Última actualización 12 de julio de 2026
Key finding
HbA1c decreased from 10.2% to 9.1% after 6 months of AHCL therapy.
The study investigated the experiences of youth with Type 1 diabetes starting advanced hybrid closed-loop therapy, revealing significant improvements in HbA1c and overall satisfaction.
Quick read
The essential study design details in one scan.
EvidenceScore™
Moderate
Study type
RCTs
Follow-up
Medium-Term (3–12 mo)
Risk of bias
Some Concerns
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Plain-language summary
A plain-language read of the study’s main message and where it applies.
Study focus
The study investigated the experiences of youth with Type 1 diabetes starting advanced hybrid closed-loop therapy, revealing significant improvements in HbA1c and overall satisfaction.
These findings highlight the potential of advanced hybrid closed-loop therapy to enhance diabetes management in youth, leading to better health outcomes and improved quality of life. As diabetes distress can significantly impact mental health, addressing these factors is crucial for holistic care.
Effectiveness of the therapy remains unclear due to lack of statistical significance. Limited sample size may affect the generalizability of the findings. The study did not include long-term follow-up data.
Published in
Publication details and source links for this paper.
Alison R, Julie D, Selena L, et al. Experiences of Youth with Type 1 Diabetes Commencing Advanced Hybrid Closed-Loop Therapy. Pediatric Diabetes. 2024;2024:6260002. doi:10.1155/2024/6260002
HbA1c decreased from 10.2% to 9.1%, indicating improved glycemic control.
Diabetes distress score increased from 35.3 to 41.5, suggesting heightened emotional challenges.
Participants reported improved quality of sleep and energy levels.
Evidence network
Understand where this research contributes within the broader evidence network.
This study contributes evidence to Hybrid closed-loop system and Diabetes distress scores, Energy Levels, HbA1c, and 3 more.
This study contributes evidence to
Primary intervention
Hybrid closed-loop system
Primary outcomes
Evidence topics
Primary intervention
Primary outcomes
Intervention and outcome relationships this study adds to the evidence network.
Editorial context
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Evidence network role
This section describes how the study fits into the current evidence network. It does not determine whether an intervention works on its own.
3
Related topics
6
Evidence pairs
503
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Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
Evidence topic
Contributes evidence
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Evidencia principal
Relación de evidencia
Evidencia relacionada
Relación de evidencia
Guardar evidencia
Relación de evidencia
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Core evidence
The primary outcomes reported in this study.
Hybrid closed-loop system → Diabetes distress scores
Hybrid closed-loop system → Diabetes distress scores
Hybrid closed-loop system → Satisfaction with diabetes management
Hybrid closed-loop system → Satisfaction with diabetes management
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Relationships organized using the Dediabetes Evidence Intelligence™ framework.
This study contributes to evidence on Insulin Delivery Systems and CGM Time in Range, Insulin Delivery Systems and HbA1c.
This study contributes to the evidence on the following intervention-outcome relationships.
Devices & Technology
Devices & Technology
Devices & Technology
Curated evidence collections and hubs this study is part of.
All studies measuring CGM Time in Range
Measures CGM Time in Range as a key outcome.
All studies on Insulin Delivery Systems
Contributes to Insulin Delivery Systems evidence base.
All studies measuring HbA1c
Measures HbA1c as a key outcome.
All studies measuring Quality of Life Outcomes
Measures Quality of Life Outcomes as a key outcome.
Latest published studies
Published within the last 2 years.
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8 results
5 results
8 results
8 results
5 results
Generated from the study's connected evidence using Evidence Intelligence™.
Insulin Delivery Systems may improve CGM Time in Range.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Time in range
EvidenceScore™ Strong | EvidenceScore™ 81.0 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 17 supporting studies with generally consistent results and a positive effect signal.
Limitations
Insulin Delivery Systems may improve Quality of Life Outcomes.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Sleep quality
EvidenceScore™ Strong | EvidenceScore™ 79.0 | weak positive | ConsistencyScore™ Mixed | 1 study
Why this answer: This answer is based on 5 supporting studies with generally consistent results and a positive effect signal.
Limitations
Insulin Delivery Systems appears to improve HbA1c.
ConsistencyScore™: Results are consistent across studies.
Ranked evidence signals
HbA1c
EvidenceScore™ Strong | EvidenceScore™ 80.2 | strong positive | ConsistencyScore™ Consistent | 1 study
Why this answer: This answer is based on 13 supporting studies with consistent results and a positive effect signal.
Limitations
Hybrid closed-loop system may improve Diabetes distress scores.
ConsistencyScore™: Results are generally consistent across studies.
Ranked evidence signals
Diabetes distress scores
EvidenceScore™ Strong | EvidenceScore™ 79.0 | moderate positive | ConsistencyScore™ Generally Consistent | 1 study
Why this answer: This answer is based on a single supporting study.
Limitations
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