversity of gut microbiota significantly increased in the YMETA group at week 12 (1.2 units, p = 0.04).
Butyrate-producing bacteria showed a significant increase in the intervention group.
Fasting plasma glucose levels decreased, but not below prediabetes thresholds.
Triglycerides levels slightly reduced, but this change was not statistically significant (p = 0.55).
Evidence network
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This study contributes evidence to Dietary fibre supplement (YMETA) and Butyrate-producing bacteria, Fasting Plasma Glucose (FPG), Gastrointestinal symptoms frequency, and 5 more.
This study contributes evidence to
Primary intervention
Dietary fibre supplement (YMETA)
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
2
Related topics
8
Evidence pairs
777
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Contributes evidence
Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Related evidence
Evidence topic
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Core evidence
The primary outcomes reported in this study.
Dietary fibre supplement (YMETA) → Butyrate-producing bacteria
Dietary fibre supplement (YMETA) → Butyrate-producing bacteria
Dietary fibre supplement (YMETA) → Fasting Plasma Glucose (FPG)
Dietary fibre supplement (YMETA) → Fasting Plasma Glucose (FPG)
Dietary fibre supplement (YMETA) → Gastrointestinal symptoms frequency
Dietary fibre supplement (YMETA) → Gastrointestinal symptoms frequency
Dietary fibre supplement (YMETA) → Gut microbiota diversity
Dietary fibre supplement (YMETA) → Gut microbiota diversity
Dietary fibre supplement (YMETA) → HDL cholesterol
Dietary fibre supplement (YMETA) → HDL cholesterol
Dietary fibre supplement (YMETA) → Total cholesterol
Dietary fibre supplement (YMETA) → Total cholesterol
Dietary fibre supplement (YMETA) → Triglycerides
Dietary fibre supplement (YMETA) → Triglycerides
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Dietary fibre supplement (YMETA) and Fasting Glucose, Dietary fibre supplement (YMETA) and HbA1c.
This study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Curated evidence collections and hubs this study is part of.
All studies on Dietary fibre supplement (YMETA)
Contributes to Dietary fibre supplement (YMETA) evidence base.
All studies measuring Fasting Glucose
Measures Fasting Glucose as a key outcome.
All studies measuring HbA1c
Measures HbA1c as a key outcome.
All studies measuring Adipokine and Angiogenic Markers
Measures Adipokine and Angiogenic Markers as a key outcome.
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Published within the last 2 years.
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2 results
2 results
2 results
2 results
2 results
Generated from the study's connected evidence using Evidence Intelligence™.
Dietary fibre supplement (YMETA) appears to improve Fasting Plasma Glucose (FPG).
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
Fasting Plasma Glucose (FPG)
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Dietary fibre supplement (YMETA) appears to improve HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Dietary fibre supplement (YMETA) appears to improve Butyrate-producing bacteria.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Butyrate-producing bacteria
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Dietary fibre supplement (YMETA) appears to improve Gut microbiota diversity.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Gut microbiota diversity
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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