Research Summary

Analyzed using Evidence Intelligence™

Dietary Fiber Supplement Improves Metabolic Function in Prediabetes

Key finding

HbA1c levels decreased below prediabetes thresholds.

This study evaluated the impact of a dietary fiber supplement (YMETA) on gut health and metabolic function in prediabetic adults, finding improvements in gut microbiota diversity.

Evidence strength

Moderate confidence

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Some Concerns bias

Last updated July 6, 2026

Quick read

Study at a glance

The essential study design details in one scan.

Population

Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes

Intervention

Dietary fibre supplement (YMETA)

Study type

RCTs

Follow-up

Medium-Term (3–12 mo)

Primary outcome

Glycated hemoglobin (HbA1c)

Comparator

Placebo

Plain-language summary

What this paper says

A plain-language read of the study's main message and where it applies.

Study focus

This study evaluated the impact of a dietary fiber supplement (YMETA) on gut health and metabolic function in prediabetic adults, finding improvements in gut microbiota diversity.

Clinical relevance

Understanding the effects of dietary fiber on gut health is crucial for managing prediabetes. Improved gut microbiota diversity may contribute to better metabolic health, potentially reducing the risk of progressing to type 2 diabetes. However, the lack of significant changes in blood sugar levels suggests that more research is needed to determine the full benefits of dietary fiber supplementation in this population.

Keep in mind

The study's sample size may limit the generalizability of the findings. No significant changes were observed in key metabolic markers like HbA1c and FPG. The trial duration may not have been long enough to capture long-term effects.

Published in

Journal Reference

Publication details and source links for this paper.

Beyda B, Monica B, Silvia T, et al. The Effects of a Dietary Fiber Supplement on Gut Health and Metabolic Function in Prediabetic Adults: A Randomized Controlled Trial. Nutrients. 2024;16(14):2205. doi:10.3390/nu16142205

View DOI View on PubMed View on PMC

Save this study and add notes to your research library.

Main Effects

Alpha diversity of gut microbiota significantly increased in the YMETA group at week 12 (1.2 units, p = 0.04).

Butyrate-producing bacteria showed a significant increase in the intervention group.

Fasting plasma glucose levels decreased, but not below prediabetes thresholds.

Triglycerides levels slightly reduced, but this change was not statistically significant (p = 0.55).

Evidence network

How this study fits

Understand where this research contributes within the broader evidence network.

Evidence Context

This study contributes evidence to Dietary fibre supplement (YMETA) and Butyrate-producing bacteria, Fasting Plasma Glucose (FPG), Gastrointestinal symptoms frequency, and 5 more.

This study contributes evidence to

Intervention

Dietary fibre supplement (YMETA)

Outcome

Butyrate-producing bacteria

Evidence topic

Glycemic Control

Primary intervention

Dietary fibre supplement (YMETA)

Primary outcomes

Butyrate-producing bacteria
Fasting Plasma Glucose (FPG)
Gastrointestinal symptoms frequency

Evidence topics

Glycemic Control HbA1c Reduction

Primary intervention

Dietary fibre supplement (YMETA)

Primary outcomes

Butyrate-producing bacteria Fasting Plasma Glucose (FPG)Gastrointestinal symptoms frequency

Evidence relationships

Intervention and outcome relationships this study adds to the evidence network.

Evidence pairs

Relationships

Evidence topics

contributes_evidence

Editorial context

Why this study matters

See why this paper is useful beyond its individual results.

Evidence network role

This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.

Moderate contributionModerate confidenceNetwork score: 64

Why it is useful

Contributes to 8 evidence relationships
Includes primary outcome data
Linked to 2 direct semantic evidence topics

Topic contributions

Evidence topic

Contributes evidence

Evidence topic

Dietary fibre supplement (YMETA) → Triglycerides

Evidence profile

NoneDecreaseMetabolic Health

Unlock full evidence details

Unlock full evidence analysis

Create a free account to access effectiveness ratings, evidence strength and depth scores, consistency analysis, and direct links to all supporting studies.

Evidence Suggest

Alpha diversity increased by 1.2 units in the YMETA group (p = 0.04).
No significant changes in gastrointestinal symptoms were observed.
Triglycerides decreased by -0.13 mmol/L, but not significantly (p = 0.55).

Who this applies to

Adults aged 18-65 with prediabetes.
Individuals seeking dietary interventions to improve gut health.

Keep in Mind

Results may not apply to populations outside the study's demographic.
The lack of significant metabolic changes suggests further research is needed.
The study did not measure long-term outcomes beyond 12 weeks.

Between the Lines

The study's sample size may limit the generalizability of the findings.
No significant changes were observed in key metabolic markers like HbA1c and FPG.
The trial duration may not have been long enough to capture long-term effects.

Unlock Full Analysis

Create a free account to unlock the bias score, detailed effectiveness analysis, and clinical outcomes for this study.

Already have an account?

Connected Evidence

Explore related studies, evidence collections, and research questions.

Relationships organized using the Dediabetes Evidence Intelligence™ framework.

This study contributes to evidence on Dietary fibre supplement (YMETA) and Butyrate-producing bacteria, Dietary fibre supplement (YMETA) and Fasting Glucose.

Related evidence relationships

Explore in Evidence Archive

This study contributes to the evidence on the following intervention-outcome relationships.

Dietary fibre supplement (YMETA)Butyrate-producing bacteria

Supplements

1 studies

Detailed evidence

Dietary fibre supplement (YMETA)Fasting Glucose

Supplements

Latest published studies

recency_collection

Published within the last 2 years.

Generated from the study's connected evidence using Evidence Intelligence™.

Does Dietary fibre supplement (YMETA) improve butyrate-producing bacteria?

Emerging Evidence

Dietary fibre supplement (YMETA) appears to improve Butyrate-producing bacteria.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

1
Butyrate-producing bacteria
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

Only one supporting study is available.
Consistency cannot yet be determined.
Population details are unavailable.

View Full Evidence

Does Dietary fibre supplement (YMETA) improve fasting plasma glucose (fpg)?

Emerging Evidence

Dietary fibre supplement (YMETA) appears to improve Fasting Plasma Glucose (FPG).

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

1
Fasting Plasma Glucose (FPG)
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

Only one supporting study is available.
Consistency cannot yet be determined.
Population details are unavailable.

View Full Evidence

Does Dietary fibre supplement (YMETA) improve gut microbiota diversity?

Emerging Evidence

Dietary fibre supplement (YMETA) appears to improve Gut microbiota diversity.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

1
Gut microbiota diversity
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

Only one supporting study is available.
Consistency cannot yet be determined.
Population details are unavailable.

View Full Evidence

Does Dietary fibre supplement (YMETA) improve HbA1c?

Emerging Evidence

Dietary fibre supplement (YMETA) appears to improve HbA1c.

ConsensusScore™: Consistency cannot yet be determined from the available evidence.

Ranked evidence signals

1
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study

Why this answer: This answer is based on a single supporting study.

Limitations

Only one supporting study is available.
Consistency cannot yet be determined.
Population details are unavailable.

View Full Evidence

Learn how Evidence Intelligence™ works

Next steps

Continue your research

Choose a next path through related evidence topics, archive views, and research summaries.

Evidence topics

Follow the topics this study contributes to.

Glycemic Control Evidence Hub HbA1c Reduction Evidence Hub

Explore in archive

Open broader archive views for this relationship.

All studies on Dietary fibre supplement (YMETA) and Fasting Plasma Glucose (FPG)All studies on Dietary fibre supplement (YMETA) and HbA1c All studies on Dietary fibre supplement (YMETA) and Butyrate-producing bacteria All studies on Dietary fibre supplement (YMETA) and Gut microbiota diversity

Related research

Read related research summaries.

HRS-7535 improves glycemic control in adults with type 2 diabetes Mediterranean ketogenic eating matched VLCKD for weight loss over 3 months Natural products may improve glycemic control in type 2 diabetes Newer diabetes drugs show stronger weight and blood sugar benefits in prediabetes Chromium supplementation improves glycemic control in type 2 diabetes.

No ads. No tracking.

Focused on evidence, not advertising.

Secure & private

Your data is always protected.

Always up to date

New studies added every day.