Research feed

Latest Diabetes Research

Recently added diabetes research, organized by intervention and outcome.

Sorted by when Dediabetes added each study.

Last updated: Sep 12, 20261,338 studies indexed

July 2026

Added to Dediabetes Jul 21, 2026RCTs

Dietary fiber improves liver fibrosis and glycemic control in diabetes

This study evaluated the effects of dietary fiber supplementation on liver fibrosis and glycemic control in patients with Type 2 diabetes and MASLD, finding significant improvements in HbA1c and FIB-4 levels.

Interventions
DSMESDietary fibre supplement (YMETA)
Outcomes
BMIFIB-4 indexFasting Plasma Glucose (FPG)+1 more
Added to Dediabetes Jul 21, 2026RCTs

5:2 Diet Improves Glycemic Control in Type 2 Diabetes

The IDEATE study examined the effects of a 5:2 diet and exercise on glycemic control in newly diagnosed type 2 diabetes patients, finding significant improvements in HbA1c levels with the diet.

Interventions
5:2 dietExercise therapy
Outcomes
Adiposity indicesBody weightHbA1c+2 more
Added to Dediabetes Jul 21, 2026RCTs

Testosterone therapy reduces liver fat in men with diabetes

This study investigated the effects of testosterone therapy on liver fat in men with type 2 diabetes and low testosterone levels, finding a significant reduction in liver fat compared to placebo.

Interventions
Testosterone therapy
Outcomes
Alanine Aminotransferase (ALT)Liver fat content
Added to Dediabetes Jul 21, 2026RCTs

Oral insulin may improve liver health in diabetes patients

This study evaluated the safety and potential therapeutic effects of orally delivered insulin in patients with metabolic dysfunction-associated steatohepatitis and type 2 diabetes mellitus, finding significant reductions in liver fat and fibrosis levels.

Interventions
Insulin therapy
Outcomes
Cardiovascular eventsLiver fat contentMean change in Hemoglobin A1c levels after 12 weeks+3 more
Added to Dediabetes Jul 21, 2026RCTs

Pioglitazone may reduce liver fat more in women than men

This study investigated the efficacy of pioglitazone in treating NAFLD patients with abnormal glucose metabolism, revealing significant liver fat content reduction in women compared to men.

Interventions
Pioglitazone
Outcomes
Liver fat content
Added to Dediabetes Jul 21, 2026RCTs

Combination therapy improves hepatic steatosis in T2DM patients

This study evaluated the combination therapy of Tofogliflozin and Pioglitazone for treating hepatic steatosis in patients with NAFLD and T2DM, showing significant improvements in various metabolic parameters.

Interventions
Dapagliflozin plus linagliptin combination therapyPioglitazoneTofogliflozin
Outcomes
AdiponectinAlanine Aminotransferase (ALT)Change in ketone body levels after combination therapy+4 more
Added to Dediabetes Jul 21, 2026RCTs

Vildagliptin and Metformin Improve Glycemic Control in Type 2 Diabetes

This study investigated the effects of Vildagliptin and Metformin on hepatic steatosis in newly diagnosed Type 2 diabetes patients, showing significant improvements in various metabolic parameters.

Interventions
Dipeptidyl peptidase-4 inhibitorsMetformin
Outcomes
BMIBody weightChange in Hepatic Steatosis Index (HSI)+5 more
Added to Dediabetes Jul 21, 2026RCTs

MK-3655 shows modest reduction in liver fat for pre-cirrhotic MASH

The Phase 2b trial evaluated the safety and efficacy of MK-3655 in patients with pre-cirrhotic MASH. Results showed varying rates of MASH resolution and liver fat content reduction across different doses.

Interventions
HD-6277 50 mgMK-3655 300 mgResmetirom (100 mg)
Outcomes
Liver fat contentResolution of Metabolic Dysfunction Associated Steatohepatitis (MASH)
Added to Dediabetes Jul 21, 2026RCTs

Pioglitazone and Metformin Reduce Liver Fat in Diabetes

The study investigated the effects of combined treatment with pioglitazone and metformin on liver fat in type 2 diabetes patients, finding a significant reduction in liver fat content.

Interventions
MetforminPioglitazone
Outcomes
Blood lipidBody weightLiver fat content+3 more
Added to Dediabetes Jul 21, 2026RCTs

Semaglutide improves liver health and lipid levels in diabetes

This study evaluated the effects of semaglutide on lipid profiles and liver parameters in patients with type 2 diabetes and obesity, showing significant improvements.

Interventions
PioglitazoneSemaglutideSubcutaneous Semaglutide
Outcomes
ASTAlanine Aminotransferase (ALT)BMI+8 more

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