Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerResearch Summary
Analyzed using Evidence Intelligence™
Natural products may improve glycemic control in type 2 diabetes
Last updated June 12, 2026
Key finding
Blood glucose decreased by 0.71 mmol/L
This study investigated the potential of natural product-based treatments for type 2 diabetes and cardiovascular disease, finding significant reductions in various health markers.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Risk of bias
Some Concerns
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Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the potential of natural product-based treatments for type 2 diabetes and cardiovascular disease, finding significant reductions in various health markers.
Clinical relevance
These findings are significant as they suggest that natural supplements could be effective adjuncts to traditional diabetes treatments. By potentially lowering blood glucose and cholesterol levels, these interventions may help reduce the risk of complications associated with type 2 diabetes and cardiovascular disease, offering new avenues for patient care.
Keep in mind
Effectiveness of individual interventions remains unclear. Lack of detailed p-values for many outcomes. Potential variability in participant responses.
Published in
Journal Reference
Publication details and source links for this paper.
Dharmsheel S, Satyam KK, Shivangi S, Desh DS. Natural Products for Glycemic Control and Cardiovascular Health in Type 2 Diabetes: A Systematic Review. World Journal of Diabetes. 2024. doi:10.4239/wjd.v15.i7.1603
Main Effects
Blood glucose levels decreased by 0.71 mmol/L.
HbA1c levels decreased significantly.
Systolic blood pressure decreased significantly.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to American ginseng, Bilberry extract, Flavanol-rich cocoa, and 5 more and Blood glucose, HbA1c, Systolic blood pressure, and 6 more.
This study contributes evidence to
Primary intervention
American ginseng
Primary outcomes
- Blood glucose
- HbA1c
- Systolic blood pressure
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
14
Evidence pairs
14
Relationships
4
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 68
4
Related topics
14
Evidence pairs
979
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 14 evidence relationships
- Includes primary outcome data
- Linked to 4 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Add related evidence to your Evidence Tracker
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Primary evidence
Evidence relationship
Fish Oil Supplements and Adipokine and Angiogenic Markers
Related evidence
Evidence relationship
Fish Oil Supplements and Fasting Glucose
Save evidence
Evidence relationship
Fish Oil Supplements and Inflammatory Markers
Save evidence
Core evidence
Study findings
The primary outcomes reported in this study.
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerSystolic blood pressure
American ginseng → Systolic blood pressure
American ginseng → Systolic blood pressure
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Supporting studies: Based on 2 studies
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerC-reactive protein
Flaxseed oil and fish oil → C-reactive protein
Flaxseed oil and fish oil → C-reactive protein
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerFasting blood sugar (FBS)
Melissa officinalis capsules → Fasting blood sugar (FBS)
Melissa officinalis capsules → Fasting blood sugar (FBS)
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Supporting studies: Based on 2 studies
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerFasting blood sugar (FBS)
Nigella sativa oil → Fasting blood sugar (FBS)
Nigella sativa oil → Fasting blood sugar (FBS)
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEndothelial function
Terminalia chebula → Endothelial function
Terminalia chebula → Endothelial function
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerTotal cholesterol
Vitamin E supplementation → Total cholesterol
Vitamin E supplementation → Total cholesterol
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Evidence Suggest
- Blood glucose levels decreased by 0.71 mmol/L.
- HbA1c levels decreased significantly.
- Systolic blood pressure decreased significantly.
Keep in Mind
- Effectiveness of individual interventions remains unclear.
- Lack of detailed p-values for many outcomes.
- Potential variability in participant responses.
Between the Lines
- Effectiveness of individual interventions remains unclear.
- Lack of detailed p-values for many outcomes.
- Potential variability in participant responses.
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Bilberry extract and HbA1c, Melissa officinalis capsules and Fasting Glucose.
Related evidence relationships
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Bilberry extract → HbA1c
Supplements
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Supporting studies: Based on 2 studies
View evidenceSupplements
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 35
- mixed
Supporting studies: Based on 2 studies
View evidenceSupplements
American ginseng → Blood Pressure
Supplements
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceIncluded in these evidence collections
Curated evidence collections and hubs this study is part of.
Bilberry extract Evidence Hub
All studies on Bilberry extract
2 studies
intervention_hubContributes to Bilberry extract evidence base.
Fasting Glucose Evidence Hub
All studies measuring Fasting Glucose
2 studies
outcome_hubMeasures Fasting Glucose as a key outcome.
HbA1c Evidence Hub
All studies measuring HbA1c
2 studies
outcome_hubMeasures HbA1c as a key outcome.
Melissa officinalis capsules Evidence Hub
All studies on Melissa officinalis capsules
2 studies
intervention_hubContributes to Melissa officinalis capsules evidence base.
American ginseng Evidence Hub
All studies on American ginseng
1 studies
intervention_hubContributes to American ginseng evidence base.
Explore more in Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Bilberry extract and HbA1c
Intervention: Bilberry extractOutcome: HbA1c
2 results
All studies on Melissa officinalis capsules and Fasting blood sugar (FBS)
Intervention: Melissa officinalis capsulesOutcome: Fasting blood sugar (FBS)
2 results
All studies on Bilberry extract
Intervention: Bilberry extract
2 results
All studies on Melissa officinalis capsules
Intervention: Melissa officinalis capsules
2 results
All studies measuring HbA1c
Outcome: HbA1c
2 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Fish Oil Supplements improve fasting glucose?
Moderate Evidence
Fish Oil Supplements appears to improve Fasting Glucose.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Evidence caveat: The available evidence reports mixed findings.
Ranked evidence signals
- 1
Fasting blood sugar (FBS)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
- Only a small number of supporting studies are available.
- Population details are unavailable.
Does Fish Oil Supplements improve adipokine and angiogenic markers?
Moderate Evidence
Fish Oil Supplements may improve Adipokine and Angiogenic Markers.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Evidence caveat: The available evidence reports mixed findings.
Ranked evidence signals
- 1
Triglycerides
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
- Only a small number of supporting studies are available.
- Population details are unavailable.
Does Fish Oil Supplements improve inflammatory markers?
Emerging Evidence
Fish Oil Supplements appears to improve Inflammatory Markers.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
C-reactive protein
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Bilberry extract improve HbA1c?
Moderate Evidence
Bilberry extract may improve HbA1c.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Evidence caveat: The available evidence reports mixed findings.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
Next steps
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