Glycemic Control has evidence across 10 diabetes-related interventions, with strongest support for Diabetes Self-Management Education and Support (DSMES) Programs, Diabetes Self-Management Education and Support (DSMES) Programs and Insulin Delivery Systems.
Evidence Intelligence™
Every evidence topic is generated from structured relationships across diabetes research, including topics, interventions, outcomes, and individual studies.
| Rank | Intervention group | Outcome group | EvidenceScore™ | ImpactScore™ | Consistency | Studies | Effectiveness | Action |
|---|---|---|---|---|---|---|---|---|
| #1 | Diabetes Self-Management Education and Support (DSMES) Programs | Fasting Glucose | 89/100Strong | 67/100Slightly Positive | 35/100mixed | 22 | weak_positive | Explore evidence |
| #2 | Diabetes Self-Management Education and Support (DSMES) Programs | HbA1c | 88/100Strong | 79/100Positive | 69/100generally_consistent | 44 | moderate_positive | Explore evidence |
| #3 | Insulin Delivery Systems | HbA1c | 88/100Strong | 86/100Very Positive | 85/100consistent | 21 | strong_positive | Explore evidence |
| #4 | Insulin Delivery Systems | CGM Time in Range | 88/100Strong | 72/100Positive | 57/100generally_consistent | 38 | moderate_positive | Explore evidence |
| #5 | Insulin Therapies | HbA1c | 88/100Strong | 72/100Positive | 63/100generally_consistent | 19 | moderate_positive | Explore evidence |
| #6 | GLP-1 Receptor Agonists | HbA1c | 87/100Strong | 90/100Very Positive | 95/100consistent | 45 | strong_positive | Explore evidence |
| #7 | SGLT2 Inhibitors | HbA1c | 86/100Strong | 84/100Positive | 92/100consistent | 27 | moderate_positive | Explore evidence |
| #8 | Sulfonylureas | HbA1c | 86/100Strong | 78/100Positive | 67/100generally_consistent | 9 | moderate_positive | Explore evidence |
| #9 | Thiazolidinediones | HbA1c | 86/100Strong | 94/100Very Positive | 100/100consistent | 8 | strong_positive | Explore evidence |
| #10 | DPP-4 Inhibitors | HbA1c | 86/100Strong | 96/100Very Positive | 100/100consistent | 12 | strong_positive | Explore evidence |
Diabetes Self-Management Education and Support (DSMES) Programs → Fasting Glucose
Diabetes Self-Management Education and Support (DSMES) Programs → HbA1c
Insulin Delivery Systems → HbA1c
Insulin Delivery Systems → CGM Time in Range
Insulin Therapies → HbA1c
GLP-1 Receptor Agonists → HbA1c
SGLT2 Inhibitors → HbA1c
Sulfonylureas → HbA1c
Thiazolidinediones → HbA1c
DPP-4 Inhibitors → HbA1c
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
Hybrid closed-loop system, Lifestyle intervention for prediabetes, and Low-carbohydrate diet have the strongest available evidence signals for Glycemic Control.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Hybrid closed-loop system
EvidenceScore™ Strong | EvidenceScore™ 87.7 | moderate positive | ConsistencyScore™ Generally Consistent | 21 studies
Lifestyle intervention for prediabetes
EvidenceScore™ Strong | EvidenceScore™ 87.4 | strong positive | ConsistencyScore™ Consistent | 17 studies
Low-carbohydrate diet
EvidenceScore™ Strong | EvidenceScore™ 86.0 | moderate positive | ConsistencyScore™ Generally Consistent | 24 studies
Why this answer: This answer is based on 62 supporting studies with generally consistent results and a positive effect signal.
Continuous glucose monitoring, Hybrid closed-loop system, and Low-carbohydrate diet are among the most studied areas in relation to Glycemic Control.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Hybrid closed-loop system
EvidenceScore™ Strong | EvidenceScore™ 87.7 | moderate positive | ConsistencyScore™ Generally Consistent | 25 studies
Continuous glucose monitoring
EvidenceScore™ Strong | EvidenceScore™ 87.6 | moderate positive | ConsistencyScore™ Generally Consistent | 26 studies
Low-carbohydrate diet
EvidenceScore™ Strong | EvidenceScore™ 86.0 | moderate positive | ConsistencyScore™ Generally Consistent | 31 studies
Why this answer: This answer is cautious because the available studies report mixed findings.
Results are mixed or unclear for whey protein 20g, Acarbose, and Basal insulin in relation to Glycemic Control.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Ranked evidence signals
Lifestyle intervention for prediabetes
EvidenceScore™ Strong | EvidenceScore™ 87.1 | moderate positive | ConsistencyScore™ Mixed | 9 studies
Non-surgical periodontal treatment
EvidenceScore™ Strong | EvidenceScore™ 84.0 | moderate positive | ConsistencyScore™ Mixed | 14 studies
Continuous glucose monitoring
EvidenceScore™ Strong | EvidenceScore™ 82.7 | weak positive | ConsistencyScore™ Mixed | 9 studies
Why this answer: This answer is cautious because the available studies report mixed findings.
1 g omega-3 fatty acids daily and Low-carbohydrate diet need more research in relation to Glycemic Control.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
1 g omega-3 fatty acids daily
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
Low-carbohydrate diet
EvidenceScore™ Emerging | EvidenceScore™ 56.1 | strong positive | ConsistencyScore™ Consistent | 2 studies
Why this answer: This answer is based on 3 supporting studies and existing graph evidence signals.
Hybrid closed-loop system and Semaglutide have available evidence for Glycemic Control, but the comparison requires review of the underlying studies.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Semaglutide
EvidenceScore™ Strong | EvidenceScore™ 88.2 | strong positive | ConsistencyScore™ Consistent | 16 studies
Hybrid closed-loop system
EvidenceScore™ Strong | EvidenceScore™ 87.7 | moderate positive | ConsistencyScore™ Generally Consistent | 21 studies
Why this answer: This answer is based on 37 supporting studies with generally consistent results and a positive effect signal.
Intervention categories most commonly studied for glycemic control outcomes.
Evidence related to SGLT2 inhibitor therapies in diabetes studies.
Evidence related to insulin therapies in diabetes studies.
Evidence related to Sulfonylureas.
Evidence related to diabetes self-management education and support programs in diabetes studies.
Evidence related to DPP-4 inhibitor therapies in diabetes studies.
Evidence related to metformin therapies in diabetes studies.
Each bubble represents an evidence relationship. Position shows effectiveness and EvidenceScoreâ„¢; size reflects study volume.
Evidence Workspace
Save evidence topics and organize the research that matters to you.
