Last updated September 9, 2026
Key finding
Fasting blood glucose decreased from 6.44 ± 1.17 to 6.19 ± 1.14 mmol/L (p < 0.01).
This study evaluated the efficacy and safety of Korean red ginseng in a randomized controlled trial, finding significant improvements in glucose levels and immune function without adverse effects.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
This study evaluated the efficacy and safety of Korean red ginseng in a randomized controlled trial, finding significant improvements in glucose levels and immune function without adverse effects.
These findings are significant as they suggest that Korean red ginseng could be an effective and safe supplement for managing blood glucose levels and enhancing immune function in patients with type 2 diabetes. This could provide an additional therapeutic option for individuals seeking to improve their diabetes management.
The study's sample size and demographic characteristics may limit generalizability. Long-term effects of Korean red ginseng were not assessed. The study did not explore potential interactions with other diabetes medications.
Published in
Publication details and source links for this paper.
Guijun T, Li Z, Zihan Z, et al. Evaluation of the clinical efficacy and safety of Korean red ginseng through a randomized controlled trial. Journal of Ginseng Research. 2026;50(2):100917. doi:10.1016/j.jgr.2025.11.005
Fasting plasma glucose decreased from 6.44 ± 1.17 to 6.19 ± 1.14 mmol/L (p < 0.01).
2-hour blood glucose decreased from 11.96 ± 4.40 to 10.48 ± 3.72 mmol/L (p < 0.01).
HbA1c decreased from 6.27 ± 0.79 to 6.12 ± 0.81% (p < 0.01).
Red ginseng significantly increased IgA levels and natural killer cell activity in patients with type 2 diabetes.
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Korean Red Ginseng (KRG) and Fasting Plasma Glucose (FPG), Glucose iAUC (OGTT), HbA1c, and 2 more.
This study contributes evidence to
Primary intervention
Korean Red Ginseng (KRG)
Primary outcomes
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
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Evidence pairs
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Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Related evidence
Evidence topic
Save evidence
Core evidence
The primary outcomes reported in this study.
Korean Red Ginseng (KRG) → Fasting Plasma Glucose (FPG)
Korean Red Ginseng (KRG) → Fasting Plasma Glucose (FPG)
Korean Red Ginseng (KRG) → Glucose iAUC (OGTT)
Korean Red Ginseng (KRG) → Glucose iAUC (OGTT)
Korean Red Ginseng (KRG) → Natural Killer Cell Activity
Korean Red Ginseng (KRG) → Natural Killer Cell Activity
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Korean Red Ginseng (KRG) and Fasting Glucose, Korean Red Ginseng (KRG) and Postprandial and OGTT Glucose.
This study contributes to the evidence on the following intervention-outcome relationships.
Supplements
Curated evidence collections and hubs this study is part of.
All studies measuring Fasting Glucose
Measures Fasting Glucose as a key outcome.
All studies on Korean Red Ginseng (KRG)
Contributes to Korean Red Ginseng (KRG) evidence base.
All studies measuring Postprandial and OGTT Glucose
Measures Postprandial and OGTT Glucose as a key outcome.
Latest published studies
Published within the last 2 years.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Korean Red Ginseng (KRG) appears to improve fasting plasma glucose (FPG).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Fasting Plasma Glucose (FPG)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Korean Red Ginseng (KRG) appears to improve glucose iauc (OGTT).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Glucose iAUC (OGTT)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Korean Red Ginseng (KRG) appears to lower HbA1c.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
HbA1c
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Korean Red Ginseng (KRG) appears to improve iga.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
IgA
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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