StrongDecrease
Fasting Plasma Glucose (FPG)
Cinnamomum zeylanicum → Fasting Plasma Glucose (FPG)
Cinnamomum zeylanicum → Fasting Plasma Glucose (FPG)
Evidence profile
StrongDecreaseGlycemic Control
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Research Summary
Analyzed using Evidence Intelligence™
Cinnamomum zeylanicum improves glycemic control in type 2 diabetes
Key finding
Reduction in fasting blood glucose levels in the cinnamon group was found -35.50% (95% CI, -173 to 58.4).
This study evaluated the effects of Cinnamomum zeylanicum on glycemic control in individuals with type 2 diabetes, finding significant reductions in fasting plasma glucose levels.
Evidence strength
Moderate confidence
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Some Concerns bias
Last updated July 6, 2026Quick read
Study at a glance
The essential study design details in one scan.
Population
Young Adult (19–39), Middle Aged (40-64), Male, Female, Asia-Pacific (APAC), with T2 Diabetes
Intervention
Cinnamomum zeylanicum, Placebo
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Primary outcome
Fasting Plasma Glucose (FPG)
Comparator
Placebo Group
Plain-language summary
What this paper says
A plain-language read of the study's main message and where it applies.
Study focus
This study evaluated the effects of Cinnamomum zeylanicum on glycemic control in individuals with type 2 diabetes, finding significant reductions in fasting plasma glucose levels.
Clinical relevance
Effective management of blood sugar levels is crucial for individuals with type 2 diabetes to prevent complications. The significant reduction in fasting plasma glucose levels observed with Cinnamomum zeylanicum indicates its potential as a complementary treatment option, which could improve patient outcomes and enhance glycemic control strategies.
Keep in mind
The study's sample size may limit the generalizability of the findings. The duration of the intervention was not specified, which could affect long-term outcomes. Potential confounding factors were not fully addressed.
Published in
Journal Reference
Publication details and source links for this paper.
Alexander M, John RA, Anindita M, et al. Effects of Cinnamomum zeylanicum on Glycemic Control in Type 2 Diabetes: A Randomized Controlled Trial. Cureus. 2023;15(2):e35023. doi:10.7759/cureus.35023
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Main Effects
Cinnamomum zeylanicum reduced fasting plasma glucose by 35.5% (p=0.001).
Glycosylated hemoglobin (HbA1c) decreased by 0.85% in the cinnamon group (p=0.039).
Significant inhibition of PTP1B expression was observed (p=0.039).
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Cinnamomum zeylanicum and Fasting Plasma Glucose (FPG), HbA1c, PTP1B expression.
This study contributes evidence to
Primary intervention
Cinnamomum zeylanicum
Primary outcomes
- Fasting Plasma Glucose (FPG)
- HbA1c
- PTP1B expression
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
3
Evidence pairs
3
Relationships
2
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 64
2
Related topics
3
Evidence pairs
270
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 3 evidence relationships
- Includes primary outcome data
- Linked to 2 direct semantic evidence topics
Topic contributions
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Core evidence
Study findings
The primary outcomes reported in this study.
StrongDecrease
HbA1c
Cinnamomum zeylanicum → HbA1c
Cinnamomum zeylanicum → HbA1c
Evidence profile
StrongDecreaseGlycemic Control
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StrongDecrease
PTP1B expression
Cinnamomum zeylanicum → PTP1B expression
Cinnamomum zeylanicum → PTP1B expression
Evidence profile
StrongDecreaseMetabolic Health
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Evidence Suggest
- Cinnamomum zeylanicum led to a 35.5% decrease in fasting plasma glucose.
- A 0.85% reduction in HbA1c was noted with cinnamon treatment.
- PTP1B expression was significantly inhibited, indicating a possible mechanism.
Who this applies to
- Adults diagnosed with type 2 diabetes.
- Individuals seeking alternative treatments for glycemic control.
Keep in Mind
- Results may not apply to populations outside the study's demographic.
- Further research is needed to confirm long-term effects and safety.
- The study did not include a diverse range of participants, which may affect applicability.
Between the Lines
- The study's sample size may limit the generalizability of the findings.
- The duration of the intervention was not specified, which could affect long-term outcomes.
- Potential confounding factors were not fully addressed.
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Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Cinnamomum zeylanicum and Fasting Glucose, Cinnamomum zeylanicum and HbA1c.
Related evidence relationships
Explore in Evidence ArchiveThis study contributes to the evidence on the following intervention-outcome relationships.
Included in these evidence collections
Curated evidence collections and hubs this study is part of.
Cinnamomum zeylanicum Evidence Hub
All studies on Cinnamomum zeylanicum
1 studies
intervention_hubContributes to Cinnamomum zeylanicum evidence base.
Fasting Glucose Evidence Hub
All studies measuring Fasting Glucose
1 studies
outcome_hubMeasures Fasting Glucose as a key outcome.
HbA1c Evidence Hub
All studies measuring HbA1c
1 studies
outcome_hubMeasures HbA1c as a key outcome.
Explore more in the evidence archive
Jump to pre-filtered views in the evidence archive.
All studies on Cinnamomum zeylanicum and Fasting Plasma Glucose (FPG)
Intervention: Cinnamomum zeylanicumOutcome: Fasting Plasma Glucose (FPG)
1 results
All studies on Cinnamomum zeylanicum and HbA1c
Intervention: Cinnamomum zeylanicumOutcome: HbA1c
1 results
All studies on Cinnamomum zeylanicum
Intervention: Cinnamomum zeylanicum
1 results
All studies measuring Fasting Plasma Glucose (FPG)
Outcome: Fasting Plasma Glucose (FPG)
1 results
All studies measuring HbA1c
Outcome: HbA1c
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Cinnamomum zeylanicum improve fasting plasma glucose (fpg)?
Emerging Evidence
Cinnamomum zeylanicum appears to improve Fasting Plasma Glucose (FPG).
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Fasting Plasma Glucose (FPG)
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Cinnamomum zeylanicum improve HbA1c?
Emerging Evidence
Cinnamomum zeylanicum appears to improve HbA1c.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Cinnamomum zeylanicum improve ptp1b expression?
Emerging Evidence
Cinnamomum zeylanicum appears to improve PTP1B expression.
ConsensusScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
PTP1B expression
EvidenceScore™ Emerging | EvidenceScore™ 51.7 | strong positive | ConsensusScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Next steps
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