Glycemic Control has evidence across 10 diabetes-related interventions, with strongest support for Diabetes Self-Management Education and Support (DSMES) Programs, Insulin Delivery Systems and Insulin Delivery Systems.
Evidence Intelligence™
Every evidence topic is generated from structured relationships across diabetes research, including topics, interventions, outcomes, and individual studies.
| Rank | Intervention group | Outcome group | EvidenceScore™ | ImpactScore™ | Consistency | Studies | Effectiveness | Action |
|---|---|---|---|---|---|---|---|---|
| #1 | Diabetes Self-Management Education and Support (DSMES) Programs | Fasting Glucose | 89/100Strong | 70/100Positive | 35/100mixed | 20 | moderate_positive | Explore evidence |
| #2 | Insulin Delivery Systems | HbA1c | 88/100Strong | 88/100Very Positive | 88/100consistent | 17 | strong_positive | Explore evidence |
| #3 | Insulin Delivery Systems | CGM Time in Range | 88/100Strong | 69/100Positive | 35/100mixed | 27 | moderate_positive | Explore evidence |
| #4 | Diabetes Self-Management Education and Support (DSMES) Programs | HbA1c | 88/100Strong | 79/100Positive | 69/100generally_consistent | 41 | moderate_positive | Explore evidence |
| #5 | Insulin Therapies | HbA1c | 88/100Strong | 75/100Positive | 73/100generally_consistent | 15 | moderate_positive | Explore evidence |
| #6 | SGLT2 Inhibitors | HbA1c | 86/100Strong | 82/100Positive | 89/100consistent | 22 | moderate_positive | Explore evidence |
| #7 | GLP-1 Receptor Agonists | HbA1c | 86/100Strong | 90/100Very Positive | 94/100consistent | 33 | strong_positive | Explore evidence |
| #8 | DPP-4 Inhibitors | HbA1c | 86/100Strong | 96/100Very Positive | 100/100consistent | 11 | strong_positive | Explore evidence |
| #9 | Metformin Therapies | Fasting Glucose | 85/100Strong | 73/100Positive | 35/100mixed | 11 | moderate_positive | Explore evidence |
| #10 | Probiotics and Synbiotics | HbA1c | 85/100Strong | 95/100Very Positive | 100/100consistent | 11 | strong_positive | Explore evidence |
Diabetes Self-Management Education and Support (DSMES) Programs → Fasting Glucose
Insulin Delivery Systems → HbA1c
Insulin Delivery Systems → CGM Time in Range
Diabetes Self-Management Education and Support (DSMES) Programs → HbA1c
Insulin Therapies → HbA1c
SGLT2 Inhibitors → HbA1c
GLP-1 Receptor Agonists → HbA1c
DPP-4 Inhibitors → HbA1c
Metformin Therapies → Fasting Glucose
Probiotics and Synbiotics → HbA1c
Relationships organized using the Dediabetes Evidence Intelligence™ framework.
Hybrid closed-loop system, Low-carbohydrate diet, and Non-surgical periodontal treatment have the strongest available evidence signals for Glycemic Control.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Hybrid closed-loop system
EvidenceScore™ Strong | EvidenceScore™ 87.9 | moderate positive | ConsistencyScore™ Generally Consistent | 17 studies
Low-carbohydrate diet
EvidenceScore™ Strong | EvidenceScore™ 85.4 | strong positive | ConsistencyScore™ Generally Consistent | 16 studies
Non-surgical periodontal treatment
EvidenceScore™ Strong | EvidenceScore™ 84.0 | moderate positive | ConsistencyScore™ Mixed | 14 studies
Why this answer: This answer is based on 47 supporting studies with generally consistent results and a positive effect signal.
Limitations
Hybrid closed-loop system, Insulin therapy, and Low-carbohydrate diet are among the most studied areas in relation to Glycemic Control.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
Hybrid closed-loop system
EvidenceScore™ Strong | EvidenceScore™ 87.9 | moderate positive | ConsistencyScore™ Generally Consistent | 20 studies
Low-carbohydrate diet
EvidenceScore™ Strong | EvidenceScore™ 85.4 | strong positive | ConsistencyScore™ Generally Consistent | 21 studies
Insulin therapy
EvidenceScore™ Strong | EvidenceScore™ 83.3 | moderate positive | ConsistencyScore™ Generally Consistent | 15 studies
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
Results are mixed or unclear for Acarbose, Bilberry extract, and Continuous glucose monitoring in relation to Glycemic Control.
ConsistencyScore™: Results are mixed and should be interpreted cautiously.
Ranked evidence signals
Non-surgical periodontal treatment
EvidenceScore™ Strong | EvidenceScore™ 84.0 | moderate positive | ConsistencyScore™ Mixed | 14 studies
Insulin therapy
EvidenceScore™ Strong | EvidenceScore™ 79.0 | moderate positive | ConsistencyScore™ Mixed | 10 studies
Mediterranean diet
EvidenceScore™ Strong | EvidenceScore™ 79.0 | moderate positive | ConsistencyScore™ Mixed | 4 studies
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
10 kHz Spinal Cord Stimulation (SCS), 5:2 diet, and Low-carbohydrate diet need more research in relation to Glycemic Control.
ConsistencyScore™: Consistency cannot yet be determined from the available evidence.
Ranked evidence signals
10 kHz Spinal Cord Stimulation (SCS)
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | strong positive | ConsistencyScore™ Unclear | 1 study
5:2 diet
EvidenceScore™ Emerging | EvidenceScore™ 59.0 | neutral | ConsistencyScore™ Unclear | 1 study
Low-carbohydrate diet
EvidenceScore™ Emerging | EvidenceScore™ 56.1 | strong positive | ConsistencyScore™ Consistent | 2 studies
Why this answer: This answer is based on 4 supporting studies and existing graph evidence signals.
Limitations
DSMES and Hybrid closed-loop system have available evidence for Glycemic Control, but the comparison requires review of the underlying studies.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Hybrid closed-loop system
EvidenceScore™ Strong | EvidenceScore™ 87.9 | moderate positive | ConsistencyScore™ Generally Consistent | 17 studies
DSMES
EvidenceScore™ Strong | EvidenceScore™ 86.1 | moderate positive | ConsistencyScore™ Generally Consistent | 11 studies
Why this answer: This answer is cautious because the available studies report mixed findings.
Limitations
Intervention categories most commonly studied for glycemic control outcomes.
Evidence related to insulin therapies in diabetes studies.
Evidence related to SGLT2 inhibitor therapies in diabetes studies.
Evidence related to diabetes self-management education and support programs in diabetes studies.
Evidence related to metformin therapies in diabetes studies.
Evidence related to DPP-4 inhibitor therapies in diabetes studies.
Evidence related to bariatric procedures in diabetes studies.
Each bubble represents an evidence relationship. Position shows effectiveness and EvidenceScoreâ„¢; size reflects study volume.
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