Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerResearch Summary
Analyzed using Evidence Intelligence™
DREAM improves HbA1c in Cambodian-Americans with depression
Last updated August 29, 2026
Key finding
Depressive symptoms improved for EWS relative to SS.
The DREAM trial investigated diabetes prevention in Cambodian-Americans with depression, finding significant improvements in HbA1c and depressive symptoms with specific interventions.
Quick read
Study at a glance
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Long-Term (1–5 y)
Risk of bias
Some Concerns
Save research, organize studies, and quickly find important evidence again.
Plain-language summary
What this paper says
A plain-language read of the study’s main message and where it applies.
Study focus
The DREAM trial investigated diabetes prevention in Cambodian-Americans with depression, finding significant improvements in HbA1c and depressive symptoms with specific interventions.
Clinical relevance
This study highlights the importance of tailored interventions for at-risk populations, particularly those facing both diabetes and mental health challenges. By demonstrating that specific behavioral strategies can effectively lower HbA1c and improve depressive symptoms, it suggests potential pathways for enhancing diabetes prevention efforts in similar communities.
Keep in mind
Effectiveness of interventions remains unclear due to limited evidence. The study's population may not be generalizable to other ethnic groups. Potential confounding factors were not fully controlled.
Published in
Journal Reference
Publication details and source links for this paper.
Julie AW, Angela B, Thomas EB, et al. DREAM: A Diabetes Prevention Trial for Cambodian-Americans with Depression. Scientific Reports. 2023;13:8718. doi:10.1038/s41598-023-35738-9
Main Effects
EWS + MTM showed a significant decrease in HbA1c by -0.06% (p=0.011).
Depressive symptoms improved by -4.9 points for EWS and EWS + MTM compared to SS (p=0.043).
No change in insulin resistance was observed.
Evidence network
How this study fits
Understand where this research contributes within the broader evidence network.
Evidence Context
This study contributes evidence to Eat, Walk, Sleep (EWS) and Depression score, HbA1c, Insulin resistance.
This study contributes evidence to
Primary intervention
Eat, Walk, Sleep (EWS)
Primary outcomes
- Depression score
- HbA1c
- Insulin resistance
Evidence topics
Primary intervention
Primary outcomes
Evidence relationships
Intervention and outcome relationships this study adds to the evidence network.
3
Evidence pairs
3
Relationships
1
Evidence topics
contributes_evidence
Editorial context
Why this study matters
See why this paper is useful beyond its individual results.
Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
Moderate contributionModerate confidenceNetwork score: 59
1
Related topics
3
Evidence pairs
449
Related studies
High relevance in at least one topic
Why it is useful
- Contributes to 3 evidence relationships
- Includes primary outcome data
- Linked to 1 direct semantic evidence topic
Topic contributions
Evidence topic
Contributes evidence
Add related evidence to your Evidence Tracker
Save studies and evidence pages, organize your personal Evidence Tracker, and keep the research you care about in one place.
Primary evidence
Evidence topic
HbA1c Reduction
matched_outcome
Core evidence
Study findings
The primary outcomes reported in this study.
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 100
- consistent
Supporting studies: Based on 2 studies
Add to Evidence TrackerInsulin resistance
Eat, Walk, Sleep (EWS) → Insulin resistance
Eat, Walk, Sleep (EWS) → Insulin resistance
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 50
- Neutral
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
Add to Evidence TrackerEvidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Evidence Suggest
- EWS + MTM led to a significant HbA1c decrease of -0.06%.
- Depressive symptoms improved by -4.9 points with EWS and EWS + MTM.
- No changes in insulin resistance were found.
Who this applies to
- Cambodian-Americans with depression at risk for diabetes.
- Adults aged 18-65 with a diagnosis of depression.
Keep in Mind
- Results may not apply to populations outside of Cambodian-Americans.
- Further research is needed to confirm findings in broader contexts.
- The study did not address long-term effects of the interventions.
Between the Lines
- Effectiveness of interventions remains unclear due to limited evidence.
- The study's population may not be generalizable to other ethnic groups.
- Potential confounding factors were not fully controlled.
Evidence Library
Build your evidence library
Save research, organize studies, and quickly find important evidence again.
Connected Evidence
Explore related studies, evidence collections, and research questions.
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Eat, Walk, Sleep (EWS) and HbA1c, Eat, Walk, Sleep (EWS) and Mental Health.
Related evidence relationships
Explore in Evidence ExplorerThis study contributes to the evidence on the following intervention-outcome relationships.
Behavioral & Lifestyle
Eat, Walk, Sleep (EWS) → HbA1c
Behavioral & Lifestyle
Evidence Intelligence™
- EvidenceScore™
- Moderate
- Score 69 · Based on 2 studies
- ImpactScore™
- 75
- Positive
- ConsistencyScore™
- 100
- consistent
Supporting studies: Based on 2 studies
View evidenceBehavioral & Lifestyle
Eat, Walk, Sleep (EWS) → Mental Health
Behavioral & Lifestyle
Evidence Intelligence™
- EvidenceScore™
- Emerging
- Score 59 · Based on 1 study
- ImpactScore™
- 100
- Very Positive
- ConsistencyScore™
- unclear
- Not enough independent studies
Supporting studies: Based on 1 study
View evidenceIncluded in these evidence collections
Curated evidence collections and hubs this study is part of.
Eat, Walk, Sleep (EWS) Evidence Hub
All studies on Eat, Walk, Sleep (EWS)
2 studies
intervention_hubContributes to Eat, Walk, Sleep (EWS) evidence base.
HbA1c Evidence Hub
All studies measuring HbA1c
2 studies
outcome_hubMeasures HbA1c as a key outcome.
Mental Health Evidence Hub
All studies measuring Mental Health
1 studies
outcome_hubMeasures Mental Health as a key outcome.
Explore more in Evidence Explorer
Jump to pre-filtered views in Evidence Explorer.
All studies on Eat, Walk, Sleep (EWS) and HbA1c
Intervention: Eat, Walk, Sleep (EWS)Outcome: HbA1c
2 results
All studies on Eat, Walk, Sleep (EWS) and Depression score
Intervention: Eat, Walk, Sleep (EWS)Outcome: Depression score
1 results
All studies on Eat, Walk, Sleep (EWS)
Intervention: Eat, Walk, Sleep (EWS)
2 results
All studies measuring HbA1c
Outcome: HbA1c
2 results
All studies measuring Depression score
Outcome: Depression score
1 results
Questions answered by this study
Generated from the study's connected evidence using Evidence Intelligence™.
Does Eat, Walk, Sleep (EWS) improve HbA1c?
Moderate Evidence
Eat, Walk, Sleep (EWS) may improve HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
- 1
HbA1c
EvidenceScore™ Moderate | EvidenceScore™ 69.0 | moderate positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Population details are unavailable.
Does Eat, Walk, Sleep (EWS) improve depression score?
Emerging Evidence
Eat, Walk, Sleep (EWS) appears to improve Depression score.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Depression score
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Does Eat, Walk, Sleep (EWS) improve insulin resistance?
Emerging Evidence
Current evidence does not show a clear benefit of Eat, Walk, Sleep (EWS) for Insulin resistance.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
- 1
Insulin resistance
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
- Only one supporting study is available.
- Consistency cannot yet be determined.
- Population details are unavailable.
Next steps
Continue your research
Choose a next path through related evidence topics, Evidence Explorer views, and research summaries.
Explore in Evidence Explorer
Open broader Evidence Explorer views for this relationship.
Related research
Read related research summaries.
CHE interventions improve nutrition and activity in Cambodian refugeesAcupuncture with Diet May Improve Depression in DiabeticsAlmond-Based Diet Improves Depression and Glycometabolism in Type 2 DiabetesHIIT and Aerobic-Resistance Training Improve Diabetes OutcomesHRS-7535 improves glycemic control in adults with type 2 diabetes
No ads. No tracking.
Focused on evidence, not advertising.
Secure & private
Your data is always protected.
Always up to date
New studies added every day.