Last updated July 2, 2026
Key finding
The intervention groups significantly lowered the progression of type 2 diabetes among prediabetes individuals.
This study investigated the effects of dietary supplements on the risk of developing diabetes in individuals with prediabetes, finding that certain interventions reduced progression to overt diabetes.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
Save research, organize studies, and quickly find important evidence again.
Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study investigated the effects of dietary supplements on the risk of developing diabetes in individuals with prediabetes, finding that certain interventions reduced progression to overt diabetes.
These findings are significant as they suggest that dietary interventions can play a role in diabetes prevention. With the increasing prevalence of prediabetes, identifying effective strategies to halt its progression is crucial for public health. This study highlights the potential of specific dietary supplements in managing diabetes risk, which could inform clinical practices and dietary recommendations.
The study did not demonstrate significant effects on various metabolic parameters. The sample size and demographic characteristics may limit generalizability. The long-term effects of the interventions were not assessed.
Published in
Publication details and source links for this paper.
Preeyapat C, Tiersidh N, Korbtham S, Sathit N. The Effect of Dietary Supplements on Diabetic Risk in Prediabetes: A Randomized Controlled Trial. Journal of the Endocrine Society. 2022;6(Suppl 1):A269-A269. doi:10.1210/jendso/bvac150.554
The intervention groups significantly lowered the progression to overt diabetes among prediabetes individuals.
No significant effects were found on fasting plasma glucose levels.
No significant effects were observed on body weight changes.
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Curcumin plus fish oil, Curcumin plus fish oil and vitamin D and 2-hour plasma glucose, BMI, Body weight, and 4 more.
This study contributes evidence to
Primary intervention
Curcumin plus fish oil
Primary outcomes
Evidence topics
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
3
Related topics
14
Evidence pairs
998
Related studies
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Save studies and evidence pages, organize your personal Evidence Tracker, and keep the research you care about in one place.
Primary evidence
Evidence relationship
Related evidence
Evidence relationship
Save evidence
Evidence relationship
Save evidence
Core evidence
The primary outcomes reported in this study.
Curcumin plus fish oil → 2-hour plasma glucose
Curcumin plus fish oil → 2-hour plasma glucose
Curcumin plus fish oil → Fasting Plasma Glucose (FPG)
Curcumin plus fish oil → Fasting Plasma Glucose (FPG)
Curcumin plus fish oil → Progression to overt diabetes
Curcumin plus fish oil → Progression to overt diabetes
Curcumin plus fish oil and vitamin D → 2-hour plasma glucose
Curcumin plus fish oil and vitamin D → 2-hour plasma glucose
Curcumin plus fish oil and vitamin D → Body weight
Curcumin plus fish oil and vitamin D → Body weight
Curcumin plus fish oil and vitamin D → Fasting Plasma Glucose (FPG)
Curcumin plus fish oil and vitamin D → Fasting Plasma Glucose (FPG)
Curcumin plus fish oil and vitamin D → lipid profiles
Curcumin plus fish oil and vitamin D → lipid profiles
Curcumin plus fish oil and vitamin D → Progression to overt diabetes
Curcumin plus fish oil and vitamin D → Progression to overt diabetes
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Evidence Library
Save research, organize studies, and quickly find important evidence again.
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Curcumin Supplements and Postprandial and OGTT Glucose, Curcumin Supplements and Body Mass Index.
This study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Supplements
Curated evidence collections and hubs this study is part of.
All studies measuring Body Mass Index
Measures Body Mass Index as a key outcome.
All studies measuring Body Weight
Measures Body Weight as a key outcome.
All studies on Curcumin Supplements
Contributes to Curcumin Supplements evidence base.
All studies measuring Postprandial and OGTT Glucose
Measures Postprandial and OGTT Glucose as a key outcome.
Jump to pre-filtered views in Evidence Explorer.
1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Curcumin Supplements may improve HbA1c.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 3 supporting studies with generally consistent results and a positive effect signal.
Limitations
Curcumin Supplements may improve Fasting Glucose.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Fasting Plasma Glucose (FPG)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on 3 supporting studies with generally consistent results and a positive effect signal.
Limitations
Curcumin Supplements may improve Body Mass Index.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Ranked evidence signals
BMI
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
Current evidence does not show a clear benefit of Curcumin Supplements for Postprandial and OGTT Glucose.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
2-hour plasma glucose
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Next steps
Choose a next path through related evidence topics, Evidence Explorer views, and research summaries.
Follow the topics this study contributes to.
Open broader Evidence Explorer views for this relationship.
Read related research summaries.
Focused on evidence, not advertising.
Your data is always protected.
New studies added every day.
