Last updated August 21, 2026
Key finding
Postprandial glucose after the low-GI test meal was significantly lower than after the high-GI test meal (35%, p < 0.001).
The study evaluated the impact of a Low-GI Mediterranean diet on glycemic control in adults at risk for Type 2 diabetes, finding significant improvements in postprandial glucose levels.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
The study evaluated the impact of a Low-GI Mediterranean diet on glycemic control in adults at risk for Type 2 diabetes, finding significant improvements in postprandial glucose levels.
Improving glycemic control is crucial for preventing Type 2 diabetes and its complications. This study suggests that adopting a Low-GI Mediterranean diet can be an effective dietary strategy for individuals at risk, potentially reducing their chances of developing diabetes and improving overall health outcomes.
Limited generalizability due to specific population characteristics. Potential confounding factors not controlled for in the study. Short duration of the intervention may not reflect long-term effects.
Published in
Publication details and source links for this paper.
Robert EB, Rosalba G, Therese H, et al. The Mediterranean Diet with Low-Glycemic Index Foods Improves Glycemic Control in Adults at Risk for Type 2 Diabetes. Nutrients. 2022;14(3):706. doi:10.3390/nu14030706
Postprandial plasma glucose response decreased by 35% after the Low-GI meal compared to the High-GI meal (p < 0.001).
Postprandial insulin concentrations were higher after the High-GI meal at baseline but not post-intervention (p = 0.17).
Indices of 24-h glycemic variability were significantly reduced in the Low-GI group compared to baseline.
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to High-GI Mediterranean-style healthy eating pattern, Low-GI Mediterranean-style healthy eating pattern and Glucose iAUC (OGTT), Indices of 24-hour glycemic variability, Postprandial insulin AUC.
This study contributes evidence to
Primary intervention
High-GI Mediterranean-style healthy eating pattern
Primary outcomes
Evidence topics
Primary intervention
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
1
Related topics
6
Evidence pairs
368
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Evidence topic
Contributes evidence
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Primary evidence
Evidence topic
matched_outcome
Core evidence
The primary outcomes reported in this study.
High-GI Mediterranean-style healthy eating pattern → Glucose iAUC (OGTT)
High-GI Mediterranean-style healthy eating pattern → Glucose iAUC (OGTT)
High-GI Mediterranean-style healthy eating pattern → Indices of 24-hour glycemic variability
High-GI Mediterranean-style healthy eating pattern → Indices of 24-hour glycemic variability
High-GI Mediterranean-style healthy eating pattern → Postprandial insulin AUC
High-GI Mediterranean-style healthy eating pattern → Postprandial insulin AUC
Low-GI Mediterranean-style healthy eating pattern → Glucose iAUC (OGTT)
Low-GI Mediterranean-style healthy eating pattern → Glucose iAUC (OGTT)
Low-GI Mediterranean-style healthy eating pattern → Indices of 24-hour glycemic variability
Low-GI Mediterranean-style healthy eating pattern → Indices of 24-hour glycemic variability
Low-GI Mediterranean-style healthy eating pattern → Postprandial insulin AUC
Low-GI Mediterranean-style healthy eating pattern → Postprandial insulin AUC
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on High-GI Mediterranean-style healthy eating pattern and Postprandial and OGTT Glucose, High-GI Mediterranean-style healthy eating pattern and Indices of 24-hour glycemic variability.
This study contributes to the evidence on the following intervention-outcome relationships.
Diet and Nutrition
Diet and Nutrition
Curated evidence collections and hubs this study is part of.
All studies on High-GI Mediterranean-style healthy eating pattern
Contributes to High-GI Mediterranean-style healthy eating pattern evidence base.
All studies measuring Indices of 24-hour glycemic variability
Measures Indices of 24-hour glycemic variability as a key outcome.
All studies measuring Postprandial and OGTT Glucose
Measures Postprandial and OGTT Glucose as a key outcome.
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1 results
1 results
1 results
1 results
1 results
Generated from the study's connected evidence using Evidence Intelligence™.
Low-GI Mediterranean-style healthy eating pattern appears to improve Glucose iAUC (OGTT).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Glucose iAUC (OGTT)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Low-GI Mediterranean-style healthy eating pattern appears to improve Indices of 24-hour glycemic variability.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Indices of 24-hour glycemic variability
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of High-GI Mediterranean-style healthy eating pattern for Glucose iAUC (OGTT).
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Glucose iAUC (OGTT)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
Current evidence does not show a clear benefit of High-GI Mediterranean-style healthy eating pattern for Indices of 24-hour glycemic variability.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Indices of 24-hour glycemic variability
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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