July 2026
Published Jul 17, 2026RCTs
This study examined the effects of Early Time-Restricted Eating combined with Daily Caloric Restriction on glucose levels in adults with overweight or obesity, finding a lower day-night sensor ratio in the E-TRE+DCR group.
Interventions
Time-Restricted Eating (TRE)
Outcomes
Coefficient of variationCount of glucose excursions above 120 mg/dLDifference in day-night sensor ratio between E-TRE+DCR and DCR groups at week 12+7 more
Added to Dediabetes Jul 17, 2026
Published Jul 17, 2026RCTs
This study investigated the effects of intermittent fasting strategies on weight loss and insulin resistance in night shift workers, finding no significant differences in body weight or insulin resistance compared to continuous energy restriction.
Interventions
Calorie restrictionIntermittent Fasting (IF)
Outcomes
Body weightInsulin resistanceLDL cholesterol+1 more
Added to Dediabetes Jul 17, 2026
Published Jul 17, 2026RCTs
This study investigated the effects of a short-term ketogenic diet on the gut microbiome in severely obese, prediabetic patients, revealing significant changes in microbiota composition.
Interventions
Low-carbohydrate dietStandard diet
Outcomes
Bacteroidaceae levels in standard diet groupGut microbiota diversityIncrease in Bacteroidaceae after ketogenic diet+1 more
Added to Dediabetes Jul 17, 2026
Published Jul 17, 2026RCTs
Structured lifestyle modification counseling significantly improved weight and BMI in adults with type 2 diabetes compared to routine clinical care.
Interventions
Behavioral counselingUsual care
Outcomes
Body Mass Index (BMI) changeBody weightWeight change
Added to Dediabetes Jul 17, 2026
Published Jul 17, 2026RCTs
This study evaluated the effects of Vildagliptin on insulin resistance and weight reduction in newly diagnosed Type 2 Diabetes patients, showing significant improvements in several metabolic parameters.
Interventions
Dipeptidyl peptidase-4 inhibitorsGliclazide sustained release
Outcomes
Advanced glycation end products (AGEs)Body weightHbA1c+1 more
Added to Dediabetes Jul 17, 2026
Published Jul 17, 2026RCTs
This study evaluated the effects of adding empagliflozin, pioglitazone, or glimepiride to metformin and DPP-4 inhibitors in patients with type 2 diabetes, showing improvements in glycemic control.
Interventions
EmpagliflozinGlimepiridePioglitazone
Outcomes
Frequency of hypoglycemic episodes at 180 minutesHbA1cWeight change
Added to Dediabetes Jul 17, 2026
Published Jul 17, 2026RCTs
This study investigated the effects of intermittent fasting on glycemic control in adults with type 2 diabetes, finding significant improvements in several metabolic markers.
Interventions
Intermittent Fasting (IF)
Outcomes
BMIFasting Plasma Glucose (FPG)HbA1c+2 more
Added to Dediabetes Jul 17, 2026
Published Jul 17, 2026RCTs
This study evaluated the efficacy of once-daily oral semaglutide 25 mg in adults with obesity and type 2 diabetes, finding significant weight reduction compared to placebo.
Outcomes
Gastrointestinal disorders incidenceProportion of participants achieving weight loss of 15% or more at 52 weeksProportion of participants achieving weight loss of 5% or more at 52 weeks+2 more
Added to Dediabetes Jul 17, 2026
Published Jul 17, 2026RCTs
This study evaluated the effectiveness of a very low-calorie diet (VLCD) in newly diagnosed type 2 diabetes patients, finding significant improvements in insulin resistance and other metabolic markers.
Interventions
Very-low-calorie ketogenic diet
Outcomes
Body weightFasting Plasma Glucose (FPG)Fasting insulin levels+3 more
Added to Dediabetes Jul 17, 2026
Published Jul 17, 2026RCTs
This study evaluated the effects of time-restricted feeding on glycaemic regulation and weight changes in overweight patients with type 2 diabetes, finding significant improvements in various health markers.
Interventions
Time-Restricted Eating (TRE)
Outcomes
Body weightChange in social functioning domain of health-related quality of lifeFasting Plasma Glucose (FPG)+8 more
Added to Dediabetes Jul 17, 2026
